메뉴 건너뛰기




Volumn 127, Issue 2, 2012, Pages 582-591

Mitochondrial dysfunction induced by sertraline, an antidepressant agent

Author keywords

Isolated liver mitochondria; Liver toxicity; Mitochondrial dysfunction; Rat primary hepatocytes; Sertraline

Indexed keywords

ADENINE NUCLEOTIDE TRANSLOCASE; ADENOSINE TRIPHOSPHATE; BONGKREKIC ACID; LACTATE DEHYDROGENASE; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SERTRALINE;

EID: 84861468623     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfs100     Document Type: Article
Times cited : (89)

References (55)
  • 1
    • 0022931338 scopus 로고
    • The reversible Ca2+-induced permeabilization of rat liver mitochondria
    • Al-Nasser, I., and Crompton, M. (1986). The reversible Ca2+-induced permeabilization of rat liver mitochondria. Biochem. J. 239, 19.
    • (1986) Biochem. J. , vol.239 , pp. 19
    • Al-Nasser, I.1    Crompton, M.2
  • 2
    • 33646100993 scopus 로고    scopus 로고
    • Caspase dependent alteration of the ADP/ATP translocator triggers the mitochondrial permeability transition which is not required for the low potassium dependent apoptosis of cerebellar granule cells
    • Atlante, A., Bobba, A., De Bari, L., Fontana, F., Calissano, P., Marra, E., and Passarella, S. (2006). Caspase dependent alteration of the ADP/ATP translocator triggers the mitochondrial permeability transition which is not required for the low potassium dependent apoptosis of cerebellar granule cells. J. Neurochem. 97, 1166-1181.
    • (2006) J. Neurochem. , vol.97 , pp. 1166-1181
    • Atlante, A.1    Bobba, A.2    De Bari, L.3    Fontana, F.4    Calissano, P.5    Marra, E.6    Passarella, S.7
  • 3
    • 0041803002 scopus 로고    scopus 로고
    • Cytochrome c, released from cerebellar granule cells undergoing apoptosis or excytotoxic death, can generate protonmotive force and drive ATP synthesis in isolated mitochondria
    • Atlante, A., de Bari, L., Bobba, A., Marra, E., Calissano, P., and Passarella, S. (2003). Cytochrome c, released from cerebellar granule cells undergoing apoptosis or excytotoxic death, can generate protonmotive force and drive ATP synthesis in isolated mitochondria. J. Neurochem. 86, 591-604.
    • (2003) J. Neurochem. , vol.86 , pp. 591-604
    • Atlante, A.1    de Bari, L.2    Bobba, A.3    Marra, E.4    Calissano, P.5    Passarella, S.6
  • 4
    • 0026492192 scopus 로고
    • Hépatotoxicité des médicaments: Mise a' jour du fichier bibliographique des atteintes hépatiques et des médicaments responsables
    • Biour, M., Poupon, R., Grange, J. D., Chazouilleres, O., Levy, V. G., Bodin, F., and Cheymol, G. (1992). Hépatotoxicité des médicaments: Mise a' jour du fichier bibliographique des atteintes hépatiques et des médicaments responsables. Gastroenterol. Clin. Biol. 16, 64-88.
    • (1992) Gastroenterol. Clin. Biol. , vol.16 , pp. 64-88
    • Biour, M.1    Poupon, R.2    Grange, J.D.3    Chazouilleres, O.4    Levy, V.G.5    Bodin, F.6    Cheymol, G.7
  • 5
    • 0024360271 scopus 로고
    • Cyclosporin A is a potent inhibitor of the inner membrane permeability transition in liver mitochondria
    • Broekemeier, K. M., Dempsey, M. E., and Pfeiffer, D. R. (1989). Cyclosporin A is a potent inhibitor of the inner membrane permeability transition in liver mitochondria. J. Biol. Chem. 264, 7826-7830.
