Determination of the distribution of lentogenic vaccine and virulent Newcastle disease virus antigen in the oviduct of SPF and commercial hen using immunohistochemistry

Research in Veterinary Science

Volumn 93, Issue 1, 2012, Pages 520-528

  Bwala, Dauda G ^a,b   Clift, Sarah ^a   Duncan, Neil M ^a   Bisschop, Shahn P R ^a   Oludayo, Fasina F ^a  

^a UNIVERSITY OF PRETORIA   (South Africa)

^b NATIONAL VETERINARY RESEARCH INSTITUTE   (Nigeria)

Author keywords

GPMV; Hens; Immunohistochemistry; La sota vaccine; Newcastle disease

Indexed keywords

NEWCASTLE DISEASE VACCINE; VIRUS ANTIGEN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; CONTROLLED STUDY; CYTOPLASM; EDEMA; EGG PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; FEMALE; HEN; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MONONUCLEAR CELL; NEWCASTLE DISEASE; NEWCASTLE DISEASE PARAMYXOVIRUS; NONHUMAN; OVIDUCT; UTERUS; VIRAL TROPISM; VIRUS REPLICATION; VIRUS VIRULENCE;

ANIMALS; ANTIGENS, VIRAL; CHICKENS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; NEWCASTLE DISEASE; NEWCASTLE DISEASE VIRUS; OVIDUCTS; VIRAL VACCINES;

ANSER; AVES; NEWCASTLE DISEASE VIRUS; PARAMYXOVIRIDAE;

EID: 84861481653     PISSN: 00345288     EISSN: 15322661     Source Type: Journal    
DOI: 10.1016/j.rvsc.2011.06.023     Document Type: Article

References (37)

