The JmjC domain-containing histone demethylase KDM3A is a positive regulator of the G 1/S transition in cancer cells via transcriptional regulation of the HOXA1 gene

International Journal of Cancer

Volumn 131, Issue 3, 2012, Pages

  Cho, Hyun Soo ^a   Toyokawa, Gouji ^a,b   Daigo, Yataro ^a,c   Hayami, Shinya ^a   Masuda, Ken ^a   Ikawa, Noriko ^a   Yamane, Yuka ^a   Maejima, Kazuhiro ^a   Tsunoda, Tatsuhiko ^d   Field, Helen I ^e   Kelly, John D ^e,f   Neal, David E ^e   Ponder, Bruce A J ^e   Maehara, Yoshihiko ^b   Nakamura, Yusuke ^a   Hamamoto, Ryuji ^a,e  

^a UNIVERSITY OF TOKYO   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

^d RIKEN   (Japan)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^f ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

epigenetics; HOXA1; human carcinogenesis; KDM3A

Indexed keywords

COMPLEMENTARY DNA; CYCLIN D1; HISTONE DEMETHYLASE; HISTONE DEMETHYLASE KDM3A; HISTONE H3; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HOXA1; UNCLASSIFIED DRUG;

ADULT; AGED; ARTICLE; BILE DUCT CARCINOMA; BLADDER CARCINOMA; CANCER CELL; CANCER CELL CULTURE; CANCER GROWTH; CARCINOGENESIS; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL CYCLE S PHASE; CELL PROLIFERATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DEMETHYLATION; DOWN REGULATION; FEMALE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE OVEREXPRESSION; GENE SILENCING; HOMEOBOX; HOXA1 GENE; HUMAN; HUMAN CELL; HUMAN TISSUE; INHIBITION KINETICS; KDM3A GENE; LUNG NON SMALL CELL CANCER; MALE; MICROARRAY ANALYSIS; OSTEOSARCOMA; PHASE TRANSITION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN DOMAIN; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION;

CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIN D1; G1 PHASE CELL CYCLE CHECKPOINTS; GENE EXPRESSION REGULATION, NEOPLASTIC; HISTONES; HOMEODOMAIN PROTEINS; HUMANS; JUMONJI DOMAIN-CONTAINING HISTONE DEMETHYLASES; LUNG NEOPLASMS; METHYLATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; URINARY BLADDER NEOPLASMS;

EID: 84861574307     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.26501     Document Type: Article

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