    • (1989) J. Biol. Chem. , vol.264 , pp. 7826-7830
    • Broekemeier, K.M.1    Dempsey, M.E.2    Pfeiffer, D.R.3
  • 6
    • 77954426233 scopus 로고    scopus 로고
    • Sertraline hepatotoxicity: Report of a case and review of the literature
    • Collados, V., Hallal, H., and Andrade, R. J. (2010). Sertraline hepatotoxicity: Report of a case and review of the literature. Dig. Dis. Sci. 55, 1806-1807.
    • (2010) Dig. Dis. Sci. , vol.55 , pp. 1806-1807
    • Collados, V.1    Hallal, H.2    Andrade, R.J.3
  • 8
    • 0028075423 scopus 로고
    • Recruitment of mitochondrial cyclophilin to the mitochondrial inner membrane under conditions of oxidative stress that enhance the opening of a calcium-sensitive non-specific channel
    • Connern, C. P., and Halestrap, A. P. (1994). Recruitment of mitochondrial cyclophilin to the mitochondrial inner membrane under conditions of oxidative stress that enhance the opening of a calcium-sensitive non-specific channel. Biochem. J. 302(Pt 2), 321-324.
    • (1994) Biochem. J. , vol.302 , Issue.PART 2 , pp. 321-324
    • Connern, C.P.1    Halestrap, A.P.2
  • 9
    • 0033565557 scopus 로고    scopus 로고
    • The mitochondrial permeability transition pore and its role in cell death
    • Crompton, M. (1999). The mitochondrial permeability transition pore and its role in cell death. Biochem. J. 341(Pt 2), 233-249.
    • (1999) Biochem. J. , vol.341 , Issue.PART 2 , pp. 233-249
    • Crompton, M.1
  • 10
    • 0031960743 scopus 로고    scopus 로고
    • Preclinical toxicological evaluation of sertraline hydrochloride
    • Davies, T. S., and Kluwe, W. M. (1998). Preclinical toxicological evaluation of sertraline hydrochloride. Drug Chem. Toxicol. 21, 521-537.
    • (1998) Drug Chem. Toxicol. , vol.21 , pp. 521-537
    • Davies, T.S.1    Kluwe, W.M.2
  • 12
  • 13
    • 34047154993 scopus 로고    scopus 로고
    • Strategies to reduce latestage drug attrition due to mitochondrial toxicity
    • Dykens, J. A., Marroquin, L. D., and Will, Y. (2007). Strategies to reduce latestage drug attrition due to mitochondrial toxicity. Expert Rev. Mol. Diagn. 7, 161-175.
    • (2007) Expert Rev. Mol. Diagn. , vol.7 , pp. 161-175
    • Dykens, J.A.1    Marroquin, L.D.2    Will, Y.3
  • 16
    • 34347236921 scopus 로고    scopus 로고
    • Organelle isolation: Functional mitochondria from mouse liver, muscle and cultured fibroblasts
    • Frezza, C., Cipolat, S., and Scorrano, L. (2007). Organelle isolation: Functional mitochondria from mouse liver, muscle and cultured fibroblasts. Nat. Protoc. 2, 287-295.
    • (2007) Nat. Protoc. , vol.2 , pp. 287-295
    • Frezza, C.1    Cipolat, S.2    Scorrano, L.3
  • 17
    • 0035714271 scopus 로고    scopus 로고
    • Hepatitis aguda colestásica probablemente causada por sertralina
    • Galán Navarro, J. (2001). Hepatitis aguda colestásica probablemente causada por sertralina. Rev. Esp. Enferm. Dig. 93, 822.
    • (2001) Rev. Esp. Enferm. Dig. , vol.93 , pp. 822
    • Galán Navarro, J.1
  • 18
    • 79951922704 scopus 로고    scopus 로고
    • Similarities and differences in the expression of drug-metabolizing enzymes between human hepatic cell lines and primary human hepatocytes
    • Guo, L., Dial, S., Shi, L., Branham, W., Liu, J., Fang, J. L., Green, B., Deng, H., Kaput, J., and Ning, B. (2011). Similarities and differences in the expression of drug-metabolizing enzymes between human hepatic cell lines and primary human hepatocytes. Drug Metab. Dispos. 39, 528-538.
