-
1
-
-
79960016921
-
Type 2 diabetes and obesity: Genomics and the clinic
-
Travers ME, McCarthy MI. Type 2 diabetes and obesity: genomics and the clinic. Hum. Genet., 130, 41-58 (2011).
-
(2011)
Hum. Genet.
, vol.130
, pp. 41-58
-
-
Travers, M.E.1
McCarthy, M.I.2
-
2
-
-
38849099617
-
Genetics of type 2 diabetes mellitus and obesity-a review
-
Jafar-Mohammadi B, McCarthy MI. Genetics of type 2 diabetes mellitus and obesity-a review. Ann. Med., 40, 2-10 (2008).
-
(2008)
Ann. Med.
, vol.40
, pp. 2-10
-
-
Jafar-Mohammadi, B.1
McCarthy, M.I.2
-
3
-
-
77955274518
-
PPARgamma in adipocyte differentiation and metabolism-novel insights from genome-wide studies
-
Siersbaek R, Nielsen R, Mandrup S. PPARgamma in adipocyte differentiation and metabolism-novel insights from genome-wide studies. FEBS Lett., 584, 3242-3249 (2010).
-
(2010)
FEBS Lett.
, vol.584
, pp. 3242-3249
-
-
Siersbaek, R.1
Nielsen, R.2
Mandrup, S.3
-
4
-
-
0036651772
-
PPAR family (PPAR alpha, PPAR delta, PPAR gamma)
-
Kamon J, Yamauchi T, Kadowaki T. PPAR family (PPAR alpha, PPAR delta, PPAR gamma). Nippon Rinsho, 60 (Suppl. 7), 593-600 (2002).
-
(2002)
Nippon Rinsho
, vol.60
, Issue.SUPPL. 7
, pp. 593-600
-
-
Kamon, J.1
Yamauchi, T.2
Kadowaki, T.3
-
5
-
-
0030679687
-
PPAR gamma and the molecular control of adipogenesis
-
Brun RP, Spiegelman BM. PPAR gamma and the molecular control of adipogenesis. J. Endocrinol., 155, 217-218 (1997).
-
(1997)
J. Endocrinol.
, vol.155
, pp. 217-218
-
-
Brun, R.P.1
Spiegelman, B.M.2
-
6
-
-
28944446431
-
The many faces of PPARgamma
-
Lehrke M, Lazar MA. The many faces of PPARgamma. Cell, 123, 993-999 (2005).
-
(2005)
Cell
, vol.123
, pp. 993-999
-
-
Lehrke, M.1
Lazar, M.A.2
-
7
-
-
55749105417
-
Adipokines and insulin resistance
-
Rabe K, Lehrke M, Parhofer KG, Broedl UC. Adipokines and insulin resistance. Mol. Med., 14, 741-751 (2008).
-
(2008)
Mol. Med.
, vol.14
, pp. 741-751
-
-
Rabe, K.1
Lehrke, M.2
Parhofer, K.G.3
Broedl, U.C.4
-
8
-
-
16544393025
-
Review: Peroxisome proliferator-activated receptor-gamma and its role in the development and treatment of diabetes
-
Leff T, Mathews ST, Camp HS. Review: peroxisome proliferator-activated receptor-gamma and its role in the development and treatment of diabetes. Exp. Diabesity Res., 5, 99-109 (2004).
-
(2004)
Exp. Diabesity Res.
, vol.5
, pp. 99-109
-
-
Leff, T.1
Mathews, S.T.2
Camp, H.S.3
-
9
-
-
0033599038
-
Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension
-
Barroso I, Gurnell M, Crowley VE, Agostini M, Schwabe JW, Soos MA, Maslen GL, Williams TD, Lewis H, Schafer AJ, Chatterjee VK, O'Rahilly S. Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension. Nature, 402, 880-883 (1999).
-
(1999)
Nature
, vol.402
, pp. 880-883
-
-
Barroso, I.1
Gurnell, M.2
Crowley, V.E.3
Agostini, M.4
Schwabe, J.W.5
Soos, M.A.6
Maslen, G.L.7
Williams, T.D.8
Lewis, H.9
Schafer, A.J.10
Chatterjee, V.K.11
O'Rahilly, S.12
-
10
-
-
10644262362
-
Cardiovascular risk in type 2 diabetes is associated with variation at the PPARG locus: A Go-DARTS study
-
Doney AS, Fischer B, Leese G, Morris AD, Palmer CN. Cardiovascular risk in type 2 diabetes is associated with variation at the PPARG locus: a Go-DARTS study. Arterioscler. Thromb. Vasc. Biol., 24, 2403-2407 (2004).
