Inulin-Based Hydrogel for Oral Delivery of Flutamide: Preparation, Characterization, and in vivo Release Studies

Macromolecular Bioscience

Volumn 12, Issue 6, 2012, Pages 770-778

  Pitarresi, Giovanna ^a,b   Triolo, Daniela ^a   Giorgi, Mario ^c   Fiorica, Calogero ^a   Calascibetta, Filippo ^a   Giammona, Gaetano ^a,d  

^a UNIVERSITY OF PALERMO   (Italy)

^b CNR Consiglio Nazionale delle Ricerche   (Italy)

^c UNIVERSITY OF PISA   (Italy)

^d CNR   (Italy)

Author keywords

Drug delivery systems; Flutamide; Hydrogels; In vivo release; Inulin

Indexed keywords

ACTIVE METABOLITES; DRUG DELIVERY SYSTEM; DRUG LOADING; FLUTAMIDE; IN-VITRO; IN-VIVO; INULIN; MICRO-PARTICLES; MUCOADHESIVE PROPERTIES; ORAL DELIVERY; POST-FABRICATION; SUSTAINED RELEASE; TOXIC SOLVENTS;

BIOCHEMISTRY; DRUG DELIVERY; LOADING; POLYSACCHARIDES;

HYDROGELS;

FLUTAMIDE; INULIN;

ANIMAL EXPERIMENT; ARTICLE; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG HALF LIFE; DRUG MARKETING; DRUG RELEASE; DRUG SYNTHESIS; ENCAPSULATION; HYDROGEL; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; PH; TABLET;

ADMINISTRATION, ORAL; ANDROGEN ANTAGONISTS; ANIMALS; BIOLOGICAL AVAILABILITY; DOGS; DRUG DELIVERY SYSTEMS; FLUTAMIDE; HALF-LIFE; HYDROGELS; HYPOGLYCEMIC AGENTS; INSULIN; MALE;

CANIS FAMILIARIS;

EID: 84861778538     PISSN: 16165187     EISSN: 16165195     Source Type: Journal    
DOI: 10.1002/mabi.201200003     Document Type: Article

References (25)

1. W. N. Charman, H. K. Chan, B. C. Finnin, S. A. Charman, Drug Dev. Res. 1999, 46, 316.
2. L. Y. Qiu, Y. H. Bae, Pharm. Res. 2006, 23, 1.
3. S. Amin, S. Rajabnezhad, K. Kohli, Sci. Res. Essay 2009, 3, 1175.
4. L. Yu, J. Ding, Chem. Soc. Rev. 2008, 37, 1473.
5. G. Tripodo, G. Pitarresi, F. S. Palumbo, E. F. Craparo, G. Giammona, Macromol. Biosci. 2005, 5, 1074.
6. N. Bhattarai, J. Gunn, M. Zhang, Adv. Drug Delivery Rev. 2010, 62, 83.
7. R. Muzzalupo, F. Iemma, N. Picci, G. Pitarresi, G. Cavallaro, G. Giammona, Colloid Polym. Sci. 2001, 279, 688.
8. D. Mandracchia, G. Pitarresi, F. S. Palumbo, B. Carlisi, G. Giammona, Biomacromolecules 2004, 5, 1973.
9. G. Pitarresi, P. Pierro, F. S. Palumbo, G. Tripodo, G. Giammona, Biomacromolecules 2006, 7, 1302.
10. G. Pitarresi, F. S. Palumbo, G. Giammona, M. A. Casadei, F. Micheletti Moracci, Biomaterials 2033, 24, 4301.
11. J. Van Loo, P. Coussement, L. De Leenheer, H. Hoebregs, G. Smit, Crit. Rev. Food Sci. Nutr. 1995, 36, 525.
12. S. Kolida, G. R. Gibson, J. Nutr. 2007, 137, 2503S.
13. L. Vervoort, G. Van den Mooter, P. Augustijns, R. Busson, S. Toppet, R. Kinget, Pharm. Res. 1997, 14, 1730.
14. G. Pitarresi, G. Tripodo, G. Cavallaro, F. S. Palumbo, G. Giammona, Eur. J. Pharm. Biopharm. 2008, 68, 267.
15. C. V. Stevens, A. Meriggi, K. Booten, Biomacromolecules 2001, 2, 1.
16. D. C. Meadows, J. Gervay-Hague, Med. Res. Rev. 2006, 26, 793.
17. C. Hiemstra, L. J. Van Der Aa, Z. Zhong, P. J. Dijkstra, J. Feijen, Macromolecules 2007, 40, 1165.
18. G. Pitarresi, G. Tripodo, D. Triolo, C. Fiorica, G. Giammona, J. Drug Delivery Sci. Technol. 2009, 19, 419.
19. Y. Bin Choy, J. H. Park, M. R. Prausnitz, J. Phys. Chem. Solids 2008, 69, 1533.
20. Z. Zu, K. Tam Yun, J. Diakur, L. I. Wiebe, J. Pharm. Pharm. Sci. 2002, 5, 292.
21. J. Gabrielsson, D. Weiner, Pharmacokinetic and Pharmacodynamic Data Analysis: Concepts and Applications, Swedish Pharmaceutical Press, Stockholm 2002.
22. W. P. Wuelfing, K. Kosuda, A. C. Templeton, A. Harman, M. D. Mowery, R. A. Reed, J. Pharm. Biomed. Anal. 2006, 41, 774.
23. G. W. Sinclair, N. A. Peppas, J. Membr. Sci. 1984, 17, 329.
24. P. L. Ritger, N. A. Peppas, J. Controlled Release 1987, 5, 37.
25. N. A. Peppas, J. J. Sahlin, Int. J. Pharm. 1989, 57, 169.