Pediatric high grade glioma of the spinal cord: Results of the HIT-GBM database

Journal of Neuro-Oncology

Volumn 107, Issue 1, 2012, Pages 139-146

  Wolff, Birte ^a   Ng, Ann ^a   Roth, Daniela ^b   Parthey, Kathleen ^b   Warmuth Metz, Monika ^c   Eyrich, Matthias ^d   Kordes, Uwe ^e   Kortmann, Rolf ^f   Pietsch, Torsten ^g   Kramm, Christof ^h   Wolff, Johannes E A ⁱ  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

^e UNIVERSITY OF HAMBURG   (Germany)

^f UNIVERSITY OF LEIPZIG   (Germany)

^g UNIVERSITY OF BONN   (Germany)

^h MARTIN LUTHER UNIVERSITÄT HALLE WITTENBERG   (Germany)

ⁱ TUFTS MEDICAL CENTER   (United States)

Author keywords

GBM; Gross total resection; HIT GBM database; Pediatric high grade glioma; Spinal cord

Indexed keywords

ANTINEOPLASTIC AGENT;

ADULT; ARTICLE; CANCER CHEMOTHERAPY; CANCER CLASSIFICATION; CANCER DIAGNOSIS; CANCER GRADING; CANCER LOCALIZATION; CANCER PATIENT; CANCER PROGNOSIS; CANCER RADIOTHERAPY; CANCER SIZE; CANCER SURGERY; CANCER SURVIVAL; CHEMORADIOTHERAPY; CHILDHOOD CANCER; CLINICAL ARTICLE; CONTROLLED STUDY; DATA BASE; EUROPE; FEMALE; FOLLOW UP; GLIOMA; HISTOPATHOLOGY; HIT GBM DATABASE; HUMAN; HUMAN TISSUE; MALE; OVERALL SURVIVAL; RETROSPECTIVE STUDY; SPINAL CORD BIOPSY; SPINAL CORD CANCER; SPINAL CORD SURGERY; SURVIVAL TIME; TUMOR NECROSIS; VERTEBRA; WORLD HEALTH ORGANIZATION; ADOLESCENT; CHILD; FACTUAL DATABASE; INFANT; METASTASIS; MORTALITY; PATHOLOGY; PRESCHOOL CHILD; PROGNOSIS; SPINAL CORD TUMOR; SURVIVAL RATE;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; DATABASES, FACTUAL; FEMALE; FOLLOW-UP STUDIES; GLIOMA; HUMANS; INFANT; MALE; NEOPLASM METASTASIS; PROGNOSIS; RETROSPECTIVE STUDIES; SPINAL CORD NEOPLASMS; SURVIVAL RATE;

EID: 84861665939     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-011-0718-y     Document Type: Article

References (27)

