Aflatoxin-induced TP53 R249S mutation in hepatocellular carcinoma in thailand: Association with tumors developing in the absence of liver cirrhosis

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Villar, Stephanie ^a   Ortiz Cuaran, Sandra ^a   Abedi Ardekani, Behnoush ^a   Gouas, Doriane ^a   da Costa, Andre Nogueira ^a   Plymoth, Amelie ^b   Khuhaprema, Thiravud ^c   Kalalak, Anant ^c   Sangrajrang, Suleeporn ^c   Friesen, Marlin D ^d   Groopman, John D ^d   Hainaut, Pierre ^a,e  

^a INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

^b KAROLINSKA INSTITUTE   (Sweden)

^c NATIONAL CANCER INSTITUTE   (Thailand)

^d JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

^e INTERNATIONAL PREVENTION RESEARCH INSTITUTE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AFLATOXIN; ALPHA FETOPROTEIN; DNA; HEPATITIS B SURFACE ANTIGEN; HEPATITIS C ANTIBODY; PROTEIN P53;

ADULT; AGED; ANALYTIC METHOD; ARTICLE; BILE DUCT CARCINOMA; CASE CONTROL STUDY; CHRONIC LIVER DISEASE; CODON; CONTROLLED STUDY; DNA DETERMINATION; FEMALE; GENE DOSAGE; GENE MUTATION; GEOGRAPHIC DISTRIBUTION; HUMAN; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; ONCOGENE; PROTEIN BLOOD LEVEL; SHORT OLIGONUCLEOTIDE MASS ANALYSIS; TP53 GENE; AMINO ACID SUBSTITUTION; BLOOD; CELL TRANSFORMATION; CHEMICALLY INDUCED DISORDER; CHRONIC HEPATITIS; GENETICS; GEOGRAPHY; IMMUNOLOGY; LIVER TUMOR; METABOLISM; MIDDLE AGED; MUTATION; PATHOLOGY; THAILAND;

HEPATITIS B VIRUS;

ADULT; AFLATOXINS; AGED; ALPHA-FETOPROTEINS; AMINO ACID SUBSTITUTION; CARCINOMA, HEPATOCELLULAR; CELL TRANSFORMATION, NEOPLASTIC; DNA, NEOPLASM; FEMALE; GEOGRAPHY; HEPATITIS B SURFACE ANTIGENS; HEPATITIS C ANTIBODIES; HEPATITIS, CHRONIC; HUMANS; LIVER CIRRHOSIS; LIVER NEOPLASMS; MALE; MIDDLE AGED; MUTATION; THAILAND; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84861872186     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0037707     Document Type: Article

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