A comparison of vasopressin and glucagon in beta-blocker induced toxicity

Clinical Toxicology

Volumn 44, Issue 1, 2006, Pages 45-51

  Holger, Joel ^a   Engebretsen, Kristin ^a   Obetz, Christopher ^a,b   Kleven, Tanya ^a   Harris, Carson ^a  

^a REGIONS HOSPITAL   (United States)

^b ABBOTT NORTHWESTERN HOSPITAL   (United States)

Author keywords

blockers; Glucagon; Overdose; Poisoning; Vasopressin

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; GLUCAGON; GLUCOSE; PROPRANOLOL; SODIUM CHLORIDE; VASOPRESSIN; VASOCONSTRICTOR AGENT; VASOPRESSIN DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DEATH; DRUG INTOXICATION; GLUCOSE BLOOD LEVEL; HEART OUTPUT; HEART RATE; KAPLAN MEIER METHOD; LOG RANK TEST; MEAN ARTERIAL PRESSURE; NONHUMAN; PH; PROSPECTIVE STUDY; RANDOMIZATION; RESUSCITATION; STATISTICAL SIGNIFICANCE; SURVIVAL; SWINE; SYSTOLIC BLOOD PRESSURE; TREATMENT OUTCOME; ANIMAL; BLOOD PRESSURE; COMPARATIVE STUDY; DISEASE MODEL; DRUG EFFECT; HEMODYNAMICS; INTOXICATION; MORTALITY; PATHOPHYSIOLOGY; SURVIVAL RATE;

SUIDAE; SUS SCROFA;

ADRENERGIC BETA-ANTAGONISTS; ANIMALS; BLOOD PRESSURE; DISEASE MODELS, ANIMAL; GLUCAGON; HEART RATE; HEMODYNAMIC PROCESSES; POISONING; PROPRANOLOL; SURVIVAL RATE; SWINE; VASOCONSTRICTOR AGENTS; VASOPRESSINS;

EID: 33644884987     PISSN: 15563650     EISSN: 15569519     Source Type: Journal    
DOI: 10.1080/15563650500394795     Document Type: Article

References (31)

