Molecular binding of self-assembling peptide EAK16-II with anticancer agent EPT and its implication in cancer cell inhibition

Journal of Controlled Release

Volumn 160, Issue 1, 2012, Pages 33-40

  Lu, Sheng ^a   Wang, Hui ^a   Sheng, Yuebiao ^a   Liu, Mingyao ^b   Chen, P ^a  

^a UNIVERSITY OF WATERLOO   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Drug delivery; Drug loading capacity; Fluorescence; In vitro test; Inner filter effect; Self assembling peptide

Indexed keywords

ANTI-CANCER AGENTS; ANTICANCER DRUG; CANCER CELLS; CHARACTERIZATION METHODS; CONTROLLED RELEASE; CORRECTION METHOD; DELIVERY TECHNIQUES; DEVELOPED MODEL; DRUG LOADING CAPACITY; ELLIPTICINE; EXPERIMENTAL DATA; FACILE METHOD; FLUORESCENCE CHARACTERISTICS; IN-SITU; IN-VITRO; IN-VITRO TESTS; INNER FILTER EFFECTS; LOADING CAPACITIES; MOLECULAR BINDING; MOLECULAR STATE; PEPTIDE COMPLEX; PROTONATED; SELF-ASSEMBLING PEPTIDES; THERAPEUTIC EFFECTS;

CELLS; CRYSTALLINE MATERIALS; CYTOTOXICITY; DRUG DELIVERY; DRUG INTERACTIONS; FLUORESCENCE; PEPTIDES; PROTONATION;

LOADING;

ELLIPTICINE; GLUTAMYLALANYLLYSINE; PEPTIDE; TRIPEPTIDE; UNCLASSIFIED DRUG;

ARTICLE; ATOMIC FORCE MICROSCOPY; CANCER CELL; CANCER INHIBITION; CELL VIABILITY; COMPLEX FORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOTOXICITY; DRUG PROTEIN BINDING; ENCAPSULATION; FLUORESCENCE SPECTROSCOPY; HUMAN; HUMAN CELL; MOLECULAR MODEL; PH; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTON TRANSPORT; THEORETICAL MODEL; ULTRAVIOLET RADIATION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; CRYSTALLIZATION; DRUG CARRIERS; DRUG COMPOUNDING; ELLIPTICINES; HUMANS; HYDROGEN-ION CONCENTRATION; MICROSCOPY, ATOMIC FORCE; MODELS, CHEMICAL; MOLECULAR STRUCTURE; NANOPARTICLES; OLIGOPEPTIDES; STATIC ELECTRICITY; SURFACE PROPERTIES;

EID: 84861526041     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.03.009     Document Type: Article

References (34)

