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Volumn 180, Issue 6, 2012, Pages 2504-2515

Spontaneous formation of tumorigenic hybrids between breast cancer and multipotent stromal cells is a source of tumor heterogeneity

Author keywords

[No Author keywords available]

Indexed keywords

ANEUPLOIDY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; BREAST CANCER; BREAST CARCINOGENESIS; BREAST CARCINOMA; BREAST METASTASIS; CANCER CELL CULTURE; CANCER GROWTH; CANCER INVASION; CARCINOMA CELL; CELL HETEROGENEITY; CELL MIGRATION; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; HYBRID CELL; IMMUNE DEFICIENCY; IN VITRO STUDY; MESENCHYMAL STROMA CELL; MOUSE; MULTIPOTENT STROMA CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PLOIDY; PRIORITY JOURNAL; RNA SEQUENCE; SINGLE NUCLEOTIDE POLYMORPHISM; STROMA CELL; TUMOR XENOGRAFT;

EID: 84861580867     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2012.02.020     Document Type: Article
Times cited : (82)

References (51)
  • 1
    • 76649128993 scopus 로고    scopus 로고
    • Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype
    • S.Y. Park, M. Gonen, H.J. Kim, F. Michor, K. Polyak Cellular and genetic diversity in the progression of in situ human breast carcinomas to an invasive phenotype J Clin Invest 120 2010 636 644
    • (2010) J Clin Invest , vol.120 , pp. 636-644
    • Park, S.Y.1    Gonen, M.2    Kim, H.J.3    Michor, F.4    Polyak, K.5
  • 3
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • J.P. Thiery Epithelial-mesenchymal transitions in tumour progression Nat Rev Cancer 2 2002 442 454
    • (2002) Nat Rev Cancer , vol.2 , pp. 442-454
    • Thiery, J.P.1
  • 4
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
    • K. Polyak, R.A. Weinberg Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits Nat Rev Cancer 9 2009 265 273
    • (2009) Nat Rev Cancer , vol.9 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 5
    • 0035720007 scopus 로고    scopus 로고
    • Phenotypic and genetic alterations in mammary stroma: Implications for tumour progression
    • S.L. Schor, A.M. Schor Phenotypic and genetic alterations in mammary stroma: implications for tumour progression Breast Cancer Res 3 2001 373 379
    • (2001) Breast Cancer Res , vol.3 , pp. 373-379
    • Schor, S.L.1    Schor, A.M.2
  • 8
    • 0036674501 scopus 로고    scopus 로고
    • Dissemination and growth of cancer cells in metastatic sites
    • A.F. Chambers, A.C. Groom, I.C. MacDonald Dissemination and growth of cancer cells in metastatic sites Nat Rev Cancer 2 2002 563 572
    • (2002) Nat Rev Cancer , vol.2 , pp. 563-572
    • Chambers, A.F.1    Groom, A.C.2    MacDonald, I.C.3
  • 9
    • 33845809125 scopus 로고    scopus 로고
    • Mesenchymal-to-epithelial transition facilitates bladder cancer metastasis: Role of fibroblast growth factor receptor-2
    • C.L. Chaffer, J.P. Brennan, J.L. Slavin, T. Blick, E.W. Thompson, E.D. Williams Mesenchymal-to-epithelial transition facilitates bladder cancer metastasis: role of fibroblast growth factor receptor-2 Cancer Res 66 2006 11271 11278
    • (2006) Cancer Res , vol.66 , pp. 11271-11278
    • Chaffer, C.L.1    Brennan, J.P.2    Slavin, J.L.3    Blick, T.4    Thompson, E.W.5    Williams, E.D.6
  • 11
    • 70349729970 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition and cell cooperativity in metastasis
    • T. Tsuji, S. Ibaragi, G.F. Hu Epithelial-mesenchymal transition and cell cooperativity in metastasis Cancer Res 69 2009 7135 7139
    • (2009) Cancer Res , vol.69 , pp. 7135-7139
