메뉴 건너뛰기




Volumn 18, Issue 11, 2012, Pages 3132-3141

Mutations in the Ras-Raf axis underlie the prognostic value of CD133 in colorectal cancer

Author keywords

[No Author keywords available]

Indexed keywords

CD133 ANTIGEN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE; RAF PROTEIN; RAS PROTEIN; TUMOR MARKER;

EID: 84861767268     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-11-3066     Document Type: Article
Times cited : (78)

References (52)
  • 1
    • 77957948992 scopus 로고    scopus 로고
    • Molecular predictive and prognostic markers in colon cancer
    • Winder T, Lenz HJ. Molecular predictive and prognostic markers in colon cancer. Cancer Treat Rev 2010;36:550-6.
    • (2010) Cancer Treat Rev , vol.36 , pp. 550-556
    • Winder, T.1    Lenz, H.J.2
  • 2
    • 75449109041 scopus 로고    scopus 로고
    • Tumour CD133 mRNA expression and clinical outcome in surgically resected colorectal cancer patients
    • Artells R, Moreno I, Diaz T, Martinez F, Gel B, Navarro A, et al. Tumour CD133 mRNA expression and clinical outcome in surgically resected colorectal cancer patients. Eur J Cancer 2010;46:642-9.
    • (2010) Eur J Cancer , vol.46 , pp. 642-649
    • Artells, R.1    Moreno, I.2    Diaz, T.3    Martinez, F.4    Gel, B.5    Navarro, A.6
  • 3
    • 78649669323 scopus 로고    scopus 로고
    • CD133 mRNA expression and microsatellite instability in colorectal carcinoma
    • Huh JW, Park YS, Lee JH, Kim HR, Shin MG, Kim YJ. CD133 mRNA expression and microsatellite instability in colorectal carcinoma. J Surg Oncol 2010;102:765-70.
    • (2010) J Surg Oncol , vol.102 , pp. 765-770
    • Huh, J.W.1    Park, Y.S.2    Lee, J.H.3    Kim, H.R.4    Shin, M.G.5    Kim, Y.J.6
  • 4
    • 77649272778 scopus 로고    scopus 로고
    • CD133 expression predicts for non-response to chemotherapy in colorectal cancer
    • Ong CW, Kim LG, Kong HH, Low LY, Iacopetta B, Soong R, et al. CD133 expression predicts for non-response to chemotherapy in colorectal cancer. Mo Pathol 2010;23:450-7.
    • (2010) Mo Pathol , vol.23 , pp. 450-457
    • Ong, C.W.1    Kim, L.G.2    Kong, H.H.3    Low, L.Y.4    Iacopetta, B.5    Soong, R.6
  • 5
    • 68349114796 scopus 로고    scopus 로고
    • Higher percentage of CD133(+) cells is associated with poor prognosis in colon carcinoma patients with stage IIIB
    • Li CY, Li BX, Liang Y, Peng RQ, Ding Y, Xu DZ, et al. Higher percentage of CD133(+) cells is associated with poor prognosis in colon carcinoma patients with stage IIIB. J Trans Med 2009;7:56.
    • (2009) J Trans Med , vol.7 , pp. 56
    • Li, C.Y.1    Li, B.X.2    Liang, Y.3    Peng, R.Q.4    Ding, Y.5    Xu, D.Z.6
  • 6
    • 71549155909 scopus 로고    scopus 로고
    • Correlation of CD133, OCT4, and SOX2 in rectal cancer and their association with distant recurrence after chemoradiotherapy
    • Saigusa S, Tanaka K, Toiyama Y, Yokoe T, Okugawa Y, Ioue Y, et al. Correlation of CD133, OCT4, and SOX2 in rectal cancer and their association with distant recurrence after chemoradiotherapy. Ann Surg Oncol 2009;16:3488-98.