    • (2011) Drug Metab. Dispos. , vol.39 , pp. 528-538
    • Guo, L.1    Dial, S.2    Shi, L.3    Branham, W.4    Liu, J.5    Fang, J.L.6    Green, B.7    Deng, H.8    Kaput, J.9    Ning, B.10
  • 19
    • 33947308562 scopus 로고    scopus 로고
    • Differential gene expression in mouse primary hepatocytes exposed to the peroxisome proliferator-activated receptor a agonists
    • Guo, L., Fang, H., Collins, J., Fan, X., Dial, S., Wong, A., Mehta, K., Blann, E., Shi, L., and Tong, W. (2006a). Differential gene expression in mouse primary hepatocytes exposed to the peroxisome proliferator-activated receptor a agonists. BMC Bioinformatics 7, S18.
    • (2006) BMC Bioinformatics , vol.7
    • Guo, L.1    Fang, H.2    Collins, J.3    Fan, X.4    Dial, S.5    Wong, A.6    Mehta, K.7    Blann, E.8    Shi, L.9    Tong, W.10
  • 20
    • 33749584932 scopus 로고    scopus 로고
    • Differences in hepatotoxicity and gene expression profiles by anti-diabetic PPAR gamma agonists on rat primary hepatocytes and human HepG2 cells
    • Guo, L., Zhang, L., Sun, Y., Muskhelishvili, L., Blann, E., Dial, S., Shi, L., Schroth, G., and Dragan, Y. P. (2006b). Differences in hepatotoxicity and gene expression profiles by anti-diabetic PPAR gamma agonists on rat primary hepatocytes and human HepG2 cells. Mol. Divers. 10, 349-360.
    • (2006) Mol. Divers. , vol.10 , pp. 349-360
    • Guo, L.1    Zhang, L.2    Sun, Y.3    Muskhelishvili, L.4    Blann, E.5    Dial, S.6    Shi, L.7    Schroth, G.8    Dragan, Y.P.9
  • 23
    • 84924837411 scopus 로고
    • Cytochemical studies of mammalian tissues: I Isolation of intact mitochondria from rat liver; some biochemical properties of mitochondria and submicroscopic particulate material
    • Hogeboom, G. H., Schneider, W. C., and Pallade, G. E. (1948). Cytochemical studies of mammalian tissues: I. Isolation of intact mitochondria from rat liver; some biochemical properties of mitochondria and submicroscopic particulate material. J. Biol. Chem. 172, 619.
    • (1948) J. Biol. Chem. , vol.172 , pp. 619
    • Hogeboom, G.H.1    Schneider, W.C.2    Pallade, G.E.3
  • 25
    • 0038584862 scopus 로고    scopus 로고
    • Protection from inactivation of the adenine nucleotide translocator during hypoglycaemia-induced apoptosis by mitochondrial phospholipid hydroperoxide glutathione peroxidase
    • Imai, H., Koumura, T., Nakajima, R., Nomura, K., and Nakagawa, Y. (2003). Protection from inactivation of the adenine nucleotide translocator during hypoglycaemia-induced apoptosis by mitochondrial phospholipid hydroperoxide glutathione peroxidase. Biochem. J. 371, 799-809.
    • (2003) Biochem. J. , vol.371 , pp. 799-809
    • Imai, H.1    Koumura, T.2    Nakajima, R.3    Nomura, K.4    Nakagawa, Y.5
  • 26
    • 0032895772 scopus 로고    scopus 로고
    • Acute liver damage possibly related to sertraline and venlafaxine ingestion
    • Kim, K. Y., Hwang, W., and Narendran, R. (1999). Acute liver damage possibly related to sertraline and venlafaxine ingestion. Ann. Pharmacother. 33, 381-382.
    • (1999) Ann. Pharmacother. , vol.33 , pp. 381-382
    • Kim, K.Y.1    Hwang, W.2    Narendran, R.3
  • 27
    • 34147164476 scopus 로고    scopus 로고
    • Biochemical assays of respiratory chain complex activity
    • L. Wilson and P. Matsudaira, Eds. Academic Press, San Diego CA
    • Kirby, D., Thorburn, D., Turnbull, D., and Taylor, R. (2007). Biochemical assays of respiratory chain complex activity. In Methods in Cell Biology (L. Wilson and P. Matsudaira, Eds.), pp. 93-119. Academic Press, San Diego, CA.