    • Tsuji, T.1    Ibaragi, S.2    Hu, G.F.3
  • 12
    • 56849131881 scopus 로고    scopus 로고
    • The cancer cell-leukocyte fusion theory of metastasis
    • J.M. Pawelek, A.K. Chakraborty The cancer cell-leukocyte fusion theory of metastasis Adv Cancer Res 101 2008 397 444
    • (2008) Adv Cancer Res , vol.101 , pp. 397-444
    • Pawelek, J.M.1    Chakraborty, A.K.2
  • 13
    • 0342737671 scopus 로고
    • Uber zellverschmelzung mit qualitativ abnormer chromosomenverteilung als ursache der geschwulstbildung
    • W. Roux, Wilhelm Engelmann Leipzig
    • O. Aichel Uber zellverschmelzung mit qualitativ abnormer chromosomenverteilung als ursache der geschwulstbildung W. Roux, Vortrage und aufsatze uber entvickelungsmechanik der organismen, Chapter XIII 1911 Wilhelm Engelmann Leipzig 92 111
    • (1911) Vortrage und Aufsatze Uber Entvickelungsmechanik der Organismen, Chapter XIII , pp. 92-111
    • Aichel, O.1
  • 14
    • 42549167207 scopus 로고    scopus 로고
    • Fusion of tumour cells with bone marrow-derived cells: A unifying explanation for metastasis
    • J.M. Pawelek, A.K. Chakraborty Fusion of tumour cells with bone marrow-derived cells: a unifying explanation for metastasis Nat Rev Cancer 8 2008 377 386
    • (2008) Nat Rev Cancer , vol.8 , pp. 377-386
    • Pawelek, J.M.1    Chakraborty, A.K.2
  • 15
    • 0014336985 scopus 로고
    • On the "human" nature of highly malignant heterotransplantable tumors of human origin
    • D.M. Goldenberg, H. Gotz On the "human" nature of highly malignant heterotransplantable tumors of human origin Eur J Cancer 4 1968 547 548
    • (1968) Eur J Cancer , vol.4 , pp. 547-548
    • Goldenberg, D.M.1    Gotz, H.2
  • 16
    • 0016588204 scopus 로고
    • Cell hybridization: An explanation for the phenotypic diversity of certain tumours
    • T.F. Warner Cell hybridization: an explanation for the phenotypic diversity of certain tumours Med Hypotheses 1 1975 51 57
    • (1975) Med Hypotheses , vol.1 , pp. 51-57
    • Warner, T.F.1
  • 17
    • 0842320021 scopus 로고    scopus 로고
    • Cell fusion: A hidden enemy?
    • D. Duelli, Y. Lazebnik Cell fusion: a hidden enemy? Cancer Cell 3 2003 445 448
    • (2003) Cancer Cell , vol.3 , pp. 445-448
    • Duelli, D.1    Lazebnik, Y.2
  • 18
    • 72249120354 scopus 로고    scopus 로고
    • Cell fusion as a hidden force in tumor progression
    • X. Lu, Y. Kang Cell fusion as a hidden force in tumor progression Cancer Res 69 2009 8536 8539
    • (2009) Cancer Res , vol.69 , pp. 8536-8539
    • Lu, X.1    Kang, Y.2
  • 19
    • 79951825045 scopus 로고    scopus 로고
    • Fusion between intestinal epithelial cells and macrophages in a cancer context results in nuclear reprogramming
    • A.E. Powell, E.C. Anderson, P.S. Davies, A.D. Silk, C. Pelz, S. Impey, M.H. Wong Fusion between intestinal epithelial cells and macrophages in a cancer context results in nuclear reprogramming Cancer Res 71 2011 1497 1505
    • (2011) Cancer Res , vol.71 , pp. 1497-1505
    • Powell, A.E.1    Anderson, E.C.2    Davies, P.S.3    Silk, A.D.4    Pelz, C.5    Impey, S.6    Wong, M.H.7
  • 21
    • 0029851043 scopus 로고    scopus 로고
    • Brain metastasis model in athymic nude mice using a novel MUC1-secreting human breast-cancer cell line, MA11
    • P.D. Rye, L. Norum, D.R. Olsen, S. Garman-Vik, S. Kaul, O. Fodstad Brain metastasis model in athymic nude mice using a novel MUC1-secreting human breast-cancer cell line, MA11 Int J Cancer 68 1996 682 687
    • (1996) Int J Cancer , vol.68 , pp. 682-687
    • Rye, P.D.1    Norum, L.2    Olsen, D.R.3    Garman-Vik, S.4    Kaul, S.5    Fodstad, O.6