    • (2009) Ann Surg Oncol , vol.16 , pp. 3488-3498
    • Saigusa, S.1    Tanaka, K.2    Toiyama, Y.3    Yokoe, T.4    Okugawa, Y.5    Ioue, Y.6
  • 7
    • 77954350454 scopus 로고    scopus 로고
    • Immunohistochemical features ofCD133 expression: Association with resistance to chemoradiotherapy in rectal cancer
    • Saigusa S, Tanaka K, Toiyama Y, Yokoe T, Okugawa Y, Kawamoto A, et al. Immunohistochemical features ofCD133 expression: association with resistance to chemoradiotherapy in rectal cancer. Oncol Rep 2010;24:345-50.
    • (2010) Oncol Rep , vol.24 , pp. 345-350
    • Saigusa, S.1    Tanaka, K.2    Toiyama, Y.3    Yokoe, T.4    Okugawa, Y.5    Kawamoto, A.6
  • 8
    • 8444241199 scopus 로고    scopus 로고
    • ALCAM/CD166 is overexpressed in colorectal carcinoma and correlates with shortened patient survival
    • DOI 10.1136/jcp.2004.016238
    • Weichert W, Knosel T, Bellach J, Dietel M, Kristiansen G. ALCAM/ CD166 is overexpressed in colorectal carcinoma and correlates with shortened patient survival. J Clin Pathol 2004;57:1160-4. (Pubitemid 39486521)
    • (2004) Journal of Clinical Pathology , vol.57 , Issue.11 , pp. 1160-1164
    • Weichert, W.1    Knosel, T.2    Bellach, J.3    Dietel, M.4    Kristiansen, G.5
  • 12
    • 78149310691 scopus 로고    scopus 로고
    • Frequency and pattern of expression of the stem cell marker CD133 have strong prognostic effect on the surgical outcome of colorectal cancer patients
    • Takahashi S, Kamiyama T, Tomaru U, Ishizu A, Shida T, Osaka M, et al. Frequency and pattern of expression of the stem cell marker CD133 have strong prognostic effect on the surgical outcome of colorectal cancer patients. Oncol Rep 2010;24:1201-12.
    • (2010) Oncol Rep , vol.24 , pp. 1201-1212
    • Takahashi, S.1    Kamiyama, T.2    Tomaru, U.3    Ishizu, A.4    Shida, T.5    Osaka, M.6
  • 13
    • 72249120793 scopus 로고    scopus 로고
    • The cancer stem cell marker CD133 has high prognostic impact but unknown functional relevance for the metastasis of human colon cancer
    • Horst D, Scheel SK, Liebmann S, Neumann J, Maatz S, Kirchner T, et al. The cancer stem cell marker CD133 has high prognostic impact but unknown functional relevance for the metastasis of human colon cancer. J Pathol 2009;219:427-34.
    • (2009) J Pathol , vol.219 , pp. 427-434
    • Horst, D.1    Scheel, S.K.2    Liebmann, S.3    Neumann, J.4    Maatz, S.5    Kirchner, T.6
  • 14
    • 70249130832 scopus 로고    scopus 로고
    • Prognostic significance of the cancer stem cell markers CD133, CD44, and CD166 in colorectal cancer
    • Horst D, Kriegl L, Engel J, Kirchner T, Jung A. Prognostic significance of the cancer stem cell markers CD133, CD44, and CD166 in colorectal cancer. Cancer Invest 2009;27:844-50.
    • (2009) Cancer Invest , vol.27 , pp. 844-850
    • Horst, D.1    Kriegl, L.2    Engel, J.3    Kirchner, T.4    Jung, A.5
  • 17
    • 60549106250 scopus 로고    scopus 로고
    • Characterization of a subpopulation of colon cancer cells with stem cell-like properties
    • Chu P, Clanton DJ, Snipas TS, Lee J, Mitchell E, Nguyen ML, et al. Characterization of a subpopulation of colon cancer cells with stem cell-like properties. Int J Cancer 2009;124:1312-21.