1. Bouffet E, Pierre-Kahn A, Marchal JC, Jouvet A, Kalifa C, Choux M, Dhellemmes P, Guerin J, Tremoulet M, Mottolese C (1998) Prognostic factors in pediatric spinal cord astrocytoma. Cancer 83(11):2391-2399. doi:10.1002/(SICI) 1097-0142(1998 1201)83:11\2391:AID-CNCR20[3.0.CO;2-0
2. Cristante L, Herrmann HD (1994) Surgical management of intramedullary spinal cord tumors: functional outcome and sources of morbidity. Neurosurgery 35(1):69-74 discussion 74-66
3. Epstein FJ, Farmer JP (1990) Pediatric spinal cord tumor surgery. Neurosurg Clin N Am 1(3):569-590
4. Allen JC, Aviner S, Yates AJ, Boyett JM, Cherlow JM, Turski PA, Epstein F, Finlay JL (1998) Treatment of high-grade spinal cord astrocytoma of childhood with "8-in-1" chemotherapy and radiotherapy: a pilot study of CCG-945. Children's Cancer Group. J Neurosurg 88(2):215-220. doi:10.3171/jns.1998.88.2.0215
5. Wolff JE, Classen CF, Wagner S, Kortmann RD, Palla SL, Pietsch T, Kuhl J, Gnekow A, Kramm CM (2008) Subpopulations of malignant gliomas in pediatric patients: analysis of the HIT-GBM database. J Neurooncol 87(2):155-164. doi:10.1007/s11060- 007-9495-z
6. Kramm CM, Wagner S, Van Gool S, Schmid H, Strater R, Gnekow A, Rutkowski S, Wolff JE (2006) Improved survival after gross total resection of malignant gliomas in pediatric patients from the HIT-GBM studies. Anticancer Res 26(5B):3773-3779
7. Constantini S, Houten J, Miller DC, Freed D, Ozek MM, Rorke LB, Allen JC, Epstein FJ (1996) Intramedullary spinal cord tumors in children under the age of 3 years. J Neurosurg 85(6):1036-1043. doi:10.3171/jns.1996.85.6.1036
8. McGirt MJ, Chaichana KL, Atiba A, Attenello F, Woodworth GF, Jallo GI (2008) Neurological outcome after resection of intramedullary spinal cord tumors in children. Childs Nerv Syst 24(1):93-97. doi:10.1007/s00381-007-0446-y
9. Reimer R, Onofrio BM (1985) Astrocytomas of the spinal cord in children and adolescents. J Neurosurg 63(5):669-675. doi:10.3171/jns.1985.63.5.0669
10. McGirt MJ, Goldstein IM, Chaichana KL, Tobias ME, Kothbauer KF, Jallo GI (2008) Extent of surgical resection of malignant astrocytomas of the spinal cord: outcome analysis of 35 patients. Neurosurgery 63(1):55-60. doi:10.1227/01.NEU.0000335070. 37943.09 discussion 60-51
11. Constantini S, Miller DC, Allen JC, Rorke LB, Freed D, Epstein FJ (2000) Radical excision of intramedullary spinal cord tumors: surgical morbidity and long-term follow-up evaluation in 164 children and young adults. J Neurosurg 93(2):183-193
12. Wolff JE, Driever PH, Erdlenbruch B, Kortmann RD, Rutkowski S, Pietsch T, Parker C, Metz MW, Gnekow A, Kramm CM (2010) Intensive chemotherapy improves survival in pediatric high-grade glioma after gross total resection: results of the HIT-GBM-C protocol. Cancer 116(3):705-712. doi:10.1002/cncr.24730
13. Karremann M, Pietsch T, Janssen G, Kramm CM, Wolff JE (2009) Anaplastic ganglioglioma in children. J Neurooncol 92(2):157-163. doi:10.1007/s11060-008- 9747-6
14. Benesch M, Wagner S, Berthold F, Wolff JE (2005) Primary dissemination of high-grade gliomas in children: experiences from four studies of the Pediatric Oncology and Hematology Society of the German Language Group (GPOH). J Neurooncol 72(2):179-183. doi:10.1007/s11060-004-3546-5
15. Classen CF, Warmuth-Metz M, Papke K, Trotter A, Wolff JE, Wagner S (2006) Late response to radiochemotherapy in pediatric glioblastoma: report on two patients treated according to HITGBM protocols. Pediatr Hematol Oncol 23(8):631-637. doi:10.1080/08880010600951088
16. Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW, Kleihues P (2007) The 2007 WHO classification of tumours of the central nervous system. Acta Neuropathol 114(2):97-109
17. Rutkowski S, Bode U, Deinlein F, Ottensmeier H, Warmuth- Metz M, Soerensen N, Graf N, Emser A, Pietsch T, Wolff JE, Kortmann RD, Kuehl J (2005) Treatment of early childhood medulloblastoma by postoperative chemotherapy alone. N Engl J Med 352(10):978-986. doi:10.1056/NEJMoa042176
18. Wolff JE, Kortmann RD, Wolff B, Pietsch T, Peters O, Schmid HJ, Rutkowski S, Warmuth-Metz M, Kramm C (2011) High dose methotrexate for pediatric high grade glioma: results of the HITGBM- D pilot study. J Neurooncol 102(3):433-442. doi:10.1007/s11060-010-0334-2
19. Wagner S, Warmuth-Metz M, Emser A, Gnekow AK, Strater R, Rutkowski S, Jorch N, Schmid HJ, Berthold F, Graf N, Kortmann RD, Pietsch T, Sorensen N, Peters O, Wolff JE (2006) Treatment options in childhood pontine gliomas. J Neurooncol 79(3):281-287. doi:10.1007/s11060-006-9133-1
20. Packer RJ (1994) Diagnosis and treatment of pediatric brain tumors. Curr Opin Neurol 7(6):484-491
21. Cohen AR, Wisoff JH, Allen JC, Epstein F (1989) Malignant astrocytomas of the spinal cord. J Neurosurg 70(1):50-54. doi:10.3171/jns.1989.70.1.0050
22. Rossitch E Jr, Zeidman SM, Burger PC, Curnes JT, Harsh C, Anscher M, Oakes WJ (1990) Clinical and pathological analysis of spinal cord astrocytomas in children. Neurosurgery 27(2):193-196
23. Guidetti B, Mercuri S, Vagnozzi R (1981) Long-term results of the surgical treatment of 129 intramedullary spinal gliomas. J Neurosurg 54(3):323-330. doi:10.3171/jns.1981.54.3.0323
24. Hargrave DR, Zacharoulis S (2007) Pediatric CNS tumors: current treatment and future directions. Expert Rev Neurother 7(8):1029-1042. doi:10.1586/14737175.7.8.1029
25. Crawford JR, Zaninovic A, Santi M, Rushing EJ, Olsen CH, Keating RF, Vezina G, Kadom N, Packer RJ (2009) Primary spinal cord tumors of childhood: effects of clinical presentation, radiographic features, and pathology on survival. J Neurooncol 95(2):259-269. doi:10.1007/s11060-009-9925-1
26. Houten JK, Weiner HL (2000) Pediatric intramedullary spinal cord tumors: special considerations. J Neurooncol 47(3):225-230
27. Wolff JE, Mohiuddin K, Jorch N, Graf N, Wagner S, Vats T, Gnekow A (2010) Measuring performance status in pediatric patients with brain tumors-experience of the HIT-GBM-C protocol. Pediatr Blood Cancer 55(3):520-524. doi:10.1002/pbc.22566