Relationship between serum antibody titres to Porphyromonas gingivalis and hs-CRP levels as inflammatory markers of periodontitis

Archives of Oral Biology

Volumn 57, Issue 6, 2012, Pages 820-829

  Miyashita, Hirotaka ^a,b   Honda, Tomoyuki ^a,b   Maekawa, Tomoki ^a,b   Takahashi, Naoki ^a,b   Aoki, Yukari ^a,b   Nakajima, Takako ^a,c   Tabeta, Koichi ^a   Yamazaki, Kazuhisa ^a,b  

^a NIIGATA UNIVERSITY   (Japan)

^b NIIGATA UNIVERSITY GRADUATE SCHOOL OF MEDICAL AND DENTAL SCIENCES   (Japan)

^c NIIGATA UNIVERSITY MEDICAL AND DENTAL HOSPITAL   (Japan)

Author keywords

Antibody; CRP; Periodontitis; Porphyromonas gingivalis

Indexed keywords

BACTERIUM ANTIBODY; BIOLOGICAL MARKER; C REACTIVE PROTEIN;

ANALYSIS OF VARIANCE; ARTICLE; BLOOD; CASE CONTROL STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; IMMUNOLOGY; JAPAN; MALE; METABOLISM; MICROBIOLOGY; MIDDLE AGED; NONPARAMETRIC TEST; PERIODONTICS; PERIODONTITIS; PORPHYROMONAS GINGIVALIS; REGRESSION ANALYSIS;

ANALYSIS OF VARIANCE; ANTIBODIES, BACTERIAL; BIOLOGICAL MARKERS; C-REACTIVE PROTEIN; CASE-CONTROL STUDIES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; JAPAN; MALE; MIDDLE AGED; PERIODONTAL INDEX; PERIODONTITIS; PORPHYROMONAS GINGIVALIS; REGRESSION ANALYSIS; STATISTICS, NONPARAMETRIC;

PORPHYROMONAS GINGIVALIS;

EID: 84861642107     PISSN: 00039969     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.archoralbio.2011.11.008     Document Type: Article

References (41)

