Bone metabolism in patients with primary hyperparathyroidism before and after surgery

Hormone and Metabolic Research

Volumn 44, Issue 6, 2012, Pages 476-481

  Kerschan Schindl, K ^a   Riss, P ^a   Krestan, C ^a   Rauner, M ^b,c   Bieglmayer, C ^a   Gleiss, A ^a   Fialka Moser, V ^a   Niederle, B ^a   Pietschmann, P ^d  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

^c DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

bone metabolism; cathepsin K; gender; OPG; primary hyperparathyroidism; surgery

Indexed keywords

ALKALINE PHOSPHATASE; CALCIUM; CALCIUM ION; CATHEPSIN K; OSTEOPROTEGERIN; PARATHYROID HORMONE; VITAMIN D;

ADULT; ALKALINE PHOSPHATASE BLOOD LEVEL; ARTICLE; BONE DENSITY; BONE METABOLISM; CALCIUM BLOOD LEVEL; CHEMICAL ANALYSIS; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; FEMUR NECK; HUMAN; LUMBAR SPINE; MALE; OSSIFICATION; OSTEOLYSIS; PARATHYROID HORMONE BLOOD LEVEL; PARATHYROIDECTOMY; PRIMARY HYPERPARATHYROIDISM; PRIORITY JOURNAL; PROSPECTIVE STUDY;

ALKALINE PHOSPHATASE; BONE AND BONES; BONE DENSITY; CALCIUM; COLLAGEN TYPE I; DIETARY SUPPLEMENTS; FEMALE; HUMANS; HYPERPARATHYROIDISM, PRIMARY; MALE; MIDDLE AGED; OSTEOCALCIN; PARATHYROID HORMONE; PARATHYROIDECTOMY; PEPTIDES; PHOSPHATES; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; STATISTICS, NONPARAMETRIC; TIME FACTORS; VITAMIN D;

EID: 84861702165     PISSN: 00185043     EISSN: 14394286     Source Type: Journal    
DOI: 10.1055/s-0032-1308998     Document Type: Article

References (31)