1. Alexander D.J. Newcastle disease and other avian paramyxoviruses. Review of Scientific Technical OIE 2000, 19:443-462.
2. Alexander D.J. Newcastle disease - the Gordon Memorial Lecture. British Poultry Science 2001, 42:5-22.
3. Al-Garib S.O., Gielkens A.L.J., Gruys E., Peeters B.P.H., Koch G. Tissue tropism in the chicken embryo of non-virulent Newcastle disease strains that express green fluorescence protein. Avian Pathology 2003, 32:591-596.
4. Allan W.H., Borland L.J. The stress index: a method for indicating the pathogenicity of vaccinal Newcastle disease virus when administered by aerosol. Avian Pathology 1979, 8:401-409.
5. Bancroft, J.D., Gamble, M. (Eds.), 2002. Theory and Practice of Histological Techniques, fifth ed. New York, Churchill Livingstone, 725p.
6. Beard C.W., Villegas P., Glisson J.R. Comparative efficacy of the B-1 and VG/GA vaccine strains against velogenic viscerotropic Newcastle disease virus in chickens. Avian Diseases 1993, 37:222-225.
7. Biswal G., Morrill C.C. The pathology of the reproductive tract of laying pullets affected with Newcastle disease. Poultry Science 1954, 33:881-897.
8. Brown C., King D.J., Seal B.S. Pathogenesis of Newcastle disease in chickens experimentally infected with viruses of different virulence. Veterinary Pathology 1999, 36:125-132.
9. Burridge M.J., Riemann H.P., Utterback W.W., Sharman E.C. The Newcastle disease epidemic in southern California, 1971-1973: descriptive epidemiology and effects of vaccination on the eradication program. Proceedings of the Annual Meeting of the U.S. Animal Health Association 1975, 79:324-333.
10. Clift S.J., Williams M.C., Gerdes T., Smit M.M.E. Standardization and validation of an immunoperoxidase assay for the detection of African horse sickness virus in formalin-fixed, paraffin-embedded tissues. Journal of Veterinary Diagnostic Investigation 2009, 21:655-667.
11. Czeglédi A., Ujvári D., Somogyi E., Wehmann E., Werner O., Lomniczi B. Third genome size category of avian paramyxovirus serotype 1 (Newcastle disease virus) and evolutionary implications. Virus Research 2006, 120:36-48.
12. Graphpad QuickCalcs (free Statistical Calculator). Available at: (accessed: 24.10.10). http://www.graphpad.com/quickcalcs/index.cfm.
13. Hamid H., Campbell R.S.F., Parede L. Studies on the pathology of velogenic Newcastle disease: virus infection in non-immune and immune birds. Avian Pathology 1991, 20:561-575.
14. Harwell M.R., Rubinstein E.N., Hayes W.S., Olds C.C. Summarizing Monte Carlo results in methodological research: the one- and two-factor fixed effects ANOVA cases. Journal of Education Statistics 1992, 17:315-339.
15. Holm L., Ekwall H., Ridderstråle Y. Calcium distribution and concentration in the domestic hen shell gland before and during shell formation. Avian Poultry Biology Reviews 2003, 4:207-208.
16. Kapczynski D.R., King D.J. Protection of chickens against overt clinical disease and determination of viral shedding following vaccination with commercially available Newcastle disease virus vaccines upon challenge with highly virulent virus from the California 2002 exotic Newcastle disease outbreak. Vaccine 2005, 23:3424-3433.
17. Kojnok J., Mészáros L., Gonye S. Immunization against Newcastle disease in Patridge. Magyar állatorvosok Lapja 1977, 32:311-313.
18. Kuiken T., Wobeser G., Leighton F.A., Haines D.M., Chelack B., Bogdan J., Hassard L., Heckert R.A., Riva J. Pathology of Newcastle disease in double-crested cormorants from Saskatchewan, with comparison of diagnostic methods. Journal of Wildlife Disease 1999, 35:8-23.
19. Lam K.M., Kabbur M.B., Eiserich J.P. Newcastle disease virus-induced functional impairments and biochemical changes in chicken heterophils. Veterinary Immunology and Immunopathology 1996, 53:313-327.
20. Lix L.M., Keselman J.C., Keselman H.J. Consequences of assumption violations revisited: a quantitative review of alternatives to the one-way analysis of variance F test. Review of Educational Research 1996, 66:579-619.
21. Lockaby S.B., Hoerr F.J., Ellis A.C., Yu M.S., Roberts C.S. Immunohistochemical detection of Newcastle disease virus in chickens. Avian Diseases 1993, 37:433-437.
22. Manzer, M., 2008. Paramyxovirus Type-1 IPX Stain. California Animal Health & Food Safety Laboratory (uncontrolled SOP), document # DHIS-02-716, July 17, 2008, Revision #1:1-4.
23. McFerran J.B., McCracken R.M. Newcastle disease. Newcastle Disease 1988, 161-183. Kluwer Academic Publishers, Boston. J.D. Alexander (Ed.).
24. Mészáros J.F. Control of infectious diseases in large-scale poultry breeding and production. World Poultry Science Journal 1983, 39:132-142.
25. Miller P.J., King D.J., Afonso C.L., Suarez D.L. Antigenic differences among Newcastle disease virus strains of different genotypes used in vaccine formulation affect viral shedding after a virulent challenge. Vaccine 2007, 25:7238-7246.
26. Ojok L., Brown C. Immunohistochemical study of the pathogenesis of virulent viscerotropic Newcastle disease in chickens. Journal of Comparative Pathology 1996, 115:221-227.
27. Oldoni I., Brown C.C., King D.J., Samal S., Seal B.S. The use of in situ hybridization and immunohistochemistry to study the pathogenesis of various Newcastle disease virus strains and recombinants in embryonated chicken eggs. Microbial Pathogenesis 2005, 39:69-75.
28. Parede L., Young P.L. The pathogenesis of velogenic Newcastle disease virus infection of chickens of different ages and different levels of immunity. Avian Diseases 1990, 34:803-808.
29. Perozo F., Villegas P., Dolz R., Afonso C.L., Purvis L.B. The VG/GA strain of Newcastle disease virus: mucosal immunity, protection against lethal challenge and molecular analysis. Avian Pathology 2008, 37:237-245.
30. Rao M.S., Dhinakar R.G., Manohar B.M. An in vitro and in vivo evaluation of the virulence of Newcastle disease virus and vaccines for the chicken reproductive tract. Avian Pathology 2002, 31:507-513.
31. Rehmani S.F. Newcastle disease vaccination: a comparison of vaccines and routes of administration in Pakistan. Preventive Veterinary Medicine 1996, 25:241-248.
32. Sharma, S.N., Adlakha, S.C., 1995. Viral pathogenesis In: Textbook of Veterinary Virology. Vikas Publishing House, PVT, Ltd., New Delhi, pp. 65-75.
33. Shi S.-R., Cote R.J., Taylor C.R. Antigen retrieval techniques: current perspectives. Journal of Histochemistry and Cytochemistry 2001, 49:931-937.
34. Sjaastad, Ø.V., Hove, K., Sand, O., 2003. Reproduction. In: Physiology of Domestic Animals. Scandinavian Veterinary Press, pp. 663-669.
35. Thornton D.H., Hopkins I.G., Hebert C.N. Potency of live Newcastle disease vaccines. Avian Pathology 1980, 9:457-464.
36. Wakamatsu N., King D.J., Seal B.S., Brown C.C. Detection of Newcastle disease virus RNA by reverse transcription polymerase Chain reaction using formalin-fixed, paraffin-embedded tisúes and comparison with immunohistochemistry and in-situ hybridization. Journal of Veterinary Diagnostic Investigation 2007, 19:396-400.
37. World Organization for Animal Health (OIE), 2010. Newcastle disease. In: Manual of Diagnostic Tests and Vaccines for Terrestrial Animals, Part 2, Section 2, Chapter 2.3.14, pp. 576-589. Also available online at: (accessed: 06.04.11). http://www.oie.int/fileadmin/Home/eng/Health_standards/tahm/2.03.14_NEWCASTLE_DIS.pdf.