A novel method for determination of drug distribution in rat brain tissue sections by LC/MS/MS: Functional tissue microanalysis

Current Topics in Medicinal Chemistry

Volumn 12, Issue 11, 2012, Pages 1243-1249

  Masucci, John A ^a   Mahan, Andrew D ^a   Kwasnoski, Joseph D ^a   Caldwell, Gary W ^a  

^a JANSSEN RESEARCH AND DEVELOPMENT   (United States)

Author keywords

Electrospray; FTM; Functional tissue microanalysis; LC MS; MALDI; Mass spectral imaging; Matrix assisted laser desorption ionization

Indexed keywords

RACLOPRIDE; RIMONABANT; VERAPAMIL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN TISSUE; CONTROLLED STUDY; DISSECTION; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG LIVER LEVEL; ELECTROSPRAY; FUNCTIONAL TISSUE MICROANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETER; MASS SPECTROMETRY; MEASUREMENT; MICROANALYSIS; MICROARRAY ANALYSIS; NONHUMAN; QUANTITATIVE ANALYSIS; RAT; REPRODUCIBILITY;

EID: 84861758257     PISSN: 15680266     EISSN: 18734294     Source Type: Journal    
DOI: 10.2174/156802612800672916     Document Type: Article

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