Differential signature of fecal microRNAs in patients with pancreatic cancer

Molecular Medicine Reports

Volumn 6, Issue 1, 2012, Pages 201-209

  Ren, Yan ^a   Gao, Jun ^a   Liu, Jian Qiang ^a   Wang, Xiao Wei ^a   Gu, Jun Jun ^a   Huang, Hao Jie ^a   Gong, Yan Fang ^a   Li, Zhao Shen ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Diagnosis; Fecal microRNAs; Pancreatic cancer

Indexed keywords

BIOLOGICAL MARKER; MICRORNA; MICRORNA 181B; MICRORNA 196A; MICRORNA 210; MOLECULAR MARKER; UNCLASSIFIED DRUG;

ARTICLE; CANCER PATIENT; CANCER SCREENING; CHRONIC PANCREATITIS; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DIAGNOSTIC VALUE; EARLY DIAGNOSIS; FECES ANALYSIS; FEMALE; GENE EXPRESSION; HUMAN; MALE; NON INVASIVE PROCEDURE; PANCREAS CANCER; REPRODUCIBILITY; RNA ISOLATION; TUMOR VOLUME; VALIDATION PROCESS;

ADULT; AGED; EARLY DETECTION OF CANCER; FECES; FEMALE; GENE EXPRESSION PROFILING; HUMANS; MALE; MICRORNAS; MIDDLE AGED; PANCREATIC NEOPLASMS; REPRODUCIBILITY OF RESULTS; TUMOR MARKERS, BIOLOGICAL;

EID: 84861650980     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2012.862     Document Type: Article

References (35)