    • (2009) Int J Cancer , vol.124 , pp. 1312-1321
    • Chu, P.1    Clanton, D.J.2    Snipas, T.S.3    Lee, J.4    Mitchell, E.5    Nguyen, M.L.6
  • 19
  • 20
    • 33846100356 scopus 로고    scopus 로고
    • A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
    • DOI 10.1038/nature05372, PII NATURE05372
    • O'Brien CA, Pollett A, Gallinger S, Dick JE. A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 2007;445:106-10. (Pubitemid 46067310)
    • (2007) Nature , vol.445 , Issue.7123 , pp. 106-110
    • O'Brien, C.A.1    Pollett, A.2    Gallinger, S.3    Dick, J.E.4
  • 21
  • 24
    • 65949112714 scopus 로고    scopus 로고
    • Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis
    • Huang EH, Hynes MJ, Zhang T, Ginestier C, Dontu G, Appelman H, et al. Aldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis. Cancer Res 2009;69:3382-9.
    • (2009) Cancer Res , vol.69 , pp. 3382-3389
    • Huang, E.H.1    Hynes, M.J.2    Zhang, T.3    Ginestier, C.4    Dontu, G.5    Appelman, H.6
  • 27
    • 76549120193 scopus 로고    scopus 로고
    • The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation
    • Kemper K, Sprick MR, de Bree M, Scopelliti A, Vermeulen L, Hoek M, et al. The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation. Cancer Res 2010;70:719-29.
    • (2010) Cancer Res , vol.70 , pp. 719-729
    • Kemper, K.1    Sprick, M.R.2    De Bree, M.3    Scopelliti, A.4    Vermeulen, L.5    Hoek, M.6
  • 28
    • 81755172443 scopus 로고    scopus 로고
    • CD133 protein N-glycosylation processing contributes to cell surface recognition of the primitive cell marker AC133 epitope
    • Mak AB, Blakely KM, Williams RA, Penttila PA, Shukalyuk AI, Osman KT, et al. CD133 protein N-glycosylation processing contributes to cell surface recognition of the primitive cell marker AC133 epitope. J Biol Chem 2011;286:41046-56.
    • (2011) J Biol Chem , vol.286 , pp. 41046-41056
    • Mak, A.B.1    Blakely, K.M.2    Williams, R.A.3    Penttila, P.A.4    Shukalyuk, A.I.5    Osman, K.T.6
  • 29
    • 0028879677 scopus 로고
    • P53 point mutation and survival in colorectal- Cancer patients
    • Goh HS, Yao J, Smith DR. P53 point mutation and survival in colorectal- cancer patients. Cancer Res 1995;55:5217-21.
    • (1995) Cancer Res , vol.55 , pp. 5217-5221
    • Goh, H.S.1    Yao, J.2    Smith, D.R.3
  • 34
    • 75749102647 scopus 로고    scopus 로고
    • Prognostic role of KRAS and BRAF in stage II and III resected colon cancer: Results of the translational study on the PETACC-3, EORTC 40993, SAKK 60-00 trial
    • Roth AD, Tejpar S, Delorenzi M, Yan P, Fiocca R, Klingbiel D, et al. Prognostic role of KRAS and BRAF in stage II and III resected colon cancer: results of the translational study on the PETACC-3, EORTC 40993, SAKK 60-00 trial. J Clin Oncol 2010;28:466-74.
    • (2010) J Clin Oncol , vol.28 , pp. 466-474
    • Roth, A.D.1    Tejpar, S.2    Delorenzi, M.3    Yan, P.4    Fiocca, R.5    Klingbiel, D.6
  • 35
    • 33947594129 scopus 로고    scopus 로고
    • Hyperactive Ras in developmental disorders and cancer
    • DOI 10.1038/nrc2109, PII NRC2109
    • Schubbert S, Shannon K, Bollag G. Hyperactive Ras in developmental disorders and cancer. Nat Rev Cancer 2007;7:295-308. (Pubitemid 46480970)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.4 , pp. 295-308
    • Schubbert, S.1    Shannon, K.2    Bollag, G.3
  • 37
    • 1342299898 scopus 로고    scopus 로고
    • Mutation analysis of the BRAF, ARAF and RAF-1 genes in human colorectal adenocarcinomas
    • DOI 10.1093/carcin/bgh049
    • Fransen K, Klintenas M, Osterstrom A, Dimberg J, Monstein HJ, Soderkvist P. Mutation analysis of the BRAF, ARAF and RAF-1 genes in human colorectal adenocarcinomas. Carcinogenesis 2004;25: 527-33. (Pubitemid 38528645)
    • (2004) Carcinogenesis , vol.25 , Issue.4 , pp. 527-533
    • Fransen, K.1    Klintenas, M.2    Osterstrom, A.3    Dimberg, J.4    Monstein, H.-J.5    Soderkvist, P.6
  • 38
    • 80755141289 scopus 로고    scopus 로고
    • Methylation of cancer-stem-cell-associated Wnt target genes predicts poor prognosis in colorectal cancer patients
    • Melo FDE, Colak S, Buikhuisen J, Koster J, Cameron K, de Jong JH, et al. Methylation of cancer-stem-cell-associated Wnt target genes predicts poor prognosis in colorectal cancer patients. Cell Stem Cell 2011;9:476-85.
