Gamma-secretase inhibitor enhances the cytotoxic effect of bortezomib in multiple myeloma

Cellular Oncology

Volumn 34, Issue 6, 2011, Pages 545-551

  Chen, Feng ^a,b   Pisklakova, Alexandra ^a   Li, Ming ^a   Baz, Rachid ^a   Sullivan, Daniel M ^a   Nefedova, Yulia ^a  

^a H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^b SHANDONG UNIVERSITY   (China)

Author keywords

Bortezomib; Gamma secretase inhibitor; Multiple myeloma; Notch inhibitor

Indexed keywords

BORTEZOMIB; CASPASE 3; GAMMA SECRETASE INHIBITOR; GSI IX; GSI XII; NOTCH RECEPTOR; PROTEASOME; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; BORONIC ACID DERIVATIVE; PYRAZINE DERIVATIVE; SECRETASE;

APOPTOSIS; ARTICLE; BONE MARROW; CYTOTOXICITY; DRUG POTENTIATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; MULTIPLE MYELOMA; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WESTERN BLOTTING; DRUG ANTAGONISM; DRUG EFFECT; FLOW CYTOMETRY; GENETICS; METABOLISM; REAL TIME POLYMERASE CHAIN REACTION; TUMOR CELL LINE;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANTINEOPLASTIC AGENTS; APOPTOSIS; BLOTTING, WESTERN; BORONIC ACIDS; CELL LINE, TUMOR; FLOW CYTOMETRY; HUMANS; MULTIPLE MYELOMA; PYRAZINES; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84861506495     PISSN: 22113428     EISSN: 22113436     Source Type: Journal    
DOI: 10.1007/s13402-011-0060-6     Document Type: Article

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