GDF-15 promotes angiogenesis through modulating p53/HIF-1α signaling pathway in hypoxic human umbilical vein endothelial cells

Molecular Biology Reports

Volumn 39, Issue 4, 2012, Pages 4017-4022

  Song, Hejian ^a   Yin, Delu ^b   Liu, Zhihua ^a  

^a THE FIRST AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

^b First People's Hospital of Lianyungang City   (China)

Author keywords

Angiogenesis; GDF 15; HIF 1 ; P53

Indexed keywords

GROWTH DIFFERENTIATION FACTOR 15; HYPOXIA INDUCIBLE FACTOR 1ALPHA; NUTLIN 3; PROTEIN MDM2; PROTEIN P53; VASCULOTROPIN; GDF15 PROTEIN, HUMAN; HIF1A PROTEIN, HUMAN; MDM2 PROTEIN, HUMAN;

ANGIOGENESIS; ARTICLE; COMPLEX FORMATION; HUMAN; HUMAN CELL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL; APOPTOSIS; CELL HYPOXIA; CELL NUCLEUS; CYTOLOGY; DRUG EFFECT; METABOLISM; PROTEIN BINDING; UBIQUITINATION;

APOPTOSIS; CELL HYPOXIA; CELL NUCLEUS; GROWTH DIFFERENTIATION FACTOR 15; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; NEOVASCULARIZATION, PHYSIOLOGIC; PROTEIN BINDING; PROTEIN TRANSPORT; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS C-MDM2; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITINATION;

EID: 84861554128     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-011-1182-7     Document Type: Article

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