    • (2011) Cell Stem Cell , vol.9 , pp. 476-485
    • Melo, F.D.E.1    Colak, S.2    Buikhuisen, J.3    Koster, J.4    Cameron, K.5    De Jong, J.H.6
  • 40
    • 77949905958 scopus 로고    scopus 로고
    • The polyamine metabolism genes ornithine decarboxylase and antizyme 2 predict aggressive behavior in neuroblastomas with and without MYCN amplification
    • Geerts D, Koster J, Albert D, Koomoa DLT, Feith DJ, Pegg AE, et al. The polyamine metabolism genes ornithine decarboxylase and antizyme 2 predict aggressive behavior in neuroblastomas with and without MYCN amplification. Int J Cancer 2010;126:2012-24.
    • (2010) Int J Cancer , vol.126 , pp. 2012-2024
    • Geerts, D.1    Koster, J.2    Albert, D.3    Koomoa, D.L.T.4    Feith, D.J.5    Pegg, A.E.6
  • 41
    • 33645772227 scopus 로고    scopus 로고
    • Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain
    • Sun LX, Hui AM, Su Q, Vortmeyer A, Kotliarov Y, Pastorino S, et al. Neuronal and glioma-derived stem cell factor induces angiogenesis within the brain. Cancer Cell 2006;9:287-300.
    • (2006) Cancer Cell , vol.9 , pp. 287-300
    • Sun, L.X.1    Hui, A.M.2    Su, Q.3    Vortmeyer, A.4    Kotliarov, Y.5    Pastorino, S.6
  • 43
    • 56449104265 scopus 로고    scopus 로고
    • Mutation of ERBB2 provides a novel alternative mechanism for the ubiquitous activation of RAS-MAPK in ovarian serous low malignant potential tumors
    • Anglesio MS, Arnold JM, George J, Tinker AV, Tothill R, Waddell N, et al. Mutation of ERBB2 provides a novel alternative mechanism for the ubiquitous activation of RAS-MAPK in ovarian serous low malignant potential tumors. Mol Cancer Res 2008;6:1678-90.
    • (2008) Mol Cancer Res , vol.6 , pp. 1678-1690
    • Anglesio, M.S.1    Arnold, J.M.2    George, J.3    Tinker, A.V.4    Tothill, R.5    Waddell, N.6
  • 44
    • 0027905014 scopus 로고
    • Altered growth of human colon cancer cell lines disrupted at activated Ki-ras
    • Shirasawa S, Furuse M, Yokoyama N, Sasazuki T. Altered growth of human colon cancer cell-lines disrupted at activated Ki-Ras. Science 1993;260:85-8. (Pubitemid 23122749)
    • (1993) Science , vol.259 , Issue.5104 , pp. 85-88
    • Shirasawa, S.1    Furuse, M.2    Yokoyama, N.3    Sasazuki, T.4
  • 45
    • 53349167537 scopus 로고    scopus 로고
    • Promoter hypomethylation regulates CD133 expression in human gliomas
    • Tabu K, Sasai K, Kimura T, Wang L, Aoyanagi E, Kohsaka S, et al. Promoter hypomethylation regulates CD133 expression in human gliomas. Cell Res 2008;18:1037-46.
