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Volumn 31, Issue 2, 2012, Pages 166-174

Levosimendan does not improve cardiac output or blood pressure in a rodent model of propranolol toxicity when administered using various dosing regimens

Author keywords

animal study; levosimendan; overdose; poisoning; propranolol; toxicology

Indexed keywords

ADRENALIN; LEVOSIMENDAN; PROPRANOLOL;

EID: 84861852107     PISSN: 10915818     EISSN: 1092874X     Source Type: Journal    
DOI: 10.1177/1091581811435366     Document Type: Article
Times cited : (7)

References (28)
  • 1
    • 0041315449 scopus 로고    scopus 로고
    • Glucagon in β-blocker and calcium channel blocker overdoses: A systematic review
    • DOI 10.1081/CLT-120023761
    • Bailey B. Glucagon in β-blocker and calcium channel blocker overdoses: a systematic review. J Toxicol Clin Toxicol. 2003 ; 41 (5). 595-602 (Pubitemid 37102385)
    • (2003) Journal of Toxicology - Clinical Toxicology , vol.41 , Issue.5 , pp. 595-602
    • Bailey, B.1
  • 2
    • 33644884987 scopus 로고    scopus 로고
    • A comparison of vasopressin and glucagon in beta-blocker induced toxicity
    • DOI 10.1080/15563650500394795, PII T52KL1714332TX46
    • Holger J, Engebretsen K, Obetz C, Kleven T, Harris C. A comparison of vasopressin and glucagon in beta-blocker induced toxicity. Clin Toxicol. 2006 ; 44 (1). 45-51 (Pubitemid 44112963)
    • (2006) Clinical Toxicology , vol.44 , Issue.1 , pp. 45-51
    • Holger, J.1    Engebretsen, K.2    Obetz, C.3    Kleven, T.4    Harris, C.5
  • 4
    • 0025637170 scopus 로고
    • Glucagon in the management of deliberate self-poisoning with propranolol
    • Mansell PI. Glucagon in the management of deliberate self-poisoning with propranolol. Archiv Emerg Med. 1990 ; 7 (3). 238-240
    • (1990) Archiv Emerg Med , vol.7 , Issue.3 , pp. 238-240
    • Mansell, P.I.1
  • 5
    • 22544434099 scopus 로고    scopus 로고
    • The role of insulin and glucose (hyperinsulinaemia/euglycaemia) therapy in acute calcium channel antagonist and β-blocker poisoning
    • DOI 10.2165/00139709-200423040-00002
    • Megarbane B, Karyo S, Baud FJ. The role of insulin and glucose (hyperinsulinaemia/euglycaemia) therapy in acute calcium channel antagonist and (beta)-blocker poisoning. Toxicol Rev. 2004 ; 23 (4). 215-222 (Pubitemid 41018275)
    • (2004) Toxicological Reviews , vol.23 , Issue.4 , pp. 215-222
    • Megarbane, B.1    Karyo, S.2    Baud, F.J.3
  • 7
    • 14944348020 scopus 로고    scopus 로고
    • Comparison between dobutamine and levosimendan for management of postresuscitation myocardial dysfunction
    • DOI 10.1097/01.CCM.0000156241.55872.15
    • Huang L, Weil MH, Tang W, Sun S, Wang J. Comparison between dobutamine and levosimendan for management of postresuscitation myocardial dysfunction. Crit Care Med. 2005 ; 33 (3). 487-491 (Pubitemid 40365546)
    • (2005) Critical Care Medicine , vol.33 , Issue.3 , pp. 487-491
    • Huang, L.1    Weil, M.H.2    Tang, W.3    Sun, S.4    Wang, J.5
  • 8
    • 23944476671 scopus 로고    scopus 로고
    • Levosimendan: A calcium-sensitizing agent for the treatment of patients with decompensated heart failure
    • Lehtonen L. Levosimendan: a calcium-sensitizing agent for the treatment of patients with decompensated heart failure. Curr Heart Fail Rep. 2004 ; 1 (3). 136-144
    • (2004) Curr Heart Fail Rep , vol.1 , Issue.3 , pp. 136-144
    • Lehtonen, L.1
  • 9
    • 37649002347 scopus 로고    scopus 로고
    • Treatment of experimental verapamil poisoning with levosimendan utilizing a rodent model of drug toxicity
    • Graudins A, Najafi J, Rur-Sc MPM. Treatment of experimental verapamil poisoning with levosimendan utilizing a rodent model of drug toxicity. Clin Toxicol. 2008 ; 46 (1). 50-56
    • (2008) Clin Toxicol , vol.46 , Issue.1 , pp. 50-56
    • Graudins, A.1    Najafi, J.2    Rur-Sc, M.P.M.3
  • 10
    • 77951260466 scopus 로고    scopus 로고
    • Norepinephrine co-administered with levosimendan does not reverse hypotension in a rodent model experimental verapamil poisoning [abstract]