    • (2007) Methods in Cell Biology , pp. 93-119
    • Kirby, D.1    Thorburn, D.2    Turnbull, D.3    Taylor, R.4
  • 28
    • 0015887496 scopus 로고
    • On the mechanism of bongkrekate effect on the mitochondrial adenine-nucleotide carrier as studied through the binding of ADP
    • Klingenberg, M., and Buchholz, M. (1973). On the mechanism of bongkrekate effect on the mitochondrial adenine-nucleotide carrier as studied through the binding of ADP. Eur. J. Biochem. 38, 346-358.
    • (1973) Eur. J. Biochem. , vol.38 , pp. 346-358
    • Klingenberg, M.1    Buchholz, M.2
  • 29
    • 0021038289 scopus 로고
    • An enzyme-release assay for natural cytotoxicity
    • Korzeniewski, C., and Callewaert, D. M. (1983). An enzyme-release assay for natural cytotoxicity. J. Immunol. Methods 64, 313-320.
    • (1983) J. Immunol. Methods , vol.64 , pp. 313-320
    • Korzeniewski, C.1    Callewaert, D.M.2
  • 30
    • 0022511846 scopus 로고
    • Use of a low-speed, iso-density Percoll centrifugation method to increase the viability of isolated rat hepatocyte preparations
    • Kreamer, B. L., Staecker, J. L., Sawada, N., Sattler, G. L., Hsia, M. T. S., and Pitot, H. C. (1986). Use of a low-speed, iso-density Percoll centrifugation method to increase the viability of isolated rat hepatocyte preparations. In Vitro Cell. Dev. Biol. Plant 22, 201-211.
    • (1986) Vitro Cell. Dev. Biol. Plant , vol.22 , pp. 201-211
    • Kreamer, B.L.1    Staecker, J.L.2    Sawada, N.3    Sattler, G.L.4    Hsia, M.T.S.5    Pitot, H.C.6
  • 31
    • 0024324896 scopus 로고
    • A critical appraisal of the association between energy charge and cell damage
    • Kristensen, S. R. (1989). A critical appraisal of the association between energy charge and cell damage. Biochim. Biophys. Acta Mol. Cell Res. 1012, 272-278
    • (1989) Biochim. Biophys. Acta Mol. Cell Res. , vol.1012 , pp. 272-278
    • Kristensen, S.R.1
  • 32
    • 33845977959 scopus 로고    scopus 로고
    • Mitochondrial membrane permeabilization in cell death
    • Kroemer, G., Galluzzi, L., and Brenner, C. (2007). Mitochondrial membrane permeabilization in cell death. Physiol. Rev. 87, 99-163
    • (2007) Physiol. Rev. , vol.87 , pp. 99-163
    • Kroemer, G.1    Galluzzi, L.2    Brenner, C.3
  • 33
    • 55949124005 scopus 로고    scopus 로고
    • Drug-induced liver injury through mitochondrial dysfunction: Mechanisms and detection during preclinical safety studies
    • Labbe, G., Pessayre, D., and Fromenty, B. (2008). Drug-induced liver injury through mitochondrial dysfunction: Mechanisms and detection during preclinical safety studies. Fundam. Clin. Pharmacol. 22, 335-353.
    • (2008) Fundam. Clin. Pharmacol. , vol.22 , pp. 335-353
    • Labbe, G.1    Pessayre, D.2    Fromenty, B.3
  • 34
    • 0041342015 scopus 로고    scopus 로고
    • Drug-induced hepatotoxicity
    • Lee, W. M. (2003). Drug-induced hepatotoxicity. N. Engl. J. Med. 349, 474-485.
    • (2003) N. Engl. J. Med. , vol.349 , pp. 474-485
    • Lee, W.M.1
  • 35
    • 0037163117 scopus 로고    scopus 로고
    • Mitochondrial targeted cyclophilin D protects cells from cell death by peptidyl prolyl isomerization
    • Lin, D. T., and Lechleiter, J. D. (2002). Mitochondrial targeted cyclophilin D protects cells from cell death by peptidyl prolyl isomerization. J. Biol. Chem. 277, 31134-31141.