    • (2008) Cell Res , vol.18 , pp. 1037-1046
    • Tabu, K.1    Sasai, K.2    Kimura, T.3    Wang, L.4    Aoyanagi, E.5    Kohsaka, S.6
  • 46
    • 54249127417 scopus 로고    scopus 로고
    • Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors
    • Yi JM, Tsai HC, Glockner SC, Lin S, Ohm JE, Easwaran H, et al. Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors. Cancer Res 2008;68:8094-103.
    • (2008) Cancer Res , vol.68 , pp. 8094-8103
    • Yi, J.M.1    Tsai, H.C.2    Glockner, S.C.3    Lin, S.4    Ohm, J.E.5    Easwaran, H.6
  • 47
    • 77649307110 scopus 로고    scopus 로고
    • Analysis of an alternative human CD133 promoter reveals the implication of Ras/ERK pathway in tumor stem-like hallmarks
    • Tabu K, Kimura T, Sasai K, Wang L, Bizen N, Nishihara H, et al. Analysis of an alternative human CD133 promoter reveals the implication of Ras/ERK pathway in tumor stem-like hallmarks. Mol Cancer 2010; 9:39.
    • (2010) Mol Cancer , vol.9 , pp. 39
    • Tabu, K.1    Kimura, T.2    Sasai, K.3    Wang, L.4    Bizen, N.5    Nishihara, H.6
  • 48
    • 63149111430 scopus 로고    scopus 로고
    • Ras/Raf-1/MAPK pathway mediates response to tamoxifen but not chemotherapy in breast cancer patients
    • McGlynn LM, Kirkegaard T, Edwards J, Tovey S, Cameron D, Twelves C, et al. Ras/Raf-1/MAPK pathway mediates response to tamoxifen but not chemotherapy in breast cancer patients. Clin Cancer Res 2009;15:1487-95.
    • (2009) Clin Cancer Res , vol.15 , pp. 1487-1495
    • McGlynn, L.M.1    Kirkegaard, T.2    Edwards, J.3    Tovey, S.4    Cameron, D.5    Twelves, C.6
  • 49
    • 77953916705 scopus 로고    scopus 로고
    • K-ras mutational status predicts poor prognosis in unresectable pancreatic cancer
    • Chen H, Tu H, Meng ZQ, Chen Z, Wang P, Liu LM. K-ras mutational status predicts poor prognosis in unresectable pancreatic cancer. Eur J Surg Oncol 2010;36:657-62.
    • (2010) Eur J Surg Oncol , vol.36 , pp. 657-662
    • Chen, H.1    Tu, H.2    Meng, Z.Q.3    Chen, Z.4    Wang, P.5    Liu, L.M.6
  • 50
    • 79956051553 scopus 로고    scopus 로고
    • Expression and prognostic role of pan-Ras, Raf-1, pMEK1 and pERK1/2 in patients with hepatocellular carcinoma
    • Chen L, Shi Y, Jiang CY, Wei LX, Wang YL, Dai GH. Expression and prognostic role of pan-Ras, Raf-1, pMEK1 and pERK1/2 in patients with hepatocellular carcinoma. Eur J Surg Oncol 2011;37:513-20.
    • (2011) Eur J Surg Oncol , vol.37 , pp. 513-520
    • Chen, L.1    Shi, Y.2    Jiang, C.Y.3    Wei, L.X.4    Wang, Y.L.5    Dai, G.H.6
  • 51
    • 79951491860 scopus 로고    scopus 로고
    • Genetic alterations in the K-Ras gene influence the prognosis in patients with cervical cancer treated by radiotherapy
    • Wegman P, Ahlin C, Sorbe B. Genetic alterations in the K-Ras gene influence the prognosis in patients with cervical cancer treated by radiotherapy. Int J Gynecol Cancer 2011;21:86-91.
    • (2011) Int J Gynecol Cancer , vol.21 , pp. 86-91
    • Wegman, P.1    Ahlin, C.2    Sorbe, B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.