1. Eriksen E F, Mosekilde L, Melsen F. Trabecular bone remodeling and balance in primary hyperparathyroidism. Bone: 1986; 7 213 221 (Pubitemid 17171903)
2. Pietschmann P, Niederle B, Anvari A, Woloszczuk W. Serum osteocalcin levels in primary hyperparathyroidism. Klin Wochenschr: 1991; 69 351 353
3. Christiansen P, Steiniche T, Vesterby A, Mosekilde L, Hessov I, Melsen F. Primary hyperparathyroidism: iliac crest trabecular bone volume, structure, remodeling, and balance evaluated by histomorphometric methods. Bone: 1992; 13 41 49
4. Chen Q, Kaji H, Iu M F, Nomura R, Sowa H, Yamauchi M, Tsukamoto T, Sugimoto T, Chihara K. Effects of an excess and a deficiency of endogenous parathyroid hormone on volumetric bone mineral density and bone geometry determined by peripheral quantitative computed tomography in female subjects. J Clin Endocrinol Metab: 2003; 88 4655 4658 (Pubitemid 37357507)
5. Khosla S, Melton L J III, Wermers R A, Crpwsn C S, O'Fallong W M, Riggs B L. Primary hyperparathyroidism and the risk of fracture: a population-based study. J Bone Miner Res: 1999; 14 1700 1707 (Pubitemid 29455818)
6. Gittoes NJ L, Cooper M S. Primary hyperparathyroidism - is mild disease worth treating? Clin Med: 2010; 10 45 49
7. Rauner M, Sipos W, Pietschmann P. Osteoimmunology. Int Arch Allergy Immunol: 2007; 143 31 48 (Pubitemid 46625234)
8. Fraher U, Watson P H, Kisiel M, Natale B V, Hodsman A B. Measurement of circulating osteoprotegerin (OPG) in human sera: inhibition of circulating OPG in osteoporotic patients treated with hPTH (1-34). ASBMR Toronto: 2000; (abstract)
9. Nakchbandi I A, Lang R, Kinder B, Insogna K L. The role of the receptor activator of nuclear factor-kB ligand/osteoprotegerin cytokine system in primary hyperparathyroidism. J Clin Endocrinol Metab: 2008; 93 967 973 (Pubitemid 351398581)
10. Stilgren L S, Hegedüs L M, Beck-Nielsen H, Abrahamsen B. Osteoprotegerin levels in primary hyperparathyroidism: effect of parathyroidectomy and association with bone metabolism. Calcif Tissue Int: 2003; 73 210 216 (Pubitemid 37152880)
11. Stilgren L S, Rettmer E, Hegedüs L M, Beck-Nielsen H, Abrahamsen B. Skeletal changes in osteoprotegerin and receptor activator of nuclear factor-κB ligand mRNA levels in primary hyperparathyroidism: effect of parathyroidectomy and association with bone metabolism. Bone: 2004; 35 256 265 (Pubitemid 38789173)
12. Hesch R D. Die konservative Therapie des extrarenalen Hyperparathyroidismus. In: Beyer J, Krause U. (eds.). Therapie des Hyperparathyroidismus. Stuttart Schattauer: 1981; 51 69
13. Prager G, Czerny C, Kurtaran A, Passler C, Scheuba C, Bieglmayer C, Niederle B. Minimally invasive open parathyroidectomy in an endemic goiter area: a prospective study. Arch Surg: 2001; 36 810 816 (Pubitemid 32642804)
14. Riss P, Kaczirek K, Heinz G, Bieglmayer C, Niederle B. A "defined baselineo" in PTH monitoring increases surgical success in patients with multiple gland disease. Surgery: 2007; 142 398 404 (Pubitemid 47302037)
15. Tanaka Y, Naruse T, Funahashi H, Imai T, Suzumura K, Mase T, Tominaga Y. Bone metabolic analysis in patients with primary hyperparathyroidism. Biomed Pharmacother: 2000; 54 01 97s 99s (Pubitemid 30428899)
16. Garton M, Martin J, Stewart A, Krukowski Z, Matheson N, Robins S, Loveridge N, Reid D. Changes in bone mass and metabolism after surgery for primary hyperparathyroidism. Clin Endocrinol: 1995; 42 493 500
17. Davies C, Demeure M J St, John A, Edis A J. Study of intact (1-84) parathyroid hormone secretion in patients undergoing parathyroidectomy. World J Surg: 1990; 14 355 360 (Pubitemid 20299934)
18. Carty S E, Roberts M M, Virji M A, Haywood L, Yim J H. Elevated serum parathormone level after "concise parathyroidectomyo" for primary sporadic hyperparathyroidism. Surgery: 2002; 132 1086 1093 (Pubitemid 36026959)
19. Biskobing D M. Significance of elevated parathyroid hormone after parathyroidectomy. Endocrine Practice: 2010; 16 112 117
20. Nordenstöm E, Westerdahl J, Bergenfelz A. Long-term follow-up of patients with elevated PTH levels following successful exploration for primary hyperparathyroidism. World J Surg: 2004; 28 570 575 (Pubitemid 38802793)
21. Guo C Y, Holland P A, Jackson B F, Hannon R A, Rogers A, Harrison B J, Eastell R. Immediate changes in biochemical markers of bone turnover and circulating interleukin-6 after parathyroidectomy for primary hyperparathyroidism. Eur J Endocrinol: 2000; 142 451 459 (Pubitemid 30341175)
22. Lumachi F, Ermani M, Basso S M, Camozzi V, Nardi A, Favia G, Luisetto G. Short- and long-term changes in bone mineral density of the lumbar spine after parathyroidectomy in patients with primary hyperthyroidism. Calcif Tissue Int: 2003; 73 44 48 (Pubitemid 37022078)
23. Ominsky M S, Stolina M, Li X, Corbin T J, Asuncion F J, Barrero M, Niu Q T, Dwyer D, Adamu S, Warmington K S, Grisanti M, Tan H L, Ke H Z, Simonet W S, Kostenuik P J. One year of transgenic overexpression of osteoprotegerin in rats suppressed bone resorption and increased vertebral bone volume, density and strength. J Bone Miner Res: 2009; 24 1234 1246
24. Drake M T, Srinivasan B, Mödder U I, Peterson J M, McCready L K, Riggs B L, Dwyer D, Stolina M, Kostenuik P, Khosla S. Effects of parathyroid hormone treatment on circulating sclerostin levels in postmenopausal women. J Clin Endorcinol Metabol: 2010; 95 5056 5062
25. Muñoz-Torres M, Reyes-García R, Mezquita-Raya P, Fernández-García D, Alonso G, Luna Jde D, Ruiz-Requena M E, Escobar-Jiménez F. Serum cathepsin K as a marker of bone metabolism in postmenopausal women treated with alendronate. Maturitas: 2009; 64 188 192
26. Christiansen P, Steiniche T, Brixen K, Hessov I, Melsen F, Heickendorff L, Mosekilde L. Primary hyperparathyroidism: short-term changes in bone remodeling and bone mineral density following parathyroidectomy. Bone: 1999; 25 237 244 (Pubitemid 29317628)
27. Hagström E, Lundgren E, Mallmin H, Rastad J, Hellman P. Positive effect of parathyroidectomy on bone mineral density in mild asymptomatic primary hyperparathyroidism. J Int Med: 2006; 259 191 198
28. Sitges-Serra A, Prieto R, Pena M J, Nogues X, Sancho J J. Effect of parathyroidectomy for primary hyperparathyroidism on bone mineral density in postmenopausal women. Br J Surg: 2010; 97 1013 1019
29. Lumachi F, Camozzi V, Ermani M, Naradi A, Luisetto G. Lumbar spine bone mineral density changes in patients with primary hyperparathyroidism according to age and gender. Ann NY Acad Sci: 2007; 1117 362 366 (Pubitemid 350191273)
30. Eriksen E F. Primary hyperparathyroidism: lessons from bone histomorphometry. JBMR: 2002; 17 N95 N97 (Pubitemid 35222319)
31. Siilin H, Lundgren E, Mallmin H, Mellström D, Ohlsson C, Karlsson M, Orwoll E, Ljunggren O. Prevalence of primary hyperparathyroidism and impact on bone mineral density in elderly men: MrOs Sweden. World J Surg 2011; 35 1266 1272