Study on synthesis of thalidomide analogues and their bioactivities; Inhibition on iNOS pathway and cytotoxic effects

Medicinal Chemistry Research

Volumn 21, Issue 7, 2012, Pages 953-963

  Yeh, Chao Bin ^a,b   Lin, Pen Yuan ^c   Hwang, Jin Ming ^a   Su, Chi Jung ^a   Yeh, Ying Tung ^a   Yang, Shun Fa ^a,b   Chou, Ming Chih ^a,b  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Nitric oxide synthase inhibitors; Thalidomide; Thalidomide analogues

Indexed keywords

2 ( 4 MERCAPTOPHENYL)ISOINDOLE 1,3 DIONE; 4 METHYL N (METHOXYLPHENYL)PHTHALIMIDE; 4 PHTHALIMIDO BENZONITRILE; AMINOBENZYLPHTHALIMIDE; ANTINEOPLASTIC AGENT; DIPHENYLAZOPHTHALIMIDE; INDUCIBLE NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE INHIBITOR; N ( 3 NITROPHENYL)PHTHALIMIDE; N ( 4 AMINOPHENYL) 1,8 NAPHTHALIMIDE; N ( 4 AMINOPHENYL)PHTHALIMIDE; N ( 4 AZOPHENYLPHENYL) 5 METHYLPHTHALIMIDE; N ( 4 BROMOPHENYL)PHTHALIMIDE; N ( 4 CHLOROPHENYL)PHTHALIMIDE; N ( 4 MERCAPTOPHENYL)PHTHALIMIDE; N ( 4 METHOXYPHENYL)PHTHALIMIDE; N ( 4 NITROPHENYL)PHTHALIMIDE; N ( 5 CHLORO 2 PYRIDYL)PHTHALIMIDE; N BIPHENYL 2 YL PHTHALIMIDE; N BIPHENYL 3,4 DIMETHYLMALEIMIDE; N BIPHENYL 4 YL PHTHALIMIDE; N PHENYLPHTHALIMIDE; N,N 2 PHENYLENE BIS PHTHALIMIDE; N,N 4 PHENYLENE BIS PHTHALIMIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR; PHTHALIMIDE DERIVATIVE; PYRIDYLPHTHALIMIDE; THALIDOMIDE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; ASIAN; CANCER CELL; CANCER CELL CULTURE; CARCINOMA CELL; CELL GROWTH; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG POTENCY; DRUG SYNTHESIS; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; LARYNX CARCINOMA; LEUKEMIA CELL; MYELOID LEUKEMIA; NASOPHARYNX CARCINOMA; NONHUMAN; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION;

EID: 84861860275     PISSN: 10542523     EISSN: 15548120     Source Type: Journal    
DOI: 10.1007/s00044-011-9603-7     Document Type: Article

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