Editorial

Translational Stroke Research

Volumn 3, Issue 2, 2012, Pages 173-177

  Lin, Weili ^a   Powers, William J ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CONTRAST MEDIUM; OXYGEN; OXYGEN 15; SODIUM ION; TISSUE PLASMINOGEN ACTIVATOR;

BRAIN HEMORRHAGE; BRAIN ISCHEMIA; CEREBRAL METABOLIC RATE OF OXYGEN; CLINICAL TRIAL (TOPIC); COMPUTER ASSISTED TOMOGRAPHY; DIFFUSION WEIGHTED IMAGING; DRUG EFFICACY; EDITORIAL; EXPERIMENTAL ANIMAL; EXPERIMENTAL MODEL; HEMODYNAMICS; HUMAN; IMAGING SYSTEM; NEUROIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PHASE 3 CLINICAL TRIAL (TOPIC); POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; STANDARDIZATION; STROKE; STROKE PATIENT;

EID: 84861716817     PISSN: 18684483     EISSN: 1868601X     Source Type: Journal    
DOI: 10.1007/s12975-012-0173-x     Document Type: Editorial

References (45)

1. Powers WJ, et al. Cerebral blood flow and cerebral metabolic rate of oxygen requirements for cerebral function and viability in humans. J Cereb Blood Flow Metab. 1985; 5(4): 600-8.
2. Baron JC, et al. Noninvasive tomographic study of cerebral blood flow and oxygen metabolism in vivo. Potentials, limitations, and clinical applications in cerebral ischemic disorders. Eur Neurol. 1981; 20(3): 273-84.
3. Wise RJ, et al. Serial observations on the pathophysiology of acute stroke. The transition from ischaemia to infarction as reflected in regional oxygen extraction. Brain. 1983; 106(Pt 1): 197-222.
4. Moseley ME, et al. Diffusion-weighted MR imaging of acute stroke: correlation with T2-weighted and magnetic susceptibility-enhanced MR imaging in cats. AJNR Am J Neuroradiol. 1990; 11(3): 423-9.
5. Rosen BR, et al. MR depicts perfusion of brain and heart. Diagn Imaging (San Franc). 1991; 13(11): 105-10.
6. No authors listed. Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. N Engl J Med. 1995; 333(24): 1581-7.
7. Hacke W, et al. Thrombolysis with alteplase 3 to 4. 5 hours after acute ischemic stroke. N Engl J Med. 2008; 359(13): 1317-29.
8. Lees KR, et al. Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials. Lancet. 2010; 375(9727): 1695-703.
9. Paciaroni M, Caso V, Agnelli G. The concept of ischemic penumbra in acute stroke and therapeutic opportunities. Eur Neurol. 2009; 61(6): 321-30.
10. Heiss WD. The ischemic penumbra: correlates in imaging and implications for treatment of ischemic stroke. The Johann Jacob Wepfer award 2011. Cerebrovasc Dis. 2011; 32(4): 307-20.
11. Smith WS, et al. Mechanical thrombectomy for acute ischemic stroke: final results of the Multi MERCI trial. Stroke. 2008; 39(4): 1205-12.
12. Penumbra Pivotal Stroke Trial Investigators. The penumbra pivotal stroke trial: safety and effectiveness of a new generation of mechanical devices for clot removal in intracranial large vessel occlusive disease. Stroke. 2009; 40(8): 2761-8.
13. Costalat V, et al. Rescue, combined, and stand-alone thrombectomy in the management of large vessel occlusion stroke using the solitaire device: a prospective 50-patient single-center study: timing, safety, and efficacy. Stroke. 2011; 42(7): 1929-35.
14. Rohl L, et al. Viability thresholds of ischemic penumbra of hyperacute stroke defined by perfusion-weighted MRI and apparent diffusion coefficient. Stroke. 2001; 32(5): 1140-6.
15. Neumann-Haefelin T, et al. Diffusion- and perfusion-weighted MRI. The DWI/PWI mismatch region in acute stroke. Stroke. 1999; 30(8): 1591-7.
16. Schwamm LH, et al. Time course of lesion development in patients with acute stroke: serial diffusion- and hemodynamic-weighted magnetic resonance imaging. Stroke. 1998; 29(11): 2268-76.
17. Kidwell CS, et al. Thrombolytic reversal of acute human cerebral ischemic injury shown by diffusion/perfusion magnetic resonance imaging. Ann Neurol. 2000; 47(4): 462-9.
18. Fiehler J, et al. Severe ADC decreases do not predict irreversible tissue damage in humans. Stroke. 2002; 33(1): 79-86.