    • Najafi JM, Graudins A. Norepinephrine co-administered with levosimendan does not reverse hypotension in a rodent model experimental verapamil poisoning [abstract]. Emerg Med Australas. 2007 ; 19 (suppl1). A19 - A20
    • (2007) Emerg Med Australas , vol.19 , Issue.SUPPL.1
    • Najafi, J.M.1    Graudins, A.2
  • 11
    • 77956183820 scopus 로고    scopus 로고
    • Comparative hemodynamic effects of levosimendan alone and in conjunction with 4-aminopyridine or calcium chloride in a rodent model of severe Verapamil poisoning
    • Graudins A, Wong KKL. Comparative hemodynamic effects of levosimendan alone and in conjunction with 4-aminopyridine or calcium chloride in a rodent model of severe Verapamil poisoning. J Med Toxicol. 2010 ; 6 (2). 85-93
    • (2010) J Med Toxicol , vol.6 , Issue.2 , pp. 85-93
    • Graudins, A.1    Wong, K.K.L.2
  • 12
    • 77949449211 scopus 로고    scopus 로고
    • Effect of levosimendan in experimental verapamil-induced myocardial depression
    • Kurola J, Leppikangas H, Magga J, et al. Effect of levosimendan in experimental verapamil-induced myocardial depression. Scand J Trauma Resusc Emerg Med. 2010 ; 18: 12
    • (2010) Scand J Trauma Resusc Emerg Med , vol.18 , pp. 12
    • Kurola, J.1    Leppikangas, H.2    Magga, J.3
  • 13
    • 70449703291 scopus 로고    scopus 로고
    • Levosimendan as a rescue drug in experimental propranolol-induced myocardial depression: A randomized study
    • Leppikangas H, Ruokonen E, Rutanen J, Kiviniemi V, Lindgren L, Kurola J. Levosimendan as a rescue drug in experimental propranolol-induced myocardial depression: a randomized study. Ann Emerg Med. 2009 ; 54 (6). 811-817
    • (2009) Ann Emerg Med , vol.54 , Issue.6 , pp. 811-817
    • Leppikangas, H.1    Ruokonen, E.2    Rutanen, J.3    Kiviniemi, V.4    Lindgren, L.5    Kurola, J.6
  • 14
    • 77951929073 scopus 로고    scopus 로고
    • In response to Leppikangas H, et al, Levosimendan as a rescue drug in experimental propranolol-induced myocardial depression: A randomized study
    • Lugassy DM, Stefan A, Dexeus D, Hoffman RS, Nelson LS. In response to Leppikangas H, et al, Levosimendan as a rescue drug in experimental propranolol-induced myocardial depression: a randomized study. Ann Emerg Med. 2010 ; 55 (5). 486
    • (2010) Ann Emerg Med , vol.55 , Issue.5 , pp. 486
    • Lugassy, D.M.1    Stefan, A.2    Dexeus, D.3    Hoffman, R.S.4    Nelson, L.S.5
  • 15
    • 84861918836 scopus 로고    scopus 로고
    • Levosimendan infusion improves cardiac output but not blood pressure in a rodent model of severe metoprolol toxicity
    • Kalam Y, Graudins A. Levosimendan infusion improves cardiac output but not blood pressure in a rodent model of severe metoprolol toxicity. Hum Exp Toxicol. 2012 ;.
    • (2012) Hum Exp Toxicol
    • Kalam, Y.1    Graudins, A.2
  • 16
    • 0024415909 scopus 로고
    • Alterations in distribution of cardiac output in experimental diabetes in rats
    • Hill MA, Larkins RG. Alterations in distribution of cardiac output in experimental diabetes in rats. Am J Physiol Heart Circ Physiol. 1989 ; 257 (2). 26
    • (1989) Am J Physiol Heart Circ Physiol , vol.257 , Issue.2 , pp. 26
    • Ma, H.1    Larkins, R.G.2
  • 18
    • 34247609797 scopus 로고    scopus 로고
    • Management of (beta)-adrenergic blocker and calcium channel antagonist toxicity
    • Kerns Ii W. Management of (beta)-adrenergic blocker and calcium channel antagonist toxicity. Emerg Med Clin North Am. 2007 ; 25 (2). 309-331
    • (2007) Emerg Med Clin North Am , vol.25 , Issue.2 , pp. 309-331
    • Kerns Ii, W.1
  • 19
    • 0035025145 scopus 로고    scopus 로고
    • Levosimendan: Aparenteralcalcium- sensitisingdrugwithadditionalvasodilatoryproperties
    • Lehtonen LA.. Levosimendan: aparenteralcalcium- sensitisingdrugwithadditionalvasodilatoryproperties. Expert Opin Investig Drugs. 2001 ; 10 (5). 955-970
    • (2001) Expert Opin Investig Drugs , vol.10 , Issue.5 , pp. 955-970
    • Lehtonen, L.A.1
  • 20
    • 85001095424 scopus 로고    scopus 로고
