Comparison of the determination of a low-concentration active ingredient in pharmaceutical tablets by backscatter and transmission Raman spectrometry

Analytical Chemistry

Volumn 84, Issue 11, 2012, Pages 4671-4676

  Townshend, Nichola ^a   Nordon, Alison ^a   Littlejohn, David ^a   Myrick, Michael ^b   Andrews, John ^c   Dallin, Paul ^c  

^a UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^b UNIVERSITY OF SOUTH CAROLINA   (United States)

^c Moulton Park Industrial Estate   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ACCURATE PREDICTION; ACTIVE INGREDIENTS; ACTIVE PHARMACEUTICAL INGREDIENTS; CHLORPHENIRAMINE MALEATE; EXTERNAL CALIBRATION; HPLC ANALYSIS; LINEAR CALIBRATION; LOW CONCENTRATIONS; MICROCRYSTALLINE CELLULOSE; PARTICLE SIZE EFFECT; PHARMACEUTICAL PRODUCTS; PHARMACEUTICAL TABLETS; PHOTON PROPAGATION; RAMAN MEASUREMENTS; RAMAN SPECTROMETRIES; RELATIVE INTENSITY; SECOND DERIVATIVES; SPECTRAL NORMALIZATION;

BACKSCATTERING; DRUG PRODUCTS; PARTICLE SIZE; PHOTONS; SPECTROMETRY;

CALIBRATION;

CELLULOSE; CHLORPHENIRAMINE; EXCIPIENT; MICROCRYSTALLINE CELLULOSE;

ARTICLE; CALIBRATION; COMPARATIVE STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LASER; PARTICLE SIZE; RAMAN SPECTROMETRY; TABLET;

CALIBRATION; CELLULOSE; CHLORPHENIRAMINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EXCIPIENTS; LASERS; PARTICLE SIZE; SPECTRUM ANALYSIS, RAMAN; TABLETS;

EID: 84861891916     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac203447k     Document Type: Article

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