  • 22
    • 77952889970 scopus 로고    scopus 로고
    • Phenotypic characterization of mammosphere-forming cells from the human MA11 breast carcinoma cell line
    • G. Rappa, A. Lorico Phenotypic characterization of mammosphere-forming cells from the human MA11 breast carcinoma cell line Exp Cell Res 316 2010 1576 1586
    • (2010) Exp Cell Res , vol.316 , pp. 1576-1586
    • Rappa, G.1    Lorico, A.2
  • 23
    • 38349060190 scopus 로고    scopus 로고
    • Human multipotent stromal cells undergo sharp transition from division to development in culture
    • B.L. Larson, J. Ylostalo, D.J. Prockop Human multipotent stromal cells undergo sharp transition from division to development in culture Stem Cells 26 2008 193 201
    • (2008) Stem Cells , vol.26 , pp. 193-201
    • Larson, B.L.1    Ylostalo, J.2    Prockop, D.J.3
  • 24
    • 0032899919 scopus 로고    scopus 로고
    • Design of 5′ untranslated sequences in retroviral vectors developed for medical use
    • M. Hildinger, K.L. Abel, W. Ostertag, C. Baum Design of 5′ untranslated sequences in retroviral vectors developed for medical use J Virol 73 1999 4083 4089
    • (1999) J Virol , vol.73 , pp. 4083-4089
    • Hildinger, M.1    Abel, K.L.2    Ostertag, W.3    Baum, C.4
  • 25
  • 26
    • 0032617585 scopus 로고    scopus 로고
    • Cell migration into a wounded area in vitro
    • M.G. Lampugnani Cell migration into a wounded area in vitro Methods Mol Biol 96 1999 177 182
    • (1999) Methods Mol Biol , vol.96 , pp. 177-182
    • Lampugnani, M.G.1
  • 27
    • 0030665969 scopus 로고    scopus 로고
    • Disruption of the murine MRP (multidrug resistance protein) gene leads to increased sensitivity to etoposide (VP-16) and increased levels of glutathione
    • A. Lorico, G. Rappa, R.A. Finch, D. Yang, R.A. Flavell, A.C. Sartorelli Disruption of the murine MRP (multidrug resistance protein) gene leads to increased sensitivity to etoposide (VP-16) and increased levels of glutathione Cancer Res 57 1997 5238 5242
    • (1997) Cancer Res , vol.57 , pp. 5238-5242
    • Lorico, A.1    Rappa, G.2    Finch, R.A.3    Yang, D.4    Flavell, R.A.5    Sartorelli, A.C.6
  • 30
    • 0036456669 scopus 로고    scopus 로고
    • Expansion of human adult stem cells from bone marrow stroma: Conditions that maximize the yields of early progenitors and evaluate their quality
    • I. Sekiya, B.L. Larson, J.R. Smith, R. Pochampally, J.G. Cui, D.J. Prockop Expansion of human adult stem cells from bone marrow stroma: conditions that maximize the yields of early progenitors and evaluate their quality Stem Cells 20 2002 530 541
    • (2002) Stem Cells , vol.20 , pp. 530-541
    • Sekiya, I.1    Larson, B.L.2    Smith, J.R.3    Pochampally, R.4    Cui, J.G.5    Prockop, D.J.6
  • 32
    • 36249021493 scopus 로고    scopus 로고
    • Concise review: Mesenchymal stem/multipotent stromal cells: The state of transdifferentiation and modes of tissue repair-current views
    • D.G. Phinney, D.J. Prockop Concise review: mesenchymal stem/multipotent stromal cells: the state of transdifferentiation and modes of tissue repair-current views Stem Cells 25 2007 2896 2902
    • (2007) Stem Cells , vol.25 , pp. 2896-2902
    • Phinney, D.G.1    Prockop, D.J.2
  • 35
    • 79960896892 scopus 로고    scopus 로고
    • Cell fusion hypothesis of the cancer stem cell
    • X. Lu, Y. Kang Cell fusion hypothesis of the cancer stem cell Adv Exp Med Biol 714 2011 129 140
    • (2011) Adv Exp Med Biol , vol.714 , pp. 129-140
    • Lu, X.1    Kang, Y.2
  • 36
    • 67249120052 scopus 로고    scopus 로고