    • (2002) J. Biol. Chem. , vol.277 , pp. 31134-31141
    • Lin, D.T.1    Lechleiter, J.D.2
  • 36
    • 34447577912 scopus 로고    scopus 로고
    • Circumventing the Crabtree effect: Replacing media glucose with galactose increases susceptibility of HepG2 cells to mitochondrial toxicants
    • Marroquin, L. D., Hynes, J., Dykens, J. A., Jamieson, J. D., and Will, Y. (2007). Circumventing the Crabtree effect: Replacing media glucose with galactose increases susceptibility of HepG2 cells to mitochondrial toxicants. Toxicol. Sci. 97, 539-547.
    • (2007) Toxicol. Sci. , vol.97 , pp. 539-547
    • Marroquin, L.D.1    Hynes, J.2    Dykens, J.A.3    Jamieson, J.D.4    Will, Y.5
  • 37
    • 77954425997 scopus 로고    scopus 로고
    • Mujer de mediana edad con prurito y patrón analítico de colestasis aguda
    • Martínez Matos, Y. (2002). Mujer de mediana edad con prurito y patrón analítico de colestasis aguda. SEMERGEN 28, 105-107.
    • (2002) SEMERGEN , vol.28 , pp. 105-107
    • Martínez Matos, Y.1
  • 38
    • 33646112416 scopus 로고    scopus 로고
    • Mitochondrial permeability transition as a potential determinant of hepatotoxicity of antidiabetic thiazolidinediones
    • Masubuchi, Y., Kano, S., and Horie, T. (2006). Mitochondrial permeability transition as a potential determinant of hepatotoxicity of antidiabetic thiazolidinediones. Toxicology 222, 233-239.
    • (2006) Toxicology , vol.222 , pp. 233-239
    • Masubuchi, Y.1    Kano, S.2    Horie, T.3
  • 39
    • 0032811572 scopus 로고    scopus 로고
    • Diphenylamine as an important structure of nonsteroidal anti-inflammatory drugs to uncouple mitochondrial oxidative phosphorylation
    • Masubuchi, Y., Yamada, S., and Horie, T. (1999). Diphenylamine as an important structure of nonsteroidal anti-inflammatory drugs to uncouple mitochondrial oxidative phosphorylation. Biochem. Pharmacol. 58, 861-865.
    • (1999) Biochem. Pharmacol. , vol.58 , pp. 861-865
    • Masubuchi, Y.1    Yamada, S.2    Horie, T.3
  • 40
    • 34347250517 scopus 로고    scopus 로고
    • Troglitazone-induced hepatic necrosis in an animal model of silent genetic mitochondrial abnormalities
    • Ong, M. M., Latchoumycandane, C., and Boelsterli, U. A. (2007). Troglitazone-induced hepatic necrosis in an animal model of silent genetic mitochondrial abnormalities. Toxicol. Sci. 97, 205-213.
    • (2007) Toxicol. Sci. , vol.97 , pp. 205-213
    • Ong, M.M.1    Latchoumycandane, C.2    Boelsterli, U.A.3
  • 41
    • 0037404964 scopus 로고    scopus 로고
    • Sertraline hepatotoxicity: A case report and review of the literature on selective serotonin reuptake inhibitor hepatotoxicity
    • Persky, S., and Reinus, J. F. (2003). Sertraline hepatotoxicity: A case report and review of the literature on selective serotonin reuptake inhibitor hepatotoxicity. Dig. Dis. Sci. 48, 939-944.
    • (2003) Dig. Dis. Sci. , vol.48 , pp. 939-944
    • Persky, S.1    Reinus, J.F.2
  • 42
    • 0034177951 scopus 로고    scopus 로고
    • Tissue variation in the control of oxidative phosphorylation: Implication for mitochondrial diseases
    • Rossignol, R., Letellier, T., Malgat, M., Rocher, C., and Mazat, J. P. (2000). Tissue variation in the control of oxidative phosphorylation: Implication for mitochondrial diseases. Biochem. J. 347(Pt 1), 45-53.
