Photochemical generation and reactivity of the major hydroxyl radical adduct of thymidine

Organic Letters

Volumn 14, Issue 11, 2012, Pages 2866-2869

  San Pedro, Joanna Maria N ^a   Greenberg, Marc M ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5,6 DIHYDRO 5 HYDROXYTHYMIDIN 6 YL RADICAL; 5,6-DIHYDRO-5-HYDROXYTHYMIDIN-6-YL RADICAL; DNA; DRUG DERIVATIVE; HYDROXYL RADICAL; THYMIDINE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; PHOTOCHEMISTRY;

DNA; HYDROXYL RADICAL; MOLECULAR STRUCTURE; PHOTOCHEMICAL PROCESSES; THYMIDINE;

EID: 84861819815     PISSN: 15237060     EISSN: 15237052     Source Type: Journal    
DOI: 10.1021/ol301109z     Document Type: Article

References (20)

1. von Sonntag, C. Free-Radical-Induced DNA Damage and Its Repair; Springer-Verlag: Berlin, 2006.
2. Pogozelski, W. K.; McNeese, T. J.; Tullius, T. D. J. Am. Chem. Soc. 1995, 117, 6428-33
3. Balasubramanian, B.; Pogozelski, W. K.; Tullius, T. D. Proc. Natl. Acad. Sci. U.S.A. 1998, 95, 9738-9743
4. Greenberg, M. M. Org. Biomol. Chem. 2007, 5, 18-30
5. Resendiz, M. J. E.; Pottiboyina, V.; Sevilla, M. D.; Greenberg, M. M. J. Am. Chem. Soc. 2012, 134, 3917-3924
6. Jacobs, A. C.; Resendiz, M. J. E.; Greenberg, M. M. J. Am. Chem. Soc. 2011, 133, 5152-5159
7. Giese, B.; Dussy, A.; Meggers, E.; Petretta, M.; Schwitter, U. J. Am. Chem. Soc. 1997, 119, 11130-11131
8. Hong, I. S.; Carter, K. N.; Sato, K.; Greenberg, M. M. J. Am. Chem. Soc. 2007, 129, 4089-4098
9. Carter, K. N.; Greenberg, M. M. J. Am. Chem. Soc. 2003, 125, 13376-13378
10. Greenberg, M. M.; Barvian, M. R.; Cook, G. P.; Goodman, B. K.; Matray, T. J.; Tronche, C.; Venkatesan, H. J. Am. Chem. Soc. 1997, 119, 1828-1839
11. Adam, W.; Arnold, M. A.; Nau, W. M.; Pischel, U.; Saha-Moeller, C. R. J. Am. Chem. Soc. 2002, 124, 3893-3904
12. Barvian, M. R.; Barkley, R. M.; Greenberg, M. M. J. Am. Chem. Soc. 1995, 117, 4894-4904
13. Zhang, Q.; Wang, Y. J. Am. Chem. Soc. 2004, 126, 13287-13297
14. Zhang, Q.; Wang, Y. Chem. Res. Toxicol. 2005, 18, 1897-1906
15. Gordon, D. M.; Danishefsky, S. J. Carbohydr. Res. 1990, 206, 361-366
16. Barvian, M. R.; Greenberg, M. M. J. Org. Chem. 1993, 58, 6151-4
17. Fleming, S. A.; Jensen, A. W. J. Org. Chem. 1996, 61, 7040-7044
18. Bonesi, S. M.; Fagnoni, M.; Dondi, D.; Albini, A. Inorg. Chim. Acta 2007, 360, 1230-1234
19. Newcomb, M. Tetrahedron 1993, 49, 1151-1176
20. Newman, C. A.; Resendiz, M. J. E.; Sczepanski, J. T.; Greenberg, M. M. J. Org. Chem. 2009, 74, 7007-7012