1. Watson WA, Litovitz TL, Klein-Schwartz W, Rodgers GC Jr, Youniss J, Reid N, Rouse WG, Rembert RS, Borys D. 2003 annual report of the American Association of Poison Control Centers Toxic Exposure Surveillance System. Am J Emerg Med 2004; 22(5):335-404.
2. Howland MA. Glucagon. In: Goldfrank's Toxicologic Emergencies. 7th ed. New York: McGraw-Hill, 2002:758-761.
3. Ellenhorn MJ. Ellenhorn's Medical Toxicology. 2nd ed. Baltimore: Williams and Wilkins, 1997.
4. Freestone S, Thomas HM, Bhamra RK, Dyson EH. Severe atenolol poisoning: treatment with prenalterol. Hum Toxicol 1986; 5(5):343-5.
5. Hurwitz MD, Kallenbach JM, Pincus PS. Massive propranolol overdose. Am J Med 1986; 81(6):1118.
6. Shore ET, Cepin D, Davidson MJ. Metoprolol overdose. Ann Emerg Med 1981; 10(10):524-7.
7. Schrier RW, Berl T, Anderson RJ. Osmotic and nonosmotic control of vasopressin release. Am J Physiol 1979; 236(4):F321-32.
8. Wakatsuki T, Nakaya Y, Inoue I. Vasopressin modulates K(+)-channel activities of cultured smooth muscle cells from porcine coronary artery. Am J Physiol 1992; 263 (2 Pt 2):H491-6.
9. Reid IA. Role of vasopressin deficiency in the vasodilation of septic shock. Circulation 1997; 95(5):1108-10.
10. Cowley AW Jr, Monos E, Guyton AC. Interaction of vasopressin and the baroreceptor reflex system in the regulation of arterial blood pressure in the dog. Circ Res 1974; 34(4):505-14.
11. Rozenfeld V, Cheng JW. The role of vasopressin in the treatment of vasodilation in shock states. Ann Pharmacother 2000; 34(2):250-4.
12. Landry DW, Levin HR, Gallant EM, Ashton RC, Seo S Jr, D'Alessandro D, Oz MC, Oliver JA. Vasopressin deficiency contributes to the vasodilation of septic shock. Circulation 1997; 95(5):1122-5.
13. Holstege CP, Hunter Y, Baer AB, Savory J, Brans DE, Boyd JC. Massive caffeine overdose requiring vasopressin infusion and hemodialysis. J Toxicol Clin Toxicol 2003; 41(7):1003-7.
14. Barry JD, Durkovich DW, Williams SR. Vasopressin for hypotension in severe amitriptyline poisoning. North American Congress of Clinical Toxicology Annual Meeting; Palm Springs, CA, Sept. 24-29, 2002; J Toxicol Clin Toxicol; 40(5):622.
15. Baer AB, Holstege CP. Milrinone overdose induced hypotension reversed by vasopressin and norepinephrine infusions. North American Congress of Clinical Toxicology Annual Meeting; Palm Springs, CA, Sept. 24-29, 2002; J Toxicol Clin Toxicol; 40(5):690.
16. Lindner KH, Brinkmann A, Pfenninger EG, Lurie KG, Goertz A, Lindner IM. Effect of vasopressin on hemodynamic variables, organ blood flow, and acid-base status in a pig model of cardiopulmonary resuscitation. Anesth Analg 1993; 77(3):427-35.
17. Wenzel V, Lindner KH, Krismer AC, Miller EA, Voelckel WG, Lingnau W. Repeated administration of vasopressin but not epinephrine maintains coronary perfusion pressure after early and late administration during prolonged cardiopulmonary resuscitation in pigs. Circulation 1999; 99(10):1379-84.
18. Kerns W, Schroeder D, Williams C, Tomaszewski C, Raymond R. Insulin improves survival in a canine model of acute beta-blocker toxicity.. Ann Emerg Med 1997; 29(6):748-57.
19. Brubacher JR. Beta-Adrenergic Antagonists. In: Goldfrank's Toxicologic Emergencies. 7th ed. New York: McGraw-Hill, 2002:741-761.
20. Kerns W. Beta-andrenergic repeptor antagonists. Clinical Toxicology. Philadelphia: WB Saunders Company, 2001:362-369.
21. Bailey B. Glucagon in beta-blocker and calcium channel blocker overdoses: a systematic review. J Toxicol Clin Toxicol 2003; 41(5):595-602.
22. Stiell IG, Hebert PC, Wells GA, Vandemheen KL, Tang AS, Higginson LA, Dreyer JF, Clement C, Battram E, Watpool I, Mason S, Klassen T, Weitzman BN. Vasopressin versus epinephrine for inhospital cardiac arrest: a randomised controlled trial. Lancet 2001; 358(9276):105-9.
23. Wenzel V, Krismer AC, Arntz HR, Sitter H, Stadibauer KH, Lindner KH. A comparison of vasopressin and epinephrine for out-of-hospital cardiopulmonary resuscitation. N Engl J Med 2004; 350(2):105-13.
24. Barry JD, Durkovitch DW, Richardson WH, Tong TC, Cantrell FL, Offerman SR, Clark RF, Tanen DA, Williams SR. Vasopressin treatment of verapamil toxicity in the porcine model. North American Congress of Clincal Toxicology Annual Meeting; Chicago, IL, Sept. 4-9, 2003; J Toxicol Clin Toxicol; 41(5):694.
25. Holmes CL, Patel BM, Russell JA, Walley KR. Physiology of vasopressin relevant to management of septic shock. Chest 2001; 120(3):989-1002.
26. Lindner KH, Strohmenger HU, Ensinger H, Hetzel WD, Ahnefeld FW, Georgieff M. Stress hormone response during and after cardiopulmonary resuscitation. Anesthesiology 1992; 77(4):662-8.
27. Mayr VD, Wenzel V, Voelckel WG, Krismer AC, Mueller T, Lurie KG, Lindner KH. Developing a vasopressor combination in a pig model of adult asphyxial cardiac arrest. Circulation 2001; 104(14):1651-6.
28. Noguera I, Medina P, Segarra G, Martinez MC, Aldasoro M, Vila JM, Lluch S. Potentiation by vasopressin of adrenergic vasoconstriction in the rat isolated mesenteric artery. Br J Pharmacol 1997; 122(3):431-8.
29. Segarra G, Medina P, Domenech C, Vila JM, Martinez-Leon JB, Aldasoro M, Lluch S. Role of vasopressin on adrenergic neurotransmission in human penile blood vessels. J Pharmacol Exp Ther 1998; 286(3):1315-20.
30. Paradis NA, Rose MI, Garg U. The effect of global ischemia and reperfusion on the plasma levels of vasoactive peptides. The neuroendocrine response to cardiac arrest and resuscitation. Resuscitation. 1993; 26(3):261-9.
31. Sztajnkrycer MD, Bond GR, Johnson SB, Weaver AL. Use of vasopressin in a canine model of severe verapamil poisoning: a preliminary descriptive study. Acad Emerg Med 2004; 11(12):1253-61.