Impact of heart failure and changes to volume status on liver stiffness: Non-invasive assessment using transient elastography

European Journal of Heart Failure

Volumn 14, Issue 6, 2012, Pages 621-627

  Hopper, Ingrid ^a,b   Kemp, William ^a   Porapakkham, Pornwalee ^a,b,c   Sata, Yusuke ^a,b   Condon, Eilis ^a   Skiba, Marina ^a,b   Farber, Lauren ^a   Porapakkham, Pramote ^a,b,c   Williams, Trevor J ^a,b   Menahem, Solomon ^a   Roberts, Stuart ^a   Krum, Henry ^a,b  

^a Department of Clinical Pharmacology and Therapeutics ^*  (Australia)

^b MONASH UNIVERSITY   (Australia)

^c MINISTRY OF PUBLIC HEALTH   (Thailand)

Author keywords

Cardiac hepatopathy; Diuresis; Haemodialysis; Heart failure; Transient elastography

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ALDOSTERONE ANTAGONIST; ALKALINE PHOSPHATASE; AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BILIRUBIN; CHOLESTEROL; DIURETIC AGENT; GAMMA GLUTAMYLTRANSFERASE; GLUCOSE; HEMOGLOBIN; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ACUTE HEART FAILURE; ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALBUMIN BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ARTICLE; BILIRUBIN BLOOD LEVEL; CARDIAC PATIENT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DIASTOLIC BLOOD PRESSURE; DISEASE DURATION; DIURESIS; ELASTOGRAPHY; FEMALE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; GLOMERULUS FILTRATION RATE; GLUCOSE BLOOD LEVEL; HEART EJECTION FRACTION; HEART FAILURE; HEART RATE; HEMODIALYSIS; HEMODIALYSIS PATIENT; HEMOGLOBIN BLOOD LEVEL; HUMAN; LEFT SIDED HEART FAILURE; LIVER STIFFNES; LIVER WEIGHT; MAJOR CLINICAL STUDY; MALE; MECHANICAL PROBE; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTHROMBIN TIME; RIGHT SIDED HEART FAILURE; RIGIDITY; SYSTOLIC BLOOD PRESSURE; THROMBOCYTE COUNT; TRANSIENT ELASTOGRAPHY; TREATMENT RESPONSE; TRIACYLGLYCEROL BLOOD LEVEL; ULTRAFILTRATION; WAIST CIRCUMFERENCE;

AGED; CHI-SQUARE DISTRIBUTION; CROSS-SECTIONAL STUDIES; DIURESIS; ELASTICITY IMAGING TECHNIQUES; FEMALE; HEART FAILURE; HEMODYNAMICS; HUMANS; LIVER; LIVER CIRRHOSIS; LIVER DISEASES; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; STATISTICS AS TOPIC; STATISTICS, NONPARAMETRIC; STROKE VOLUME; VENTRICULAR FUNCTION, LEFT;

EID: 84861547311     PISSN: 13889842     EISSN: 18790844     Source Type: Journal    
DOI: 10.1093/eurjhf/hfs044     Document Type: Article

References (24)

