Silencing suppressor activity of a begomovirus DNA β encoded protein and its effect on heterologous helper virus replication

Virus Research

Volumn 167, Issue 1, 2012, Pages 97-101

  Eini, Omid ^a,b   Dogra, Satish C ^c   Dry, Ian B ^d   Randles, John W ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b UNIVERSITY OF ZANJAN   (Iran)

^c FLINDERS UNIVERSITY   (Australia)

^d CSIRO   (Australia)

Author keywords

Geminivirus; Gene silencing; Satellite DNA; Suppressor

Indexed keywords

AMINO ACID; BETAC1 PROTEIN; DNA BETA SATELLITE; GREEN FLUORESCENT PROTEIN; MICRORNA; SATELLITE DNA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; VIRUS PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; BEGOMOVIRUS; COTTON LEAF CURL MULTAN VIRUS; GENE REPRESSION; HELPER VIRUS; INOCULATION; MIXED INFECTION; NONHUMAN; PLANT DEVELOPMENT; POSTTRANSCRIPTIONAL GENE SILENCING; PRIORITY JOURNAL; TOBACCO; TOMATO LEAF CURL VIRUS; VIRAL PLANT DISEASE; VIRUS; VIRUS REPLICATION;

BEGOMOVIRUS; DNA, VIRAL; HELPER VIRUSES; PLANT DISEASES; RNA INTERFERENCE; SATELLITE VIRUSES; TOBACCO; VIRAL PROTEINS; VIRUS REPLICATION;

BEGOMOVIRUS; COTTON LEAF CURL MULTAN VIRUS; GEMINIVIRIDAE; NICOTIANA OBTUSIFOLIA; TOMATO LEAF CURL VIRUS;

EID: 84861482964     PISSN: 01681702     EISSN: 18727492     Source Type: Journal    
DOI: 10.1016/j.virusres.2012.03.012     Document Type: Article

References (26)

