Pilot study of deep brain stimulation in refractory obsessive-compulsive disorder ethnic Chinese patients

Psychiatry and Clinical Neurosciences

Volumn 66, Issue 4, 2012, Pages 303-312

  Tsai, Hsin Chi ^a,b   Chang, Chun Hung ^c,d   Pan, Jiann I ^a   Hsieh, Hung Jen ^b   Tsai, Sheng Tzung ^b   Hung, Hsiang Yi ^b   Chen, Shin Yuan ^a,b  

^a TZU CHI UNIVERSITY   (Taiwan)

^b BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

^c China Medical University and Hospital   (China)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

deep brain stimulation; refractory obsessive compulsive disorder; treatment outcome

Indexed keywords

AMFEBUTAMONE; CLONAZEPAM; CLOZAPINE; FLUOXETINE; LAMOTRIGINE; LORAZEPAM; PAROXETINE; PROPRANOLOL; QUETIAPINE; SERTRALINE; TRIAZOLAM; VALPROIC ACID; VENLAFAXINE; ZOTEPINE;

ADULT; ALLERGIC REACTION; ARTICLE; BRAIN DEPTH STIMULATION; CASE REPORT; CHINESE; CORPUS STRIATUM; DEPRESSION; DISEASE SEVERITY; FOLLOW UP; GLOBAL ASSESSMENT OF FUNCTION SCALE; HAMILTON SCALE; HUMAN; HYPOMANIA; MALE; OBSESSIVE COMPULSIVE DISORDER; PILOT STUDY; RATING SCALE; REFRACTORY OBSESSIVE COMPULSIVE DISORDER; TAIWAN; VERTIGO;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; BASAL GANGLIA; CASE-CONTROL STUDIES; DEEP BRAIN STIMULATION; ELECTRODES, IMPLANTED; FLUORODEOXYGLUCOSE F18; FUNCTIONAL NEUROIMAGING; HUMANS; INTERNAL CAPSULE; MALE; OBSESSIVE-COMPULSIVE DISORDER; PILOT PROJECTS; POSITRON-EMISSION TOMOGRAPHY; PSYCHIATRIC STATUS RATING SCALES; RADIOPHARMACEUTICALS; TAIWAN;

EID: 84861538331     PISSN: 13231316     EISSN: 14401819     Source Type: Journal    
DOI: 10.1111/j.1440-1819.2012.02352.x     Document Type: Article

References (25)

1. Murray CJ, Lopez AD,. Global mortality, disability, and the contribution of risk factors: Global Burden of Disease Study. Lancet 1997; 349: 1436-1442.
2. Meyerson BA,. Neurosurgical treatment of mental disorders: Introduction and indications. In:, Gildenberg PL, Tasker RR, (eds). Textbook of Stereotactic and Functional Neurosurgery. McGraw Hill, New York, 1999; 1953-1963.
3. Benabid AL,. What the future holds for deep brain stimulation. Expert Rev. Med. Devices 2007; 4: 895-903.
4. Nuttin B, Gybels J, Cosyns P, et al,. Deep brain stimulation for psychiatric disorders. Neurosurg. Clin. N. Am. 2003; 14: xv-xvi.
5. Nuttin B, Cosyns P, Demeulemeester H, Gybels J, Meyerson B,. Electrical stimulation in anterior limbs of internal capsules in patients with obsessive-compulsive disorder. Lancet 1999; 354: 1526.
6. Anderson D, Ahmed A,. Treatment of patients with intractable obsessive compulsive disorder with anterior capsular stimulation. J. Neurosurg. 2003; 98: 1104-1108.
7. Aouizerate B, Cuny E, Martin-Guehl C, et al,. Deep brain stimulation of the ventral caudate nucleus in the treatment of obsessive-compulsive disorder and major depression. J. Neurosurg. 2004; 101: 682-686.
8. Abelson JL, Curtis GC, Sagher O, et al,. Deep brain stimulation for refractory obsessive-compulsive disorder. Biol. Psychiatry 2005; 57: 510-516.
9. Greenberg BD, Malone DA, Friehs GM, et al,. Three-year outcomes in deep brain stimulation for highly resistant obsessive-compulsive disorder. Neuropsychopharmacology 2006; 31: 2384-2393.
10. Goodman WK, Foote KD, Greenberg BD, et al,. Deep brain stimulation for intractable obsessive compulsive disorder: Pilot study using a blinded, staggered-onset design. Biol. Psychiatry 2010; 67: 535-542. Epub 2010 Feb 8.
11. Blond S, Caparros-Lefebvre D, Parker F, et al,. Control of tremor and involuntary movement disorders by chronic stereotactic stimulation of the ventral intermediate thalamic nucleus. J. Neurosurg. 1992; 77: 62-68.
12. Dougherty DD, Baer L, Cosgrove GR, et al,. Prospective long-term follow-up of 44 patients who received cingulotomy for treatment-refractory obsessive-compulsive disorder. Am. J. Psychiatry 2002; 159: 269-275.
13. Tang HS, Huang CC, Chen KY, et al,. Reliability and validity of the Chinese version of the Yale-Brown Obsessive Compulsive Scale (Y-BOCS). Taiwan. J. Psychiatry 2006; 20: 279-288.
14. Hamilton M,. Development of a rating scale for primary depressive illness. Br. J. Soc. Clin. Psychol. 1967; 6: 278-296.
15. Tai HC, Chen SY, Tsai ST, et al,. Hypomania following bilateral ventral capsule stimulation in a patient with refractory obsessive-compulsive disorder. Biol. Psychiatry 2010; 68: e7-e8.
16. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 4th edn. text rev.: DSMIV-TR. American Psychiatric Association, Washington, DC, 2000.
17. Brett M,. The MNI brain and the Talairach atlas. Website of the Cognition and Brain Sciences Unit of the Medical Research Council. 2006 March 6. [Cited 5 September 2011.] Available from URL: (last accessed 15 April 2012).
18. Calder AJ, Lawrence AD, Young AW,. Neuropsychology of fear and loathing. Nat. Rev. Neurosci. 2001; 2: 352-363.
19. Malone DA Jr,. Use of deep brain stimulation in treatment-resistant depression. Cleve. Clin. J. Med. 2010; 77: S77-S80.
20. Shapira NA, Okun MS, Wint D, et al,. Panic and fear induced by deep brain stimulation. J. Neurol. Neurosurg. Psychiatry 2006; 77: 410-412.
21. Lipsman N, Neimat JS, Lozano AM,. Deep brain stimulation for treatment-refractory OCD: the search for valid target. Neurosurgery 2007; 61: 1-11. discussion 11-3. Review.
22. Mallet L, Polosan M, Jaafari N, et al,. Subthalamic nucleus stimulation in severe obsessive-compulsive disorder. N. Engl. J. Med. 2008; 359: 2121-2134.
23. Greenberg BD, Gabriels LA, Malone DA Jr, et al,. Deep brain stimulation of the ventral internal capsule/ventral striatum for obsessive-compulsive disorder: worldwide experience. Mol. Psychiatry 2010; 15: 64-79. Epub 2008 May 20.
24. Tye SJ, Frye MA, Lee KH,. Disrupting disordered neurocircuitry: treating refractory psychiatric illness with neuromodulation. Mayo Clin. Proc. 2009; 84: 522-532.
25. Krack P, Hariz MI, Baunez C, Guridi J, Obeso JA,. Deep brain stimulation: from neurology to psychiatry? Trends Neurosci. 2010; 33: 474-484.