Mutations in human nonmuscle myosin IIA found in patients with May-Hegglin anomaly and Fechtner syndrome result in impaired enzymatic function

Journal of Biological Chemistry

Volumn 277, Issue 48, 2002, Pages 46512-46517

  Hu, Aihua ^a   Wang, Fei ^a   Sellers, James R ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONFORMATIONS; DISEASES; GENES; MUSCLE; VIRUSES;

PLATELETES;

BIOCHEMISTRY;

ACTIN; ADENOSINE TRIPHOSPHATASE (MAGNESIUM); MEROMYOSIN; MYOSIN HEAVY CHAIN; MYOSIN IIA;

ACTIN FILAMENT; ARTICLE; AUTOSOMAL DOMINANT DISORDER; BACULOVIRUS; CHEMICAL ANALYSIS; ENZYME ACTIVITY; ENZYME DEFECT; ENZYME MECHANISM; FECHTNER SYNDROME; GENE MUTATION; MAY HEGGLIN ANOMALY; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN ENGINEERING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; STRUCTURE ANALYSIS; THROMBOCYTE DISORDER;

BASE SEQUENCE; DNA PRIMERS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HUMANS; MODELS, MOLECULAR; MUTATION; NONMUSCLE MYOSIN TYPE IIA; PHOSPHORYLATION; SYNDROME; THROMBOCYTOPENIA;

UNIDENTIFIED BACULOVIRUS; VERTEBRATA;

EID: 0037195954     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M208506200     Document Type: Article

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