1. T.C. Holmes, S. de Lacalle, X. Su, G. Liu, A. Rich, and S. Zhang Extensive neurite outgrowth and active synapse formation on self-assembling peptide scaffolds Proc. Natl. Acad. Sci. 97 2000 6728 6733
2. E.F. Banwell, E.S. Abelardo, D.J. Adams, M.A. Birchall, A. Corrigan, A.M. Donald, M. Kirkland, L.C. Serpell, M.F. Butler, and D.N. Woolfson Rational design and application of responsive [alpha]-helical peptide hydrogels Nat. Mater. 8 2009 596 600
3. R.N. Shah, N.A. Shah, M.M. Del Rosario Lim, C. Hsieh, G. Nuber, and S.I. Stupp Supramolecular design of self-assembling nanofibers for cartilage regeneration Proc. Natl. Acad. Sci. 107 2010 3293 3298
4. P.C.H. Hsieh, M.E. Davis, J. Gannon, C. MacGillivray, and R.T. Lee Controlled delivery of PDGF-BB for myocardial protection using injectable self-assembling peptide nanofibers J. Clin. Invest. 116 2006 237 248
5. O.H. Aina, T.C. Sroka, M.L. Chen, and K.S. Lam Therapeutic cancer targeting peptides Biopolymers 66 2002 184 199
6. J.J. Schwartz, and S.G. Zhang Peptide-mediated cellular delivery Curr. Opin. Mol. Ther. 2 2000 162 167
7. J. Hawiger Noninvasive intracellular delivery of functional peptides and proteins Curr. Opin. Chem. Biol. 3 1999 89 94
8. C.B. Carlson, P. Mowery, R.M. Owen, E.C. Dykhuizen, and L.L. Kiessling Selective tumor cell targeting using low-affinity, multivalent interactions ACS Chem. Biol. 2 2007 119 127
9. F.X. Gu, R. Karnik, A.Z. Wang, F. Alexis, E. Levy-Nissenbaum, S. Hong, R.S. Langer, and O.C. Farokhzad Targeted nanoparticles for cancer therapy Nano Today 2 2007 14 21
10. P. Lundberg, and U. Langel A brief introduction to cell-penetrating peptides J. Mol. Recognit. 16 2003 227 233
11. D. Derossi, G. Chassaing, and A. Prochiantz Trojan peptides: the penetratin system for intracellular delivery Trends Cell Biol. 8 1998 84 87
12. M. Lindgren, M. Hallbrink, A. Prochiantz, and U. Langel Cell-penetrating peptides Trends Pharmacol. Sci. 21 2000 99 103
13. S. Zhang, T. Holmes, C. Lockshin, and A. Rich Spontaneous assembly of a self-complementary oligopeptide to form a stable macroscopic membrane Proc. Natl. Acad. Sci. U. S. A. 90 1993 3334 3338
14. S. Zhang, C. Lockshin, R. Cook, and A. Rich Unusually stable beta -sheet formation in an ionic self-complementary oligopeptide Biopolymers 34 1994 663 672
15. S. Zhang, T.C. Holmes, C.M. DiPersio, R.O. Hynes, X. Su, and A. Rich Self-complementary oligopeptide matrices support mammalian cell attachment Biomaterials 16 1995 1385 1393
16. S. Zhang Emerging biological materials through molecular self-assembly Biotechnol. Adv. 20 2002 321 339
17. C. Keyes-Baig, J. Duhamel, S.-Y. Fung, J. Bezaire, and P. Chen Self-assembling peptide as a potential carrier of hydrophobic compounds J. Am. Chem. Soc. 126 2004 7522 7532
18. S.Y. Fung, H. Yang, and P. Chen Formation of colloidal suspension of hydrophobic compounds with an amphiphilic self-assembling peptide Colloids Surf. B Biointerfaces 55 2007 200 211
19. J. Liu, Y. Xiao, and C. Allen Polymer-drug compatibility: a guide to the development of delivery systems for the anticancer agent, ellipticine J. Pharm. Sci. 93 2004 132 143
20. S.Y. Fung, H. Yang, P.T. Bhola, P. Sadatmousavi, E. Muzar, M. Liu, and P. Chen Self-assembling peptide as a potential carrier for hydrophobic anticancer drug ellipticine: complexation, release and in vitro delivery Adv. Funct. Mater. 19 2009 74 83
21. S.Y. Fung, C. Keyes, J. Duhamel, and P. Chen Concentration effect on the aggregation of a self-assembling oligopeptide Biophys. J. 85 2003 537 548
22. Y. Hong, R.L. Legge, S. Zhang, and P. Chen Effect of amino acid sequence and pH on nanofiber formation of self-assembling peptides EAK16-II and EAK16-IV Biomacromolecules 4 2003 1433 1442
23. S.Y. Fung, J. Duhamel, and P. Chen Solvent effect on the photophysical properties of the anticancer agent ellipticine J. Phys. Chem. A 110 2006 11446 11454
24. Q. Gu, and J.E. Kenny Improvement of inner filter effect correction based on determination of effective geometric parameters using a conventional fluorimeter Anal. Chem. (Washington, DC, United States) 81 2009 420 426
25. E.D. Matayoshi, G.T. Wang, G.A. Krafft, and J. Erickson Novel fluorogenic substrates for assaying retroviral proteases by resonance energy transfer Science 247 1990 954 958
26. C. Helene, F. Brun, and M. Yaniv Fluorescence study of interactions between valyl-t RNA synthetase and valine-specific tRNA's from Escherichia coli Biochem. Biophys. Res. Commun. 37 1969 393 398
27. N.C. Price, and G.K. Radda The binding of NAD + to rabbit muscle glyceraldehyde-3-phosphate dehydrogenase studied by protein fluorescence quenching Biochim. Biophys. Acta (BBA) - Enzymol. 235 1971 27 31
28. G. Weill, and M. Calvin Optical properties of chromophore-macromolecule complexes: absorption and fluorescence of acridine dyes bound to polyphosphates and DNA Biopolymers 1 1963 401 417
29. C.A. Parker, and W.J. Barnes Some experiments with spectrofluorimeters and filter fluorimeters Analyst 82 1957 606 618
30. C.A. Parker Photoluminescence of Solutions. With Applications to Photochemistry and Analytical Chemistry 1968 Elsevier Pub. Co. Amsterdam, New York etc.
31. K. Greish Enhanced permeability and retention of macromolecular drugs in solid tumors: a royal gate for targeted anticancer nanomedicines J. Drug Target. 15 2007 457 464
32. H. Maeda, T. Sawa, and T. Konno Mechanism of tumor-targeted delivery of macromolecular drugs, including the EPR effect in solid tumor and clinical overview of the prototype polymeric drug SMANCS J. Control. Release 74 2001 47 61
33. I. Brigger, C. Dubernet, and P. Couvreur Nanoparticles in cancer therapy and diagnosis Adv. Drug Deliv. Rev. 54 2002 631 651
34. S.Y. Fung, H. Yang, and P. Chen Sequence effect of self-assembling peptides on the complexation and in vitro delivery of the hydrophobic anticancer drug ellipticine PLoS One 3 2008 e1956