-
(2004)
Arterioscler. Thromb. Vasc. Biol.
, vol.24
, pp. 2403-2407
-
-
Doney, A.S.1
Fischer, B.2
Leese, G.3
Morris, A.D.4
Palmer, C.N.5
-
11
-
-
34249852935
-
Familial partial lipodystrophy phenotype resulting from a single-base mutation in deoxyribonucleic acid-binding domain of peroxisome proliferator-activated receptor-gamma
-
Monajemi H, Zhang L, Li G, Jeninga EH, Cao H, Maas M, Brouwer CB, Kalkhoven E, Stroes E, Hegele RA, Leff T. Familial partial lipodystrophy phenotype resulting from a single-base mutation in deoxyribonucleic acid-binding domain of peroxisome proliferator-activated receptor-gamma. J. Clin. Endocrinol. Metab., 92, 1606-1612 (2007).
-
(2007)
J. Clin. Endocrinol. Metab.
, vol.92
, pp. 1606-1612
-
-
Monajemi, H.1
Zhang, L.2
Li, G.3
Jeninga, E.H.4
Cao, H.5
Maas, M.6
Brouwer, C.B.7
Kalkhoven, E.8
Stroes, E.9
Hegele, R.A.10
Leff, T.11
-
13
-
-
23644456172
-
Therapeutic roles of peroxisome proliferator-activated receptor agonists
-
Staels B, Fruchart JC. Therapeutic roles of peroxisome proliferator-activated receptor agonists. Diabetes, 54, 2460-2470 (2005).
-
(2005)
Diabetes
, vol.54
, pp. 2460-2470
-
-
Staels, B.1
Fruchart, J.C.2
-
14
-
-
29844443744
-
Ginsenoside 20Sprotopanaxatriol (PPT) activates peroxisome proliferator-activated receptor gamma (PPARgamma) in 3T3-L1 adipocytes
-
Han KL, Jung MH, Sohn JH, Hwang JK. Ginsenoside 20Sprotopanaxatriol (PPT) activates peroxisome proliferator-activated receptor gamma (PPARgamma) in 3T3-L1 adipocytes. Biol. Pharm. Bull., 29, 110-113 (2006).
-
(2006)
Biol. Pharm. Bull.
, vol.29
, pp. 110-113
-
-
Han, K.L.1
Jung, M.H.2
Sohn, J.H.3
Hwang, J.K.4
-
15
-
-
79952573418
-
Artepillin C, as a PPARγ ligand, enhances adipocyte differentiation and glucose uptake in 3T3-L1 cells
-
Choi SS, Cha BY, Iida K, Lee YS, Yonezawa T, Teruya T, Nagai K, Woo JT. Artepillin C, as a PPARγ ligand, enhances adipocyte differentiation and glucose uptake in 3T3-L1 cells. Biochem. Pharmacol., 81, 925-933 (2011).
-
(2011)
Biochem. Pharmacol.
, vol.81
, pp. 925-933
-
-
Choi, S.S.1
Cha, B.Y.2
Iida, K.3
Lee, Y.S.4
Yonezawa, T.5
Teruya, T.6
Nagai, K.7
Woo, J.T.8
-
16
-
-
33845723280
-
Emodin with PPARgamma ligand-binding activity promotes adipocyte differentiation and increases glucose uptake in 3T3-Ll cells
-
Yang Y, Shang W, Zhou L, Jiang B, Jin H, Chen M. Emodin with PPARgamma ligand-binding activity promotes adipocyte differentiation and increases glucose uptake in 3T3-Ll cells. Biochem. Biophys. Res. Commun., 353, 225-230 (2007).
