Dynamics of plasmodium falciparum selection after artemether-lumefantrine treatment in Africa

Journal of Infectious Diseases

Volumn 205, Issue 9, 2012, Pages 1473-1475

  Ferreira, Pedro Eduardo ^a,b   Culleton, Richard ^c  

^a KAROLINSKA INSTITUTE   (Sweden)

^b UNIVERSITY OF ALGARVE   (Portugal)

^c NAGASAKI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ARTEMETHER PLUS BENFLUMETOL;

AFRICA; ANTIMALARIAL DRUG RESISTANCE; DRUG CLEARANCE; DRUG EFFICACY; GENE; GENE FREQUENCY; GENE MUTATION; GENETIC ASSOCIATION; GENETIC SELECTION; HUMAN; LETTER; MALARIA FALCIPARUM; MDR1 GENE; NONHUMAN; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; REINFECTION; TREATMENT DURATION;

ANTIMALARIALS; DRUG RESISTANCE; FEMALE; HUMANS; MALARIA, FALCIPARUM; MALE; PLASMODIUM FALCIPARUM; POLYMORPHISM, GENETIC;

EID: 84861549354     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jis227     Document Type: Letter

References (4)

1. Baliraine FN, Rosenthal PJ. Prolonged selection of pfmdr1 polymorphisms after treatment of falciparum malaria with artemetherlumefantrine in Uganda. J Infect Dis 2011; 204:1120-4.
2. Sisowath C, Strömberg J, Martensson A, et al. In vivo selection of Plasmodium falciparum pfmdr1 86N coding alleles by artemetherlumefantrine (Coartem). J Infect Dis 2005; 191:1014-17.
3. Sisowath C, Ferreira PE, Bustamante LY, et al. The role of pfmdr1 in Plasmodium falciparum tolerance to artemether-lumefantrine in Africa. Trop Med Int Health 2007; 12:736-42.
4. Ngasala BE, Malmberg M, Carlsson AM, et al. Efficacy and effectiveness of artemetherlumefantrine after initial and repeated treatment in children,5 years of age with acute uncomplicated Plasmodium falciparum malaria in rural Tanzania: a randomized trial. Clin Infect Dis 2011; 52:873-82.