    • Levosimendan as treatment option in severe verapamil intoxication: A case report and review of the literature
    • Osthoff M, Bernsmeier C, Marsch SC, Hunziker PR. Levosimendan as treatment option in severe verapamil intoxication: a case report and review of the literature. Case Report Med. 2010 ; 2010.
    • (2010) Case Report Med , vol.2010
    • Osthoff, M.1    Bernsmeier, C.2    Marsch, S.C.3    Hunziker, P.R.4
  • 21
    • 61949220687 scopus 로고    scopus 로고
    • Treatment of serious calcium channel blocker overdose with levosimendan, a calcium sensitizer
    • Varpula T. Treatment of serious calcium channel blocker overdose with levosimendan, a calcium sensitizer. Anesth Analg. 2009 ; 108 (3). 790-792
    • (2009) Anesth Analg , vol.108 , Issue.3 , pp. 790-792
    • Varpula, T.1
  • 22
    • 0141724848 scopus 로고    scopus 로고
    • Levosimendan compared with dobutamine in low output patients
    • Nieminen MS. Levosimendan compared with dobutamine in low output patients. Minerva Anesthesiol. 2003 ; 69 (4). 258-263 (Pubitemid 41750911)
    • (2003) Minerva Anestesiologica , vol.69 , Issue.4 , pp. 258-263
    • Nieminen, M.S.1
  • 23
    • 0018566140 scopus 로고
    • Clinical pharmacology of the new beta-adrenergic blocking drugs. Part 2. Physiologic and metabolic effects
    • DOI 10.1016/0002-8703(79)90016-4
    • Frishman W, Silverman R. Clinical pharmacology of the new beta-adrenergic blocking drugs. Part 2. Physiologic and metabolic effects. Am Heart J. 1979 ; 97 (6). 797-807 (Pubitemid 10180449)
    • (1979) American Heart Journal , vol.97 , Issue.6 , pp. 797-807
    • Frishman, W.1    Silverman, R.2
  • 24
    • 0022494818 scopus 로고
    • Experimental amitriptyline intoxication: Treatment of cardiac toxicity with sodium bicarbonate
    • Sasyniuk BI, Jhamandas V, Valois M. Experimental amitriptylline intoxication: treatment of cardiac toxicity with sodium bicarbonate. Ann Emerg Med. 1986 ; 15 (9). 1052-1059 (Pubitemid 16017764)
    • (1986) Annals of Emergency Medicine , vol.15 , Issue.9 , pp. 1052-1059
    • Sasyniuk, B.I.1    Jhamandas, V.2    Valois, M.3
  • 25
    • 0021223468 scopus 로고
    • Efficacy and mechanism of action of sodium bicarbonate in the treatment of desipramine toxicity in rats
    • Pentel P, Benowitz N. Efficacy and mechanism of action of sodium bicarbonate in the treatment of desipramine toxicity in rats. J Pharmacol Exp Ther. 1984 ; 230 (1). 12-19 (Pubitemid 14097652)
    • (1984) Journal of Pharmacology and Experimental Therapeutics , vol.230 , Issue.1 , pp. 12-19
    • Pentel, P.1    Benowitz, N.2
  • 26
    • 2342425037 scopus 로고    scopus 로고
    • Levosimendan: First in a new class of inodilator for acute and chronic severe heart failure
    • DOI 10.1586/14779072.2.1.9
    • Cleland JGF. Levosimendan: first in a new class of inodilator for acute and chronic severe heart failure. Expert Rev Cardiovasc Ther. 2004 ; 2 (1). 9-19 (Pubitemid 38678754)
    • (2004) Expert Review of Cardiovascular Therapy , vol.2 , Issue.1 , pp. 9-19
    • Cleland, J.G.F.1    Nikitin, N.2    McGowan, J.3
  • 27
    • 27344446541 scopus 로고    scopus 로고
    • Levosimendan: A novel inotropic agent for treatment of acute, decompensated heart failure
    • DOI 10.1345/aph.1G128
    • Earl G. Levosimendan: a novel inotropic agent for treatment of acute, decompensated heart failure. Ann Pharmacother. 2005 ; 39 (11). 1888-1896 (Pubitemid 41527702)
    • (2005) Annals of Pharmacotherapy , vol.39 , Issue.11 , pp. 1888-1896
    • Earl, G.L.1    Fitzpatrick, J.T.2
  • 28
    • 0018096305 scopus 로고
    • Comparative stability of physiological parameters during sustained anesthesia in rats
    • Buelke Sam J, Holson JF, Bazare JJ, Young JF. Comparative stability of physiological parameters during sustained anesthesia in rats. Lab Anim Sci. 1978 ; 28 (2). 157-162 (Pubitemid 8343548)
    • (1978) Laboratory Animal Science , vol.28 , Issue.2 , pp. 157-162
    • Buelke-Sam, J.1    Holson, J.F.2    Bazare, J.J.3    Young, J.F.4


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