19. Davis S, et al. Perfusion/diffusion mismatch is valid and should be used for selecting delayed interventions. TSR, 2012.
20. Chemmanam T, et al. Ischemic diffusion lesion reversal is uncommon and rarely alters perfusion-diffusion mismatch. Neurology. 2010; 75(12): 1040-7.
21. Campbell BC, et al. The infarct core is well represented by the acute diffusion lesion: sustained reversal is infrequent. J Cereb Blood Flow Metab. 2012; 32(1): 50-6.
22. Davis SM, et al. Effects of alteplase beyond 3h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial. Lancet Neurol. 2008; 7(4): 299-309.
23. Barber PA, et al. Prediction of stroke outcome with echoplanar perfusion- and diffusion-weighted MRI. Neurology. 1998; 51(2): 418-26.
24. Powers WJ. Perfusion-diffusion mismatch: does it identify who will benefit from reperfusion therapy? TSR, 2012.
25. Albers GW, et al. Magnetic resonance imaging profiles predict clinical response to early reperfusion: the diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) study. Ann Neurol. 2006; 60(5): 508-17.
26. Albers G. Results of DEFUSE-2: Imaging endpoints. International Stoke Conference, 2012.
27. Lansberg MG. Results of DEFUSE-2: clinical endpoints. International Stoke Conference, 2012.
28. Zhu GM, et al. Standardization of stroke perfusion CT for reperfusion therapy. TSR, 2012.
29. Dani KA, et al. Computed tomography and magnetic resonance perfusion imaging in ischemic stroke: definitions and thresholds. Ann Neurol. 2011; 70(3): 384-401.
30. Harkins KD, et al. Assessment of the effects of cellular tissue properties on ADC measurements by numerical simulation of water diffusion. Magn Reson Med. 2009; 62(6): 1414-22.
31. Gass A, Niendorf T, Hirsch JG. Acute and chronic changes of the apparent diffusion coefficient in neurological disorders-biophysical mechanisms and possible underlying histopathology. J Neurol Sci. 2001; 186 Suppl 1: S15-23.
32. d'Esterre CD, et al. Improving acute stroke management with computed tomography perfusion: a review of imaging basics and applications. TSR, 2012.
33. Ford AL, et al. Defining the ischemic penumbra using hyperacute neuroimaging: deriving quantitative ischemic thresholds. TSR, 2012.
34. Baron JC. Mapping the ischaemic penumbra with PET: a new approach. Brain. 2001; 124(Pt 1): 2-4.
35. Touzani O, et al. Progressive impairment of brain oxidative metabolism reversed by reperfusion following middle cerebral artery occlusion in anaesthetized baboons. Brain Res. 1997; 767(1): 17-25.
36. An H, Lin W. Quantitative measurements of cerebral blood oxygen saturation using magnetic resonance imaging. J Cereb Blood Flow Metab. 2000; 20(8): 1225-36.
37. An H, et al. Quantitative measurements of cerebral metabolic rate of oxygen utilization using MRI: a volunteer study. NMR Biomed. 2001; 14(7-8): 441-7.
38. An H, et al. Evaluation of MR-derived cerebral oxygen metabolic index in experimental hyperoxic hypercapnia, hypoxia, and ischemia. Stroke. 2009; 40(6): 2165-72.
39. Lee JM, et al. Magnetic resonance cerebral metabolic rate of oxygen utilization in hyperacute stroke patients. Ann Neurol. 2003; 53(2): 227-32.
40. An H, et al. Quantification of cerebral blood flow, oxygen extraction fraction and oxygen metabolic index in human with inhalation of air and carbogen. TSR, 2012.
41. Zaharchuk G. Arterial spin labeling for acute stroke: practical considerations. TSR, 2012.
42. Boada FE, et al. Sodium MRI and assessment of irreversible tissue damage during hyperacute stroke. TSR, 2012.
43. LaVerde G, et al. Serial triple quantum sodium MRI during non-human primate focal brain ischemia. Magn Reson Med. 2007; 57(1): 201-5.
44. Jones SC, et al. Stroke onset time using sodium MRI in rat focal cerebral ischemia. Stroke. 2006; 37(3): 883-8.
45. Boada FE, et al. Loss of cell ion homeostasis and cell viability in the brain: what sodium MRI can tell us. Curr Top Dev Biol. 2005; 70: 77-101.