Anti-tumor activity of a new series of benzoxazepine derivatives in breast cancer

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 1, 2010, Pages 283-287

  Samanta, Krishnananda ^a   Chakravarti, Bandana ^a   Mishra, Jitendra Kumar ^a   Dwivedi, Shailendra Kumar Dhar ^a   Nayak, Lakshma Vadithe ^a   Choudhry, Preeti ^a   Bid, Hemant Kumar ^a   Konwar, Rituraj ^a   Chattopadhyay, Naibedya ^a   Panda, Gautam ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Amino acids; Anti tumor activity; Benzoxazepines derivatives; Breast cancer; Intramolecular Mitsunobu cyclization

Indexed keywords

BENZOXAZEPINE DERIVATIVE; OXAZEPINE DERIVATIVE; TAMOXIFEN CITRATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL STRAIN HEK293; CELL STRAIN MCF 7; CONTROLLED STUDY; CYCLIZATION; CYTOTOXICITY; DEBENZYLATION; DRUG IDENTIFICATION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; MITSUNOBU REACTION; MOUSE; NONHUMAN; TREATMENT DURATION; TUMOR VOLUME; TUMOR XENOGRAFT;

ALUMINUM COMPOUNDS; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BREAST NEOPLASMS; CELL LINE, TUMOR; CYCLIZATION; FEMALE; G0 PHASE; G1 PHASE; HUMANS; LITHIUM COMPOUNDS; MICE; MICE, NUDE; OXAZEPINES; STRUCTURE-ACTIVITY RELATIONSHIP; TAMOXIFEN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

MUS MUSCULUS;

EID: 72049103142     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.10.115     Document Type: Article

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