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.353
, pp. 225-230
-
-
Yang, Y.1
Shang, W.2
Zhou, L.3
Jiang, B.4
Jin, H.5
Chen, M.6
-
17
-
-
56649109706
-
-Catechin promotes adipocyte differentiation in human bone marrow mesenchymal stem cells through PPAR gamma transactivation
-
Shin DW, Kim SN, Lee SM, Lee W, Song MJ, Park SM, Lee TR, Baik JH, Kim HK, Hong JH, Noh M. (-)-Catechin promotes adipocyte differentiation in human bone marrow mesenchymal stem cells through PPAR gamma transactivation. Biochem. Pharmacol., 77, 125-133 (2009).
-
(2009)
Biochem. Pharmacol.
, vol.77
, pp. 125-133
-
-
Shin, D.W.1
Kim, S.N.2
Lee, S.M.3
Lee, W.4
Song, M.J.5
Park, S.M.6
Lee, T.R.7
Baik, J.H.8
Kim, H.K.9
Hong, J.H.10
Noh, M.11
-
18
-
-
67349146720
-
Magnolol enhances adipocyte differentiation and glucose uptake in 3T3-L1 cells
-
Choi SS, Cha BY, Lee YS, Yonezawa T, Teruya T, Nagai K, Woo JT. Magnolol enhances adipocyte differentiation and glucose uptake in 3T3-L1 cells. Life Sci., 84, 908-914 (2009).
-
(2009)
Life Sci.
, vol.84
, pp. 908-914
-
-
Choi, S.S.1
Cha, B.Y.2
Lee, Y.S.3
Yonezawa, T.4
Teruya, T.5
Nagai, K.6
Woo, J.T.7
-
19
-
-
33746093280
-
Tumor inhibition and improved immunity in mice treated with flavone from Cirsium japonicum DC
-
Liu SJ, Luo X, Li DX, Zhang J, Qiu DL, Liu W, She L, Yang ZR. Tumor inhibition and improved immunity in mice treated with flavone from Cirsium japonicum DC. Int. Immunopharmacol., 6, 1387-1393 (2006).
-
(2006)
Int. Immunopharmacol.
, vol.6
, pp. 1387-1393
-
-
Liu, S.J.1
Luo, X.2
Li, D.X.3
Zhang, J.4
Qiu, D.L.5
Liu, W.6
She, L.7
Yang, Z.R.8
-
20
-
-
40349113379
-
Comparative antioxidant activity and HPLC profiles of some selected Korean thistles
-
Jeong M, Jung HA, Choi JS. Comparative antioxidant activity and HPLC profiles of some selected Korean thistles. Arch. Pharm. Res., 31, 28-33 (2008).
-
(2008)
Arch. Pharm. Res.
, vol.31
, pp. 28-33
-
-
Jeong, M.1
Jung, H.A.2
Choi, J.S.3
-
21
-
-
79959305766
-
Antioxidant and antidiabetic activities of extracts from Cirsium japonicum roots
-
Yin J, Heo SI, Wang MH. Antioxidant and antidiabetic activities of extracts from Cirsium japonicum roots. Nutr. Res. Pract., 2, 247-251 (2008).
-
(2008)
Nutr. Res. Pract.
, vol.2
, pp. 247-251
-
-
Yin, J.1
Heo, S.I.2
Wang, M.H.3
-
22
-
-
77953643313
-
Antidiabetic effect of flavones from Cirsium japonicum DC in diabetic rats
-
Liao ZY, Chen XL, Wu MJ. Antidiabetic effect of flavones from Cirsium japonicum DC in diabetic rats. Arch. Pharm. Res., 33, 353-362 (2010).
-
(2010)
Arch. Pharm. Res.
, vol.33
, pp. 353-362
-
-
Liao, Z.Y.1
Chen, X.L.2
Wu, M.J.3
-
23
-
-
0031898610
-
PPAR-gamma: Adipogenic regulator and thiazolidinedione receptor
-
Spiegelman BM. PPAR-gamma: adipogenic regulator and thiazolidinedione receptor. Diabetes, 47, 507-514 (1998).
-
(1998)
Diabetes
, vol.47
, pp. 507-514
-
-
Spiegelman, B.M.1
-
24
-
-
0029806069
-
Troglitazone enhances differentiation, basal glucose uptake, and Glut1 protein levels in 3T3-L1 adipocytes
-
Tafuri SR. Troglitazone enhances differentiation, basal glucose uptake, and Glut1 protein levels in 3T3-L1 adipocytes. Endocrinology, 137, 4706-4712 (1996).
