Mapping the tRNA binding site on the surface of human DNMT2 methyltransferase

Biochemistry

Volumn 51, Issue 22, 2012, Pages 4438-4444

  Jurkowski, Tomasz P ^a,b   Shanmugam, Raghuvaran ^a,b   Helm, Mark ^c   Jeltsch, Albert ^a,b  

^a JACOBS UNIVERSITY BREMEN   (Germany)

^b UNIVERSITY OF STUTTGART   (Germany)

^c JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICODON LOOP; ANTICODONS; ARGININE RESIDUE; BINDING POCKETS; CATALYTIC RESIDUE; COCRYSTAL STRUCTURE; COFACTORS; CONFORMATIONAL CHANGE; METHYL GROUP; METHYLTRANSFERASES; S ADENOSYL L METHIONINES; TRANSITION STATE; TRNA BINDING; WILD TYPES;

ALKYLATION; ARGININE; CATALYST ACTIVITY; ENZYMES; FUNCTIONAL GROUPS;

BINDING SITES;

ARGININE; DNA METHYLTRANSFERASE 2; LYSINE; METHYLTRANSFERASE; S ADENOSYLMETHIONINE; TRANSFER RNA; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CATALYSIS; CONTROLLED STUDY; HUMAN; PRIORITY JOURNAL; RNA BINDING; RNA CONFORMATION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; CIRCULAR DICHROISM; CLONING, MOLECULAR; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DROSOPHILA MELANOGASTER; HUMANS; METHYLATION; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NUCLEIC ACID CONFORMATION; PROTEIN CONFORMATION; RNA, TRANSFER; SEQUENCE ALIGNMENT;

EID: 84861894312     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi3002659     Document Type: Article

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