1. F. DeStefano, R.F. Anda, H.S. Kahn, D.F. Williamson, and C.M. Russell Dental disease and risk of coronary heart disease and mortality BMJ 306 March (6879) 1993 688 691
2. A.J. Grau, F. Buggle, C. Ziegler, W. Schwarz, J. Meuser, and A.J. Tasman Association between acute cerebrovascular ischemia and chronic and recurrent infection Stroke 28 September (9) 1997 1724 1729
3. K.J. Mattila, V.V. Valtonen, M. Nieminen, and J.K. Huttunen Dental infection and the risk of new coronary events: prospective study of patients with documented coronary artery disease Clin Infect Dis 20 March (3) 1995 588 592
4. P.J. Pussinen, G. Alfthan, H. Rissanen, A. Reunanen, S. Asikainen, and P. Knekt Antibodies to periodontal pathogens and stroke risk Stroke 35 September (9) 2004 2020 2023
5. R. Ross Atherosclerosis - an inflammatory disease N Engl J Med 340 January (2) 1999 115 126
6. Z.S. Galis, G.K. Sukhova, M.W. Lark, and P. Libby Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques J Clin Invest 94 Decemeber (6) 1994 2493 2503
7. F.L. Ruberg, J.A. Leopold, and J. Loscalzo Atherothrombosis: plaque instability and thrombogenesis Prog Cardiovasc Dis 44 March-April (5) 2002 381 394
8. R. Liu, M. Yamamoto, M. Moroi, T. Kubota, T. Ono, and A. Funatsu Chlamydia pneumoniae immunoreactivity in coronary artery plaques of patients with acute coronary syndromes and its relation with serology Am Heart J 150 October (4) 2005 681 688
9. G.R. Persson, and R.E. Persson Cardiovascular disease and periodontitis: an update on the associations and risk J Clin Periodontol 35 September (8 Suppl.) 2008 362 379
10. M.B. Pepys, and G.M. Hirschfield C-reactive protein: a critical update J Clin Invest 111 June (12) 2003 1805 1812
11. P.M. Ridker C-reactive protein and the prediction of cardiovascular events among those at intermediate risk: moving an inflammatory hypothesis toward consensus J Am Coll Cardiol 49 May (21) 2007 2129 2138
12. P.M. Ridker, C.H. Hennekens, J.E. Buring, and N. Rifai C-reactive protein and other markers of inflammation in the prediction of cardiovascular disease in women N Engl J Med 342 March (12) 2000 836 843
13. J. Danesh, J.G. Wheeler, G.M. Hirschfield, S. Eda, G. Eiriksdottir, and A. Rumley C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease N Engl J Med 350 April (14) 2004 1387 1397
14. S. Kaptoge, E. Di Angelantonio, G. Lowe, M.B. Pepys, S.G. Thompson, and R. Collins C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis Lancet 375 January (9709) 2010 132 140
15. S. Paraskevas, J.D. Huizinga, and B.G. Loos A systematic review and meta-analyses on C-reactive protein in relation to periodontitis J Clin Periodontol 35 April (4) 2008 277 290
16. B.R. Dorn, W.A. Dunn Jr., and A. Progulske-Fox Invasion of human coronary artery cells by periodontal pathogens Infect Immun 67 Novemeber (11) 1999 5792 5798
17. T. Honda, T. Oda, H. Yoshie, and K. Yamazaki Effects of Porphyromonas gingivalis antigens and proinflammatory cytokines on human coronary artery endothelial cells Oral Microbiol Immunol 20 April (2) 2005 82 88
18. K. Tabeta, K. Yamazaki, H. Hotokezaka, H. Yoshie, and K. Hara Elevated humoral immune response to heat shock protein 60 (hsp60) family in periodontitis patients Clin Exp Immunol 120 May (2) 2000 285 293
19. K. Yamazaki, Y. Ohsawa, H. Itoh, K. Ueki, K. Tabeta, and T. Oda T-cell clonality to Porphyromonas gingivalis and human heat shock protein 60 s in patients with atherosclerosis and periodontitis Oral Microbiol Immunol 19 June (3) 2004 160 167
20. K. Yamazaki, Y. Ohsawa, K. Tabeta, H. Ito, K. Ueki, and T. Oda Accumulation of human heat shock protein 60-reactive T cells in the gingival tissues of periodontitis patients Infect Immun 70 May (5) 2002 2492 2501
21. J.D. Beck, P. Eke, G. Heiss, P. Madianos, D. Couper, and D. Lin Periodontal disease and coronary heart disease: a reappraisal of the exposure Circulation 112 July (1) 2005 19 24
22. P.J. Pussinen, K. Nyyssonen, G. Alfthan, R. Salonen, J.A. Laukkanen, and J.T. Salonen Serum antibody levels to Actinobacillus actinomycetemcomitans predict the risk for coronary heart disease Arterioscler Thromb Vasc Biol 25 April (4) 2005 833 838
