Neonatal administration with dexmedetomidine does not impair the rat hippocampal synaptic plasticity later in adulthood

Paediatric Anaesthesia

Volumn 22, Issue 7, 2012, Pages 713-719

  Tachibana, Kaori ^a   Hashimoto, Toshikazu ^a   Kato, Rui ^a   Uchida, Yosuke ^a   Ito, Ryoko ^a   Takita, Koichi ^a   Morimoto, Yuji ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

development; dexmedetomidine; hippocampus; long term potentiation; synaptic plasticity

Indexed keywords

DEXMEDETOMIDINE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG DOSE COMPARISON; EVOKED RESPONSE; HIPPOCAMPUS; IN VIVO STUDY; LONG TERM POTENTIATION; MALE; NERVE CELL PLASTICITY; NONHUMAN; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; RAT; RESPIRATION DEPRESSION; SEDATION;

ADRENERGIC ALPHA-AGONISTS; ANIMALS; ANIMALS, NEWBORN; BLOOD GAS ANALYSIS; CA1 REGION, HIPPOCAMPAL; DEXMEDETOMIDINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHYSIOLOGICAL PROCESSES; EVOKED POTENTIALS; HIPPOCAMPUS; LONG-TERM POTENTIATION; MALE; MEMBRANE POTENTIALS; NEURONAL PLASTICITY; PYRAMIDAL CELLS; RATS; RATS, WISTAR; SYNAPSES; SYNAPTIC TRANSMISSION;

EID: 84861815919     PISSN: 11555645     EISSN: 14609592     Source Type: Journal    
DOI: 10.1111/j.1460-9592.2012.03810.x     Document Type: Article

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