    • (2000) Biochem. J. , vol.347 , Issue.PART 1 , pp. 45-53
    • Rossignol, R.1    Letellier, T.2    Malgat, M.3    Rocher, C.4    Mazat, J.P.5
  • 43
    • 0023032060 scopus 로고
    • On central effects of serotonin re-uptake inhibitors: Quantitative EEG and psychometric studies with sertraline and zimelidine
    • Saletu, B., Grunberger, J., and Linzmayer, L. (1986). On central effects of serotonin re-uptake inhibitors: Quantitative EEG and psychometric studies with sertraline and zimelidine. J. Neural Transm. 67, 241-266.
    • (1986) J. Neural Transm. , vol.67 , pp. 241-266
    • Saletu, B.1    Grunberger, J.2    Linzmayer, L.3
  • 44
  • 45
    • 0017101039 scopus 로고
    • Preparation of isolated rat liver cells
    • Seglen, P. O. (1976). Preparation of isolated rat liver cells. Methods Cell Biol. 13, 29-83.
    • (1976) Methods Cell Biol , vol.13 , pp. 29-83
    • Seglen, P.O.1
  • 47
    • 33748961353 scopus 로고    scopus 로고
    • Mitochondrial membrane permeability transition and cell death
    • Tsujimoto, Y., Nakagawa, T., and Shimizu, S. (2006). Mitochondrial membrane permeability transition and cell death. Biochim. Biophys. Acta 1757, 1297-1300.
    • (2006) Biochim. Biophys. Acta , vol.1757 , pp. 1297-1300
    • Tsujimoto, Y.1    Nakagawa, T.2    Shimizu, S.3
  • 49
    • 0034543763 scopus 로고    scopus 로고
    • Fulminant chemical hepatitis possibly associated with donepezil and sertraline therapy
    • Verrico, M. M., Nace, D. A., and Towers, A. L. (2000). Fulminant chemical hepatitis possibly associated with donepezil and sertraline therapy. J. Am. Geriatr. Soc. 48, 1659-1663.
    • (2000) J. Am. Geriatr. Soc. , vol.48 , pp. 1659-1663
    • Verrico, M.M.1    Nace, D.A.2    Towers, A.L.3
  • 50
    • 0021765406 scopus 로고
    • Factors determining the relative contribution of the adenine-nucleotide translocator and the ADP-regenerating system to the control of oxidative phosphorylation in isolated rat-liver mitochondria
    • Wanders, R. J., Groen, A. K., Van Roermund, C. W., and Tager, J. M. (1984). Factors determining the relative contribution of the adenine-nucleotide translocator and the ADP-regenerating system to the control of oxidative phosphorylation in isolated rat-liver mitochondria. Eur. J. Biochem. 142, 417-424.
    • (1984) Eur. J. Biochem. , vol.142 , pp. 417-424
    • Wanders, R.J.1    Groen, A.K.2    Van Roermund, C.W.3    Tager, J.M.4
  • 51
  • 52
    • 0026291671 scopus 로고
    • Clinical implications of the pharmacology of sertraline
    • Warrington, S. J. (1991). Clinical implications of the pharmacology of sertraline. Int. Clin. Psychopharmacol. 6(Suppl. 2), 11-21.
    • (1991) Int. Clin. Psychopharmacol. , vol.6 , Issue.SUPPL. 2 , pp. 11-21
    • Warrington, S.J.1
  • 53
    • 0032568261 scopus 로고    scopus 로고
    • Hepatic dysfunction associated with troglitazone
    • Watkins, P. B., and Whitcomb, R. W. (1998). Hepatic dysfunction associated with troglitazone. N. Engl. J. Med. 338, 916-917.
    • (1998) N. Engl. J. Med. , vol.338 , pp. 916-917
    • Watkins, P.B.1    Whitcomb, R.W.2
  • 55
    • 84861478026 scopus 로고    scopus 로고
    • Zoloft, (Sertraline Hydrochloride) Package Insert, New York, NY
    • Zoloft (1997). Roering Division of Pfizer, Inc. Zoloft (Sertraline Hydrochloride) Package Insert, New York, NY.
    • (1997) Roering Division of Pfizer, Inc


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.