1. Kiernan F. The anatomy and physiology of the liver. Philos Trans R Soc B: Biol Sci 1833;123:711-770.
2. Sherlock S. The liver in heart failure: relation of anatomical, functional, and circulatory changes. Br Heart J 1951;13:273-293.
3. Myers J, Hickam J. An estimation of hepatic blood flow and splanchnic oxygen consumption in heart failure. J Clin Invest 1948;27:620-627.
4. Richman S, Delman A, Grob D. Alterations in indices of liver funtion in congestive heart failure with particular reference to serum enzymes. Am J Med 1961;30: 211-225.
5. Kubo SH, Walter BA, John DH, Clark M, Cody RJ. Liver function abnormalities in chronic heart failure. Influence of systemic hemodynamics. Arch Intern Med 1987; 147:1227-1230.
6. Gelow JM, Desai AS, Hochberg CP, Glickman JN, Givertz MM, Fang JC. Clinical predictors of hepatic fibrosis in cardiac failure. Circ Heart Fail 2003;3:59-64.
7. Myers RP, Cerini R, Sayegh R, Moreau R, Degott C, Lebrec D, Lee SS. Cardiac hepatopathy: clinical, hemodynamic, and histologic characteristics and correlations. Hepatology 2003;37:393-400.
8. Martinez SM, Crespo G, Navasa M, Forns X. Noninvasive assessment of liver fibrosis. Hepatology 2011;53:325-335.
9. Castera L, Forns X, Alberti A. Non-invasive evaluation of liver fibrosis using transient elastography. J Hepatol 2008;48:835-847.
10. Castera L, Pinzani M. Non-invasive assessment of liver fibrosis: are we ready? Lancet 2010;375:1419-1420.
11. European Association for the Study of the Liver. EASL Clinical Practice Guidelines: management of hepatitis C virus infection. J Hepatol 2011;55:245-264.
12. Coco B, Oliveri F, Maina AM, Ciccorossi P, Sacco R, Colombatto P, Bonino F, Brunetto MR. Transient elastography: a new surrogate marker of liver fibrosis influenced by major changes of transaminases. J Viral Hepat 2007;14:360-36.
13. Arena U, Vizzutti F, Corti G, Ambu S, Stasi C, Bresci S, Moscarella S, Boddi V, Petrarca A, Laffi G, Marra F, Pinzani M. Acute viral hepatitis increases liver stiffness values measured by transient elastography. Hepatology 2008;47:380-384.
14. Millonig G, Reimann FM, Friedrich S, Fonouni H, Mehrabi A, Buchler MW, Seitz HK, Mueller S. Extrahepatic cholestasis increases liver stiffness (FibroScan) irrespective of fibrosis. Hepatology 2008;48:1718-1723.
15. Millonig G, Friedrich S, Adolf S, Fonouni H, Golriz M, Mehrabi A, Stiefel P, Poschl G, Buchler MW, Seitz HK, Mueller S. Liver stiffness is directly influenced by central venous pressure. J Hepatol 2010;52:206-210.
16. Frulio N, Laumonier H, Balabaud C, Trillaud H, Bioulac-Sage P. Hepatic congestion plays a role in liver stiffness. Hepatology 2009;50:1674-1675.
17. Lebray P, Varnous S, Charlotte F, Varaut A, Poynard T, Ratziu V. Liver stiffness is an unreliable marker of liver fibrosis in patients with cardiac insufficiency. Hepatology 2008;48:2089.
18. Lau GT, Tan HC, Kritharides L. Type of liver dysfunction in heart failure and its relation to the severity of tricuspid regurgitation. Am J Cardiol 2002;90: 1405-1409.
19. Colli A, Pozzoni P, Berzuini A, Gerosa A, Canovi C, Molteni EE, Barbarini M, Bonino F, Prati D. Decompensated chronic heart failure: increased liver stiffness measured by means of transient elastography. Radiology 2010;257:872-878.
20. Dechêne A, Sowa J, Gieseler R, Jochum C, Bechmann L, Fouly A, Schlattjan M, Saner F, Baba H, Paul A, Dries V, Odenthal M, Gerken G, Friedman S, Canbay A. Acute liver failure is associated with elevated liver stiffness and hepatic stellate cell activation. Hepatology 2010;52:1008-1016.
21. Lindvig K, Mossner BK, Pedersen C, Lillevang ST, Christensen PB. Liver stiffness and 30-day mortality in a cohort of patients admitted to hospital. Eur J Clin Invest 2012;42:146-152.
22. Koch A, Horn A, Duckers H, Yagmur E, Sanson E, Bruensing J, Buendgens L, Voigt S, Trautwein C, Tacke F. Increased liver stiffness denotes hepatic dysfunction and mortality risk in critically ill non-cirrhotic patients at a medical ICU. Crit Care 2011;15:R266.
23. Castera L, Foucher J, Bernard P-H, Carvalho F, Allaix D, Merrouche W, Couzigou P, de Ledinghen V. Pitfalls of liver stiffness measurement: a 5-year prospective study of 13,369 examinations. Hepatology 2010;51:828-835.
24. Roulot D, Czernichow S, Le Clesiau H, Costes J-L, Vergnaud A-C, Beaugrand M. Liver stiffness values in apparently healthy subjects: influence of gender and metabolic syndrome. J Hepatol 2008;48:606-613.