-
(1996)
Endocrinology
, vol.137
, pp. 4706-4712
-
-
Tafuri, S.R.1
-
25
-
-
0036434431
-
Insulin regulation of glucose uptake: A complex interplay of intracellular signalling pathways
-
Khan AH, Pessin JE. Insulin regulation of glucose uptake: a complex interplay of intracellular signalling pathways. Diabetologia, 45, 1475-1483 (2002).
-
(2002)
Diabetologia
, vol.45
, pp. 1475-1483
-
-
Khan, A.H.1
Pessin, J.E.2
-
26
-
-
1842454705
-
Adipose tissue and adipokines: For better or worse
-
Guerre-Millo M. Adipose tissue and adipokines: for better or worse. Diabetes Metab., 30, 13-19 (2004).
-
(2004)
Diabetes Metab.
, vol.30
, pp. 13-19
-
-
Guerre-Millo, M.1
-
27
-
-
0035798713
-
The mechanisms by which both heterozygous peroxisome proliferator- activated receptor gamma (PPARgamma) deficiency and PPARgamma agonist improve insulin resistance
-
Yamauchi T, Kamon J, Waki H, Murakami K, Motojima K, Komeda K, Ide T, Kubota N, Terauchi Y, Tobe K, Miki H, Tsuchida A, Akanuma Y, Nagai R, Kimura S, Kadowaki T. The mechanisms by which both heterozygous peroxisome proliferator-activated receptor gamma (PPARgamma) deficiency and PPARgamma agonist improve insulin resistance. J. Biol. Chem., 276, 41245-41254 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 41245-41254
-
-
Yamauchi, T.1
Kamon, J.2
Waki, H.3
Murakami, K.4
Motojima, K.5
Komeda, K.6
Ide, T.7
Kubota, N.8
Terauchi, Y.9
Tobe, K.10
Miki, H.11
Tsuchida, A.12
Akanuma, Y.13
Nagai, R.14
Kimura, S.15
Kadowaki, T.16
-
28
-
-
58149170595
-
Improved insulin resistance and lipid metabolism by cinnamon extract through activation of peroxisome proliferator-activated receptors
-
Sheng X, Zhang Y, Gong Z, Huang C, Zang YQ. Improved insulin resistance and lipid metabolism by cinnamon extract through activation of peroxisome proliferator-activated receptors. PPAR Res., 2008, 581348 (2008).
-
(2008)
PPAR Res.
, vol.2008
, pp. 581348
-
-
Sheng, X.1
Zhang, Y.2
Gong, Z.3
Huang, C.4
Zang, Y.Q.5
-
29
-
-
0035430576
-
Effects of pioglitazone on adipose tissue remodeling within the setting of obesity and insulin resistance
-
de Souza CJ, Eckhardt M, Gagen K, Dong M, Chen W, Laurent D, Burkey BF. Effects of pioglitazone on adipose tissue remodeling within the setting of obesity and insulin resistance. Diabetes, 50, 1863-1871 (2001).
-
(2001)
Diabetes
, vol.50
, pp. 1863-1871
-
-
De Souza, C.J.1
Eckhardt, M.2
Gagen, K.3
Dong, M.4
Chen, W.5
Laurent, D.6
Burkey, B.F.7
-
30
-
-
65249159076
-
Peroxisome proliferator-activated receptor gamma ligands isolated from adlay seed (Coix lacryma-jobi L. var. ma-yuen STAPF.)
-
Yokoi H, Mizukami H, Nagatsu A, Ohno T, Tanabe H, Inoue M. Peroxisome proliferator-activated receptor gamma ligands isolated from adlay seed (Coix lacryma-jobi L. var. ma-yuen STAPF.). Biol. Pharm. Bull., 32, 735-740 (2009).
-
(2009)
Biol. Pharm. Bull.
, vol.32
, pp. 735-740
-
-
Yokoi, H.1
Mizukami, H.2
Nagatsu, A.3
Ohno, T.4
Tanabe, H.5
Inoue, M.6
-
31
-
-
77957571019
-
7-O-methylaromadendrin stimulates glucose uptake and improves insulin resistance in vitro
-
Zhang WY, Lee JJ, Kim IS, Kim Y, Park JS, Myung CS. 7-O- methylaromadendrin stimulates glucose uptake and improves insulin resistance in vitro. Biol. Pharm. Bull., 33, 1494-1499 (2010).