1. Akbergenov R., Si-Ammour A., Blevins T., Amin I., Kutter C., Vanderschuren H., Zhang P., Gruissem W., Meins F., Hohn T., Pooggin M.M. Molecular characterization of geminivirus-derived small RNAs in different plant species. Nucleic Acids Research 2006, 34:462-471.
2. Amin I., Hussain K., Akbergenov R., Yadav J.S., Qazi J., Mansoor S., Hohn T., Fauquet C.M., Briddon R.W. Suppressors of RNA silencing encoded by the components of the cotton leaf curl begomovirus-betasatellite complex. Molecular Plant-Microbe Interactions 2011, 24:973-983.
3. Bisaro D.M. Silencing suppression by geminivirus proteins. Virology 2006, 344:158-168.
4. Briddon R.W., Mansoor S., Bedford I.D., Pinner M.S., Saunders K., Stanley J., Zafar Y., Malik K.A., Markham P.G. Identification of DNA components required for induction of cotton leaf curl disease. Virology 2001, 285:234-243.
5. Brigneti G., Voinnet O., Li W., Ji L., Ding S., Baulcombe D.C. Viral pathogenicity determinants are suppressors of transgene silencing in Nicotiana benthamiana. EMBO Journal 1998, 17:6739-6746.
6. Chellappan P., Vanitharani R., Fauquet C.M. Short interfering RNA accumulation correlates with host recovery in DNA virus-infected hosts, and gene silencing targets specific viral sequences. Journal of Virology 2004, 78:7465-7477.
7. Cui X., Li G., Wang D., Hu D., Zhou X. A begomovirus DNAbeta-encoded protein binds DNA, functions as a suppressor of RNA silencing, and targets the cell nucleus. Journal of Virology 2005, 79:10764-10775.
8. Cuiping G., Zhou X. Phloem specific promoter from a satellite associated with a DNA virus. Virus Research 2005, 115:150-157.
9. Ding S.-W., Voinnet O. Antiviral immunity directed by small RNAs. Cell 2007, 130:413-426.
10. Dry I.B., Rigden J.E., Krake L.R., Mullineaux P.M., Rezaian M.A. Nucleotide sequence and genome organization of tomato leaf curl geminivirus. Journal of General Virology 1993, 74:147-151.
11. Eini O., Behjatnia S.A.A., Dogra S., Dry I.B., Randles J.W., Rezaian M.A. Identification of sequence elements regulating promoter activity and replication of a monopartite begomovirus-associated DNA β satellite. Journal of General Virology 2009, 90:253-260.
12. Eini O., Dogra S., Selth L.A., Dry I.B., Randles J.W., Rezaian M.A. Interaction with a host ubiquitin-conjugating enzyme is required for the pathogenicity of a geminiviral DNA β satellite. Molecular Plant-Microbe Interactions 2009, 22:737-746.
13. Fagoaga C., Pensabene-Bellavia G., Moreno P., Navarro L., Flores R., PeñA.L. Ectopic expression of the p23 silencing suppressor of Citrus tristeza virus differentially modifies viral accumulation and tropism in two transgenic woody hosts. Molecular Plant Pathology 2011, 12:898-910.
14. Gopal P., Pravin Kumar P., Sinilal B., Jose J., Kasin Yadunandam A., Usha R. Differential roles of C4 and βC1 in mediating suppression of post-transcriptional gene silencing: evidence for transactivation by the C2 of Bhendi yellow vein mosaic virus, a monopartite begomovirus. Virus Research 2007, 123:9-18.
15. Guo H.S., Ding S.W. A viral protein inhibits the long range signaling activity of the gene silencing signal. EMBO Journal 2002, 21:398-407.
16. Hannon G.J. RNA interference. Nature 2002, 418:244-251.
17. Kon T., Sharma P., Ikegami M. Suppressor of RNA silencing encoded by the monopartite tomato leaf curl Java begomovirus. Archives of Virology 2007, 152:1273-1282.
18. Lakatos L., Csorba T., Pantaleo V., Chapman E.J., Carrington J.C., Liu Y.-P., Dolja V.V., Calvino L.F., López-Moya J.J., Burgyán J. Small RNA binding is a common strategy to suppress RNA silencing by several viral suppressors. EMBO Journal 2006, 25:2768-2780.
19. Llave C., Kasschau K.D., Carrington J.C. Virus-encoded suppressor of posttranscriptional gene silencing targets a maintenance step in the silencing pathway. Proceedings of the National Academy of Sciences of the United States of America 2000, 97:13401-13406.
20. Meister G., Tuschl T. Mechanisms of gene silencing by double-stranded RNA. Nature 2004, 431:343-349.
21. Palauqui J.-C., Elmayan T., Pollien J.-M., Vaucheret H. Systemic acquired silencing: transgene-specific post-transcriptional silencing is transmitted by grafting from silenced stocks to non-silenced scions. EMBO Journal 1997, 16:4738-4745.
22. Qazi J., Amin I., Mansoor S., Iqbal M.J., Briddon R.W. Contribution of the satellite encoded gene βC1 to cotton leaf curl disease symptoms. Virus Research 2007, 128:135-139.
23. Roth B.M., Gail J.P., Vicki B.V. Plant viral suppressors of RNA silencing. Virus Research 2004, 102:97-108.
24. Saeed M., Behjatnia S.A.A., Shahid M., Yusuf Z., Shahida H., Rezaian M.A. A single complementary-sense transcript of a geminiviral DNA beta satellite is determinant of pathogenicity. Molecular Plant-Microbe Interactions 2005, 18:7-14.
25. Sambrook L., Russell D.W. Molecular cloning: A laboratory manual. third ed 2001, Cold spring Harbor Laboratory Press, New York.
26. Voinnet O., Vain P., Angell S., Baulcombe D.C. Systemic spread of sequence-specific transgene RNA degradation in plants is initiated by localized introduction of ectopic promoterless DNA. Cell 1998, 95:177-187.