23. P.J. Pussinen, G. Alfthan, P. Jousilahti, S. Paju, and J. Tuomilehto Systemic exposure to Porphyromonas gingivalis predicts incident stroke Atherosclerosis 193 July (1) 2007 222 228
24. K. Yamazaki, T. Honda, H. Domon, T. Okui, K. Kajita, and R. Amanuma Relationship of periodontal infection to serum antibody levels to periodontopathic bacteria and inflammatory markers in periodontitis patients with coronary heart disease Clin Exp Immunol 149 September (3) 2007 445 452
25. T.J. O'Leary, R.B. Drake, and J.E. Naylor The plaque control record J Periodontol 43 January (1) 1972 38
26. Y. Murayama, A. Nagai, K. Okamura, H. Kurihara, Y. Nomura, S. Kokeguchi, and K. Kato Serum immunoglobulin G antibody to periodontal bacteria Adv Dent Res 2 2 1988 339 345
27. H. Arima, M. Kubo, K. Yonemoto, Y. Doi, T. Ninomiya, and Y. Tanizaki High-sensitivity C-reactive protein and coronary heart disease in a general population of Japanese: the Hisayama study Arterioscler Thromb Vasc Biol 28 July (7) 2008 1385 1391
28. Y. Naito, K. Okuda, and I. Takazoe Immunoglobulin G response to subgingival gram-negative bacteria in human subjects Infect Immun 45 July (1) 1984 47 51
29. P.N. Papapanou, A.M. Neiderud, E. Disick, E. Lalla, G.C. Miller, and G. Dahlen Longitudinal stability of serum immunoglobulin G responses to periodontal bacteria J Clin Periodontol 31 Novemeber (11) 2004 985 990
30. T.J. Sims, R.E. Schifferle, R.W. Ali, N. Skaug, and R.C. Page Immunoglobulin G response of periodontitis patients to Porphyromonas gingivalis capsular carbohydrate and lipopolysaccharide antigens Oral Microbiol Immun 16 August (4) 2001 193 201
31. I.B. Lamster, I. Kaluszhner-Shapira, M. Herrera-Abreu, R. Sinha, and J.T. Grbic Serum IgG antibody response to Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis: implications for periodontal diagnosis J Clin Periodontol 25 June (6) 1998 510 516
32. B.A. Dye, M. Herrera-Abreu, J. Lerche-Sehm, C. Vlachojannis, L. Pikdoken, and B. Pretzl Serum antibodies to periodontal bacteria as diagnostic markers of periodontitis J Periodontol 80 April (4) 2009 634 647
33. B.G. Loos Systemic markers of inflammation in periodontitis J Periodontol 76 Novemeber (11 Suppl.) 2005 2106 2115
34. M.S. Tonetti Periodontitis and risk for atherosclerosis: an update on intervention trials J Clin Periodontol 36 July (Suppl. 10) 2009 15 19
35. K. Yamazaki, T. Honda, T. Oda, K. Ueki-Maruyama, T. Nakajima, and H. Yoshie Effect of periodontal treatment on the C-reactive protein and proinflammatory cytokine levels in Japanese periodontitis patients J Periodontal Res 40 February (1) 2005 53 58
36. T. Nakajima, T. Honda, H. Domon, T. Okui, K. Kajita, and H. Ito Periodontitis-associated up-regulation of systemic inflammatory mediator level may increase the risk of coronary heart disease J Periodontal Res 45 February (1) 2010 116 122
37. B.A. Dye, K. Choudhary, S. Shea, and P.N. Papapanou Serum antibodies to periodontal pathogens and markers of systemic inflammation J Clin Periodontol 32 Decemeber (12) 2005 1189 1199
38. P.J. Pussinen, K. Tuomisto, P. Jousilahti, A.S. Havulinna, J. Sundvall, and V. Salomaa Endotoxemia, immune response to periodontal pathogens, and systemic inflammation associate with incident cardiovascular disease events Arterioscl Throm Vas 27 June (6) 2007 1433 1439
39. T. Maekawa, N. Takahashi, T. Honda, D. Yonezawa, H. Miyashita, and T. Okui Porphyromonas gingivalis antigens and interleukin-6 stimulate the production of monocyte chemoattractant protein-1 via the upregulation of early growth response-1 transcription in human coronary artery endothelial cells J Vasc Res 47 4 2010 346 354
40. C.S. Carlson, S.F. Aldred, P.K. Lee, R.P. Tracy, S.M. Schwartz, and M. Rieder Polymorphisms within the C-reactive protein (CRP) promoter region are associated with plasma CRP levels Am J Hum Genet 77 July (1) 2005 64 77
41. D.T. Miller, R.Y. Zee, J. Suk Danik, P. Kozlowski, D.I. Chasman, and R. Lazarus Association of common CRP gene variants with CRP levels and cardiovascular events Ann Hum Genet 69 Novemeber (Pt. 6) 2005 623 638