-
(2010)
Biol. Pharm. Bull.
, vol.33
, pp. 1494-1499
-
-
Zhang, W.Y.1
Lee, J.J.2
Kim, I.S.3
Kim, Y.4
Park, J.S.5
Myung, C.S.6
-
32
-
-
0033515761
-
Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity
-
Arita Y, Kihara S, Ouchi N, Takahashi M, Maeda K, Miyagawa J, Hotta K, Shimomura I, Nakamura T, Miyaoka K, Kuriyama H, Nishida M, Yamashita S, Okubo K, Matsubara K, Muraguchi M, Ohmoto Y, Funahashi T, Matsuzawa Y. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem. Biophys. Res. Commun., 257, 79-83 (1999).
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.257
, pp. 79-83
-
-
Arita, Y.1
Kihara, S.2
Ouchi, N.3
Takahashi, M.4
Maeda, K.5
Miyagawa, J.6
Hotta, K.7
Shimomura, I.8
Nakamura, T.9
Miyaoka, K.10
Kuriyama, H.11
Nishida, M.12
Yamashita, S.13
Okubo, K.14
Matsubara, K.15
Muraguchi, M.16
Ohmoto, Y.17
Funahashi, T.18
Matsuzawa, Y.19
-
33
-
-
67650169799
-
Adiponectin levels and risk of type 2 diabetes: A systematic review and meta-analysis
-
Li S, Shin HJ, Ding EL, van Dam RM. Adiponectin levels and risk of type 2 diabetes: a systematic review and meta-analysis. JAMA, 302, 179-188 (2009).
-
(2009)
JAMA
, vol.302
, pp. 179-188
-
-
Li, S.1
Shin, H.J.2
Ding, E.L.3
Van Dam, R.M.4
-
34
-
-
0035852760
-
Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice
-
Fruebis J, Tsao TS, Javorschi S, Ebbets-Reed D, Erickson MR, Yen FT, Bihain BE, Lodish HF. Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc. Natl. Acad. Sci. U.S.A., 98, 2005-2010 (2001).
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 2005-2010
-
-
Fruebis, J.1
Tsao, T.S.2
Javorschi, S.3
Ebbets-Reed, D.4
Erickson, M.R.5
Yen, F.T.6
Bihain, B.E.7
Lodish, H.F.8
-
35
-
-
23044440661
-
Adipose-specific overexpression of GLUT4 reverses insulin resistance and diabetes in mice lacking GLUT4 selectively in muscle
-
Carvalho E, Kotani K, Peroni OD, Kahn BB. Adipose-specific overexpression of GLUT4 reverses insulin resistance and diabetes in mice lacking GLUT4 selectively in muscle. Am. J. Physiol. Endocrinol. Metab., 289, E551-E561 (2005).
-
(2005)
Am. J. Physiol. Endocrinol. Metab.
, vol.289
-
-
Carvalho, E.1
Kotani, K.2
Peroni, O.D.3
Kahn, B.B.4
-
36
-
-
0032409985
-
Thiazolidinediones and insulin resistance: Peroxisome proliferatoractivated receptor gamma activation stimulates expression of the CAP gene
-
Ribon V, Johnson JH, Camp HS, Saltiel AR. Thiazolidinediones and insulin resistance: peroxisome proliferatoractivated receptor gamma activation stimulates expression of the CAP gene. Proc. Natl. Acad. Sci. U.S.A., 95, 14751-14756 (1998).
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 14751-14756
-
-
Ribon, V.1
Johnson, J.H.2
Camp, H.S.3
Saltiel, A.R.4
-
37
-
-
10344236432
-
Regulated membrane trafficking of the insulin-responsive glucose transporter 4 in adipocytes
-
Watson RT, Kanzaki M, Pessin JE. Regulated membrane trafficking of the insulin-responsive glucose transporter 4 in adipocytes. Endocr. Rev., 25, 177-204 (2004).
-
(2004)
Endocr. Rev.
, vol.25
, pp. 177-204
-
-
Watson, R.T.1
Kanzaki, M.2
Pessin, J.E.3
|