Synthesis and biological evaluation of 9-alkoxy-6,7-dihydro-5H-benzo[c] [1,2,4]triazolo[4,3-a]azepines as potential anticonvulsant agents

Arzneimittel-Forschung/Drug Research

Volumn 62, Issue 4, 2012, Pages 202-207

  Piao, F Y ^a   Peng, B ^a   Zhang, W B ^a   Zhang, W ^a   Han, R B ^a  

^a YANBIAN UNIVERSITY   (China)

Author keywords

anticonvulsant activity; benzotriazoloazepine; synthesis

Indexed keywords

4 AMINOBUTYRATE AMINOTRANSFERASE; 9 HEXYLOXY 6,7 DIHYDRO 5H BENZO[C][1,2,4]TRIAZOLO[4,3 A]AZEPINE; 9 PENTYLOXY 6,7 DIHYDRO 5H BENZO[C][1,2,4]TRIAZOLO[4,3 A]AZEPINE; ANTICONVULSIVE AGENT; AZEPINE DERIVATIVE; CARBAMAZEPINE; GLUTAMATE DECARBOXYLASE; PENTETRAZOLE; PHENOBARBITAL; PHENYTOIN; TRIAZOLE DERIVATIVE; UNCLASSIFIED DRUG; VALPROIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; EXPERIMENTAL TEST; MASS SPECTROMETRY; MAXIMAL ELECTROSHOCK TEST; MOUSE; NEUROTOXICITY; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE; ROTAROD TEST; SEIZURE; STRUCTURE ACTIVITY RELATION; TOXICITY TESTING;

ANIMALS; ANTICONVULSANTS; AZEPINES; CONVULSANTS; ELECTROSHOCK; MICE; PENTYLENETETRAZOLE; POSTURAL BALANCE; SEIZURES; SPECTROPHOTOMETRY, INFRARED; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

EID: 84861695485     PISSN: 00044172     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0031-1301295     Document Type: Article

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