Thiol-ene-based biological/synthetic hybrid biomatrix for 3-D living cell culture

Acta Biomaterialia

Volumn 8, Issue 7, 2012, Pages 2504-2516

  Xu, Kedi ^a   Fu, Yao ^a   Chung, Weiju ^b   Zheng, Xiaoxiang ^c   Cui, Yujia ^b   Hsu, Ian C ^b   Kao, Weiyuan John ^a,d,e  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b NATIONAL TSING HUA UNIVERSITY   (Taiwan)

^c ZHEJIANG UNIVERSITY   (China)

^d University of Wisconsin Madison   (United States)

^e UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Bioactivity; Biomatrix; Cell encapsulation; Gelatin; Poly(ethylene glycol)

Indexed keywords

AMINO ACIDS; CELL CULTURE; CELLS; CROSSLINKING; DISSOLUTION; ETHYLENE GLYCOL; HYBRID MATERIALS; HYDROGELS; POLYOLS; SCAFFOLDS (BIOLOGY); SWELLING; TISSUE; VISCOELASTICITY;

BIOFUNCTIONALITY; BIOMATRIX; CELL ENCAPSULATIONS; DIACRYLATES; GELATIN; LIVING CELL; MATRIX; PROPERTY; SYNTHETIC MATERIALS; THIOL/ENE;

POLYETHYLENE GLYCOLS;

ACRYLIC ACID COPOLYMER; COLLAGENASE; CYSTEINE; GELATIN; MACROGOL; THIOL; TISSUE SCAFFOLD;

ARTICLE; BIODEGRADATION; CELL ADHESION; CELL CULTURE; CELL DENSITY; CELL ENCAPSULATION; CELL FUNCTION; CELL PROLIFERATION; CONCENTRATION (PARAMETERS); COVALENT BOND; CROSS LINKING; CYTOPLASM; DISSOLUTION; FIBROBLAST; HUMAN; HUMAN CELL; HYBRID; HYDROGEL; KERATINOCYTE; PRIORITY JOURNAL; THREE DIMENSIONAL IMAGING; VISCOELASTICITY; WATER CONTENT;

EID: 84861648104     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2012.03.049     Document Type: Article

References (38)

