Validation of quantitative real-time PCR for the in vitro assessment of antileishmanial drug activity

Experimental Parasitology

Volumn 131, Issue 2, 2012, Pages 175-179

  Gomes, Luciana I ^a   Gonzaga, Felipe M ^a   Morais Teixeira, Eliane de ^a   de Souza Lima, Bruna S ^a   Freire, Verônica V ^a   Rabello, Ana ^a  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

Author keywords

Drug screening; In vitro assays; Leishmania; Quantitative real time PCR

Indexed keywords

AMPHOTERICIN B; ANFORICIN B; ANTILEISHMANIAL AGENT; UNCLASSIFIED DRUG;

ACCURACY; AMASTIGOTE; ANIMAL CELL; ANIMAL EXPERIMENT; ANTILEISHMANIAL ACTIVITY; ARTICLE; DNA DETERMINATION; DRUG ACTIVITY; DRUG DETERMINATION; DRUG SCREENING; HIGH THROUGHPUT SCREENING; HOST CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; LEISHMANIA INFANTUM; MICROSCOPY; MONOCYTE; MOUSE; NONHUMAN; PARASITE LOAD; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RELIABILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STANDARDIZATION; VALIDATION STUDY;

AMPHOTERICIN B; ANIMALS; ANTIPROTOZOAL AGENTS; CELLS, CULTURED; DNA, PROTOZOAN; DOSE-RESPONSE RELATIONSHIP, DRUG; INHIBITORY CONCENTRATION 50; LEISHMANIA INFANTUM; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED BALB C; REAL-TIME POLYMERASE CHAIN REACTION;

MURINAE;

EID: 84861482793     PISSN: 00144894     EISSN: 10902449     Source Type: Journal    
DOI: 10.1016/j.exppara.2012.03.021     Document Type: Article

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