1. Real FX: A 'catastrophic hypothesis' for pancreas cancer progression. Gastroenterology 124: 1958-1964, 2003.
2. Wade TP, Halaby IA, Stapleton DR, Virgo KS and Johnson FE: Population-based analysis of treatment of pancreatic cancer and Whipple resection: Department of Defense Hospitals, 1989-1994. Surgery 120: 680-687, 1996. (Pubitemid 26334324)
3. Bartel DP: MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297, 2004.
4. Carrington JC and Ambros V: Role of microRNAs in plant and animal development. Science 301: 336-338, 2003. (Pubitemid 36877060)
5. Lim LP, Glasner ME, Yekta S, Burge CB and Bartel DP: Vertebrate microRNA genes. Science 299: 1540, 2003. (Pubitemid 36297696)
6. Lim LP, Lau NC, Weinstein EG, et al: The microRNAs of Caenorhabditis elegans. Genes Dev 17: 991-1008, 2003. (Pubitemid 36459452)
7. Ambros V: microRNA pathways in flies and worms: growth, death, fat, stress, and timing. Cell 113: 673-676, 2003.
8. Ke XS, Liu CM, Liu DP and Liang CC: microRNAs: key participants in gene regulatory networks. Curr Opin Chem Biol 7: 516-523, 2003.
9. Bartel B and Bartel DP: microRNAs: at the root of plant development? Plant Physiol 132: 709-717, 2003. (Pubitemid 36715068)
10. Chen X, Ba Y, Ma L, et al: Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases. Cell Res 18: 997-1006, 2008.
11. Hui AB, Shi W, Boutros PC, et al: Robust global microRNA profiling with formalin-fixed paraffin-embedded breast cancer tissues. Lab Invest 89: 597-606, 2009.
12. Mitchell PS, Parkin RK, Kroh EM, et al: Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci USA 105: 10513-10518, 2008.
13. Lu J, Getz G, Miska EA, et al: microRNA expression profiles classify human cancers. Nature 435: 834-838, 2005. (Pubitemid 40839735)
14. He H, Jazdzewski K, Li W, et al: The role of microRNA genes in papillary thyroid carcinoma. Proc Natl Acad Sci USA 102: 19075-19080, 2005. (Pubitemid 43049568)
15. Iorio MV, Ferracin M, Liu CG, et al: microRNA gene expression deregulation in human breast cancer. Cancer Res 65: 7065-7070, 2005. (Pubitemid 41161233)
16. Murakami Y, Yasuda T, Saigo K, et al: Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues. Oncogene 25: 2537-2545, 2006.
17. Roldo C, Missiaglia E, Hagan JP, et al: microRNA expression abnormalities in pancreatic endocrine and acinar tumors are associated with distinctive pathologic features and clinical behavior. J Clin Oncol 24: 4677-4684, 2006. (Pubitemid 46630931)
18. Vandesompele J, De Preter K, Pattyn F, et al: Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3: RESEARCH0034, 2002.
19. Yanaihara N, Caplen N, Bowman E, et al: Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell 9: 189-198, 2006. (Pubitemid 43357945)
20. Hanke M, Hoefig K, Merz H, et al: A robust methodology to study urine microRNA as tumor marker: microRNA-126 and microRNA-182 are related to urinary bladder cancer. Urol Oncol 28: 655-661, 2010.
21. Link A, Balaguer F, Shen Y, et al: Fecal microRNAs as novel biomarkers for colon cancer screening. Cancer Epidemiol Biomarkers Prev 19: 1766-1774, 2010.
22. Kawarada Y: New classification of pancreatic carcinoma - apan Pancreas Society. Nihon Shokakibyo Gakkai Zasshi 100: 974-980, 2003 (In Japanese).
23. Bhatt K, Zhou L, Mi QS, Huang S, She JX and Dong Z: microRNA-34a is induced via p53 during cisplatin nephrotoxicity and contributes to cell survival. Mol Med 16: 409-416, 2010.
24. Dillhoff M, Liu J, Frankel W, Croce C and Bloomston M: microRNA-21 is overexpressed in pancreatic cancer and a potential predictor of survival. J Gastrointest Surg 12: 2171-2176, 2008.
25. Lee EJ, Gusev Y, Jiang J, et al: Expression profiling identifies microRNA signature in pancreatic cancer. Int J Cancer 120: 1046-1054, 2007. (Pubitemid 46214304)
26. Volinia S, Calin GA, Liu CG, et al: A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 103: 2257-2261, 2006. (Pubitemid 43271657)
27. Lynam-Lennon N, Maher SG and Reynolds JV: The roles of microRNA in cancer and apoptosis. Biol Rev Camb Philos Soc 84: 55-71, 2009.
28. Bloomston M, Frankel WL, Petrocca F, et al: microRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis. JAMA 297: 1901-1908, 2007. (Pubitemid 46707844)
29. Szafranska AE, Davison TS, John J, et al: microRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma. Oncogene 26: 4442-4452, 2007. (Pubitemid 47014466)
30. Greither T, Grochola LF, Udelnow A, Lautenschlager C, Wurl P and Taubert H: Elevated expression of microRNAs 155, 203, 210 and 222 in pancreatic tumors is associated with poorer survival. Int J Cancer 126: 73-80, 2010.
31. Mardin WA and Mees ST: microRNAs: novel diagnostic and therapeutic tools for pancreatic ductal adenocarcinoma? Ann Surg Oncol 16: 3183-3189, 2009.
32. Szafranska AE, Doleshal M, Edmunds HS, et al: Analysis of microRNAs in pancreatic fine-needle aspirates can classify benign and malignant tissues. Clin Chem 54: 1716-1724, 2008.
33. Zhang Y, Li M, Wang H, et al: Profiling of 95 microRNAs in pancreatic cancer cell lines and surgical specimens by real-time PCR analysis. World J Surg 33: 698-709, 2009.
34. Kong X, Du Y, Wang G, et al: Detection of differentially expressed microRNAs in serum of pancreatic ductal adenocarcinoma patients: miR-196a could be a potential marker for poor prognosis. Dig Dis Sci 56: 602-609, 2011.
35. Taylor DD and Gercel-Taylor C: microRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Gynecol Oncol 110: 13-21, 2008. (Pubitemid 351853251)