1. M.P. Lutolf, and J.A. Hubbell Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering Nat Biotechnol 23 1 2005 47 55
2. J.L. Drury, and D.J. Mooney Hydrogels for tissue engineering: scaffold design variables and applications Biomaterials 24 24 2003 4337 4351
3. L.G. Griffith, and G. Naughton Tissue engineering - current challenges and expanding opportunities Science 295 5557 2002 1009 1014
4. C.R. Nuttelman, M.A. Rice, A.E. Rydholm, C.N. Salinas, D.N. Shah, and K.S. Anseth Macromolecular monomers for the synthesis of hydrogel niches and their application in cell encapsulation and tissue engineering Prog Polym Sci 33 2 2008 167 179
5. J.L. Ifkovits, and J.A. Burdick Review: photopolymerizable and degradable biomaterials for tissue engineering applications Tissue Eng 13 10 2007 2369 2385
6. M.C. Cushing, and K.S. Anseth Materials science. Hydrogel cell cultures Science 316 5828 2007 1133 1134
7. E. Dawson, G. Mapili, K. Erickson, S. Taqvi, and K. Roy Biomaterials for stem cell differentiation Adv Drug Deliv Rev 60 2 2008 215 228
8. J.A. Burmania, K.R. Stevens, and W.J. Kao Cell interaction with protein-loaded interpenetrating networks containing modified gelatin and poly(ethylene glycol) diacrylate Biomaterials 24 22 2003 3921 3930
9. Y. Fu, K. Xu, X. Zheng, A.J. Giacomin, A.W. Mix, and W.J. Kao 3D cell entrapment in crosslinked thiolated gelatin-poly(ethylene glycol) diacrylate hydrogels Biomaterials 33 1 2011 48 58
10. S.-H. Hsu, and A.M. Jamieson Viscoelastic behaviour at the thermal sol-gel transition of gelatin Polymer 34 12 1993 2602 2608
11. Waldeck H, Kao WJ. Effect of the addition of a labile gelatin component on the degradation and solute release kinetics of a stable PEG hydrogel. J Biomater Sci Polym Ed 2011. http://dx.doi.org/10.1163/092050611X587547.
12. J.W. Mwangi, and C.M. Ofner IIIrd. Crosslinked gelatin matrices: release of a random coil macromolecular solute Int J Pharm 278 2 2004 319 327
13. J.A. Benton, C.A. DeForest, V. Vivekanandan, and K.S. Anseth Photocrosslinking of gelatin macromers to synthesize porous hydrogels that promote valvular interstitial cell function Tissue Eng. Part A 15 11 2009 3221 3230
14. J.W. Nichol, S.T. Koshy, H. Bae, C.M. Hwang, S. Yamanlar, and A. Khademhosseini Cell-laden microengineered gelatin methacrylate hydrogels Biomaterials 31 21 2010 5536 5544
15. F. Brandl, F. Sommer, and A. Goepferich Rational design of hydrogels for tissue engineering: impact of physical factors on cell behavior Biomaterials 28 2 2007 134 146
16. R.H. Li, D.H. Altreuter, and F.T. Gentile Transport characterization of hydrogel matrices for cell encapsulation Biotechnol Bioeng 50 4 1996 365 373
17. S.H. Parekh, K. Chatterjee, S. Lin-Gibson, N.M. Moore, M.T. Cicerone, and M.F. Young Modulus-driven differentiation of marrow stromal cells in 3D scaffolds that is independent of myosin-based cytoskeletal tension Biomaterials 32 9 2011 2256 2264
18. D. Dikovsky, H. Bianco-Peled, and D. Seliktar The effect of structural alterations of PEG-fibrinogen hydrogel scaffolds on 3-D cellular morphology and cellular migration Biomaterials 27 8 2006 1496 1506
19. L. Almany, and D. Seliktar Biosynthetic hydrogel scaffolds made from fibrinogen and polyethylene glycol for 3D cell cultures Biomaterials 26 15 2005 2467 2477
20. C.B. Hutson, J.W. Nichol, H. Aubin, H. Bae, S. Yamanlar, and S. Al-Haque Synthesis and characterization of tunable poly(ethylene glycol): gelatin methacrylate composite hydrogels Tissue Eng. Part A 17 13-14 2011 1713 1723
21. M. Gonen-Wadmany, R. Goldshmid, and D. Seliktar Biological and mechanical implications of PEGylating proteins into hydrogel biomaterials Biomaterials 32 26 2011 6025 6033
22. D.R. Schmidt, and W.J. Kao Monocyte activation in response to polyethylene glycol hydrogels grafted with RGD and PHSRN separated by interpositional spacers of various lengths J Biomed Mater Res A 83 3 2007 617 625
23. T. Miron, and M. Wilchek A simplified method for the preparation of succinimidyl carbonate polyethylene glycol for coupling to proteins Bioconjug Chem 4 6 1993 568 569
24. J.K. Armstrong, R.B. Wenby, H.J. Meiselman, and T.C. Fisher The hydrodynamic radii of macromolecules and their effect on red blood cell aggregation Biophys J 87 2004 4259 4270
25. Y. Tabata, and Y. Ikada Vascularization effect of basic fibroblast growth factor released from gelatin hydrogels with different biodegradabilities Biomaterials 20 22 1999 2169 2175
26. T.-S. Yang, Y. Cui, C.-M. Wu, J.-M. Lo, C.-S. Chiang, and W.-Y. Shu Determining the zero-force binding energetics of an intercalated DNA complex by a single-molecule approach Chem Phys Chem 10 16 2009 2791 2794
27. M.C. Wang, and G.E. Uhlenbeck On the theory of the Brownian motion II Rev Mod Phys 17 2-3 1945 323 342
28. A. Chung, Q. Gao, and W.J. Kao Macrophage matrix metalloproteinase-2/-9 gene and protein expression following adhesion to ECM-derived multifunctional matrices via integrin complexation Biomaterials 28 2 2007 285 298
29. N.B. Cramer, and C.N. Bowman Kinetics of thiol-ene and thiol-acrylate photopolymerizations with real-time fourier transform infrared J Polym Sci. Part A. Polym Chem 39 19 2001 3311 3319
30. C.N. Salinas, and K.S. Anseth Mixed mode thiol-acrylate photopolymerizations for the synthesis of PEG-peptide hydrogels Macromolecules 41 16 2008 6019 6026
31. A.E. Rydholm, S.K. Reddy, K.S. Anseth, and C.N. Bowman Controlling network structure in degradable thiol-acrylate biomaterials to tune mass loss behavior Biomacromolecules 7 10 2006 2827 2836
32. D. Calvet, J.Y. Wong, and S. Giasson Rheological monitoring of polyacrylamide gelation: importance of cross-link density and temperature Macromolecules 37 20 2004 7762 7771
33. R.L. Mauck, S.L. Seyhan, G.A. Ateshian, and C.T. Hung Influence of seeding density and dynamic deformational loading on the developing structure/function relationships of chondrocyte-seeded agarose hydrogels Ann Biomed Eng 30 8 2002 1046 1056
34. N.C. Padmavathi, and P.R. Chatterji Structural characteristics and swelling behavior of poly(ethylene glycol) diacrylate hydrogels Macromolecules 29 6 1996 1976 1979
35. R.P. Witte, A.J. Blake, C. Palmer, and W.J. Kao Analysis of poly(ethylene glycol)-diacrylate macromer polymerization within a multicomponent semi-interpenetrating polymer network system J Biomed Mater Res. Part A 71A 3 2004 508 518
36. S.R. Peyton, C.B. Raub, V.P. Keschrumrus, and A.J. Putnam The use of poly(ethylene glycol) hydrogels to investigate the impact of ECM chemistry and mechanics on smooth muscle cells Biomaterials 27 28 2006 4881 4893
37. K. Ghosh, Z. Pan, E. Guan, S. Ge, Y. Liu, and T. Nakamura Cell adaptation to a physiologically relevant ECM mimic with different viscoelastic properties Biomaterials 28 4 2007 671 679
38. K.E. Lewus, and E.A. Nauman In vitro characterization of a bone marrow stem cell-seeded collagen gel composite for soft tissue grafts: effects of fiber number and serum concentration Tissue Eng 11 7-8 2005 1015 1022