Mechanism of thyrotoxic periodic paralysis

Journal of the American Society of Nephrology

Volumn 23, Issue 6, 2012, Pages 985-988

  Lin, Shih Hua ^a   Huang, Chou Long ^b  

^a TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADRENALIN; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIURETIC AGENT; GLUCOSE; INSULIN; MINERALOCORTICOID; SODIUM CHANNEL; THYROID HORMONE;

ADRENALIN BLOOD LEVEL; BARTTER SYNDROME; CHRONIC DISEASE; DEPOLARIZATION; GENETIC CODE; GITELMAN SYNDROME; HUMAN; HYPERINSULINEMIA; HYPERTHYROIDISM; HYPOKALEMIA; HYPOKALEMIC PERIODIC PARALYSIS; INSULIN BLOOD LEVEL; KIDNEY TUBULE ACIDOSIS; LOSS OF FUNCTION MUTATION; MEMBRANE STEADY POTENTIAL; MUSCLE STRENGTH; NEPHROLOGIST; NONHUMAN; PERIODIC PARALYSIS; POTASSIUM EXCRETION; POTASSIUM TRANSPORT; PRIORITY JOURNAL; SHORT SURVEY; SKELETAL MUSCLE; THYROTOXIC PERIODIC PARALYSIS;

EID: 84861835800     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2012010046     Document Type: Short Survey

References (16)

1. Aronson PS, Giebisch G: Effects of pH on potassium: New explanations for old observations. J AmSoc Nephrol 22: 1981-1989, 2011
2. Lin SH, Lin YF, Chen DT, Chu P, Hsu CW, Halperin ML: Laboratory tests to determine the cause of hypokalemia and paralysis. Arch Intern Med 164: 1561-1566, 2004 (Pubitemid 38970479)
3. Lin SH: Thyrotoxic periodic paralysis. Mayo Clin Proc 80: 99-105, 2005
4. Lin SH, Chu P, Cheng CJ, Chu SJ, Hung YJ, Lin YF: Early diagnosis of thyrotoxic periodic paralysis: Spot urine calcium to phosphate ratio. Crit Care Med 34: 2984-2989, 2006 (Pubitemid 44808742)
5. Shiang JC, Cheng CJ, Tsai MK, Hung YJ, Hsu YJ, Yang SS, Chu SJ, Lin SH: Therapeutic analysis in Chinese patients with thyrotoxic periodic paralysis over 6 years. Eur J Endocrinol 161: 911-916, 2009
6. Clausen T: Hormonal and pharmacological modification of plasma potassium homeostasis. FundamClin Pharmacol 24: 595-605, 2010
7. Chan A, Shinde R, Chow CC, Cockram CS, Swaminathan R: In vivo and in vitro sodium pump activity in subjects with thyrotoxic periodic paralysis. BMJ 303: 1096-1099, 1991
8. Lee KO, Taylor EA, Oh VM, Cheah JS, Aw SE: Hyperinsulinaemia in thyrotoxic hypokalaemic periodic paralysis. Lancet 337: 1063-1064, 1991
9. Maciel RM, Lindsey SC, Dias da Silva MR: Novel etiopathophysiological aspects of thyrotoxic periodic paralysis. Nat Rev Endocrinol 7: 657-667, 2011
10. Guerra M, Rodriguez del Castillo A, Battaner E, MasM: Androgens stimulate preoptic area Na+,K+-ATPase activity in male rats. Neurosci Lett 78: 97-100, 1987 (Pubitemid 17086566)
11. Kjeldsen K, EvertsME, Clausen T: The effects of thyroid hormones on 3H-ouabain binding site concentration, Na,K-contents and 86Rbefflux in rat skeletal muscle. Pflugers Arch 406: 529-435, 1986
12. Puwanant A, Ruff RL: INa and IKir are reduced in Type 1 hypokalemic and thyrotoxic periodic paralysis. Muscle Nerve 42: 315-327, 2010
13. Ruff RL: Insulin acts in hypokalemic periodic paralysis by reducing inward rectifier K+ current. Neurology 53: 1556-1563, 1999
14. Ryan DP, da Silva MR, Soong TW, Fontaine B, Donaldson MR, Kung AW, Jongjaroenprasert W, Liang MC, Khoo DH, Cheah JS, Ho SC, Bernstein HS, Maciel RM, Brown RH Jr, Ptácek LJ: Mutations in potassium channel Kir2.6 cause susceptibility to thyrotoxic hypokalemic periodic paralysis. Cell 140: 88-98, 2010
15. Cheng CJ, Lin SH, Lo YF, Yang SS, Hsu YJ, Cannon SC, Huang CL: Identification and functional characterization of Kir2.6 mutations associated with non-familial hypokalemic periodic paralysis. J Biol Chem 286: 27425-27435, 2011
16. Matthews E, Labrum R, Sweeney MG, Sud R, Haworth A, Chinnery PF, Meola G, Schorge S, Kullmann DM, Davis MB, Hanna MG: Voltage sensor charge loss accounts for most cases of hypokalemic periodic paralysis. Neurology 72: 1544-1547, 2009