    • Efficient acquisition of dual metastasis organotropism to bone and lung through stable spontaneous fusion between MDA-MB-231 variants
    • X. Lu, Y. Kang Efficient acquisition of dual metastasis organotropism to bone and lung through stable spontaneous fusion between MDA-MB-231 variants Proc Natl Acad Sci U S A 106 2009 9385 9390
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 9385-9390
    • Lu, X.1    Kang, Y.2
  • 37
  • 38
    • 33748087454 scopus 로고    scopus 로고
    • Spontaneous fusion with, and transformation of mouse stroma by, malignant human breast cancer epithelium
    • B.M. Jacobsen, J.C. Harrell, P. Jedlicka, V.F. Borges, M. Varella-Garcia, K.B. Horwitz Spontaneous fusion with, and transformation of mouse stroma by, malignant human breast cancer epithelium Cancer Res 66 2006 8274 8279
    • (2006) Cancer Res , vol.66 , pp. 8274-8279
    • Jacobsen, B.M.1    Harrell, J.C.2    Jedlicka, P.3    Borges, V.F.4    Varella-Garcia, M.5    Horwitz, K.B.6
  • 41
    • 28044432759 scopus 로고    scopus 로고
    • Tumour-cell fusion as a source of myeloid traits in cancer
    • J.M. Pawelek Tumour-cell fusion as a source of myeloid traits in cancer Lancet Oncol 6 2005 988 993
    • (2005) Lancet Oncol , vol.6 , pp. 988-993
    • Pawelek, J.M.1
  • 42
    • 28044433869 scopus 로고    scopus 로고
    • Cell fusion: New mechanisms of plasticity in cancer?
    • P. Friedl Cell fusion: new mechanisms of plasticity in cancer? Lancet Oncol 6 2005 916 918
    • (2005) Lancet Oncol , vol.6 , pp. 916-918
    • Friedl, P.1
  • 43
    • 35148886434 scopus 로고    scopus 로고
    • Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
    • L. Ma, J. Teruya-Feldstein, R.A. Weinberg Tumour invasion and metastasis initiated by microRNA-10b in breast cancer Nature 449 2007 682 688
    • (2007) Nature , vol.449 , pp. 682-688
    • Ma, L.1    Teruya-Feldstein, J.2    Weinberg, R.A.3
  • 44
    • 76049114936 scopus 로고    scopus 로고
    • Heterogeneity for stem cell-related markers according to tumor subtype and histologic stage in breast cancer
    • S.Y. Park, H.E. Lee, H. Li, M. Shipitsin, R. Gelman, K. Polyak Heterogeneity for stem cell-related markers according to tumor subtype and histologic stage in breast cancer Clin Cancer Res 16 2010 876 887
    • (2010) Clin Cancer Res , vol.16 , pp. 876-887
    • Park, S.Y.1    Lee, H.E.2    Li, H.3    Shipitsin, M.4    Gelman, R.5    Polyak, K.6
  • 48
    • 75449106680 scopus 로고    scopus 로고
    • Stem cell and epithelial-mesenchymal transition markers are frequently overexpressed in circulating tumor cells of metastatic breast cancer patients
    • B. Aktas, M. Tewes, T. Fehm, S. Hauch, R. Kimmig, S. Kasimir-Bauer Stem cell and epithelial-mesenchymal transition markers are frequently overexpressed in circulating tumor cells of metastatic breast cancer patients Breast Cancer Res 11 2009 R46
    • (2009) Breast Cancer Res , vol.11 , pp. 46
    • Aktas, B.1    Tewes, M.2    Fehm, T.3    Hauch, S.4    Kimmig, R.5    Kasimir-Bauer, S.6
  • 51
    • 0033794296 scopus 로고    scopus 로고
    • Flow cytometric analysis of primary tumors and their corresponding metastatic nodes in breast cancer
    • H.S. Kang, Y.K. Youn, S.K. Oh, K.J. Choe, D.Y. Noh Flow cytometric analysis of primary tumors and their corresponding metastatic nodes in breast cancer Breast Cancer Res Treat 63 2000 81 87
    • (2000) Breast Cancer Res Treat , vol.63 , pp. 81-87
    • Kang, H.S.1    Youn, Y.K.2    Oh, S.K.3    Choe, K.J.4    Noh, D.Y.5


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