Inactivation of Dicer1 has a severe cumulative impact on the formation of mature germ cells in mouse testes

Biochemical and Biophysical Research Communications

Volumn 422, Issue 1, 2012, Pages 114-120

  Liu, Dekang ^a   Li, Liangyun ^a   Fu, Heling ^a   Li, Shuzhen ^a   Li, Jianmin ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Dicer1; Round spermatids; Spermatogenesis; Sterility

Indexed keywords

DICER; DICER1; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL COUNT; CELL FUNCTION; CELL MATURATION; CELL STRUCTURE; CONTROLLED STUDY; EPIDIDYMIS; GERM CELL; HAPLOIDY; MEIOSIS; MOUSE; NICK END LABELING; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SEMINIFEROUS TUBULE; SPERMATID; SPERMATOCYTE; SPERMATOGENESIS; SPERMATOGONIUM; SPERMATOZOON; TESTIS;

ANIMALS; DEAD-BOX RNA HELICASES; FEMALE; FERTILITY; MALE; MEIOSIS; MICE; MICE, MUTANT STRAINS; RIBONUCLEASE III; SPERMATOCYTES; SPERMATOGENESIS; SPERMATOZOA; TESTIS;

MUS; MUS MUSCULUS;

EID: 84861457045     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.04.118     Document Type: Article

References (34)

1. Braun R.E. Post-transcriptional control of gene expression during spermatogenesis. Semin. Cell Dev. Biol. 1998, 9:483-489.
2. Pillai R.S., Bhattacharyya S.N., Filipowicz W. Repression of protein synthesis by miRNAs: how many mechanisms?. Trends Cell Biol. 2007, 17:118-126.
3. Lee R.C., Feinbaum R.L., Ambros V. The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 1993, 75:843-854.
4. Hutvagner G., Zamore P.D. A microRNA in a multiple-turnover RNAi enzyme complex. Science 2002, 297:2056-2060.
5. Yekta S., Shih I.H., Bartel D.P. MicroRNA-directed cleavage of HOXB8 mRNA. Science 2004, 304:594-596.
6. Wightman B., Ha I., Ruvkun G. Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell 1993, 75:855-862.
7. Lim L.P., Lau N.C., Garrett-Engele P., Grimson A., Schelter J.M., Castle J., Bartel D.P., Linsley P.S., Johnson J.M. Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 2005, 433:769-773.
8. Friedman R.C., Farh K.K., Burge C.B., Bartel D.P. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res. 2009, 19:92-105.
9. Bartel D.P. MicroRNAs: target recognition and regulatory functions. Cell 2009, 136:215-233.
10. Zhang B., Pan X., Anderson T.A. MicroRNA: a new player in stem cells. J. Cell Physiol. 2006, 209:266-269.
11. Kanellopoulou C., Muljo S.A., Kung A.L., Ganesan S., Drapkin R., Jenuwein T., Livingston D.M., Rajewsky K. Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing. Genes Dev. 2005, 19:489-501.
12. Harris K.S., Zhang Z., McManus M.T., Harfe B.D., Sun X. Dicer function is essential for lung epithelium morphogenesis. Proc. Natl. Acad. Sci. USA 2006, 103:2208-2213.
13. Andl T., Murchison E.P., Liu F., Zhang Y., Yunta-Gonzalez M., Tobias J.W., Andl C.D., Seykora J.T., Hannon G.J., Millar S.E. The miRNA-processing enzyme dicer is essential for the morphogenesis and maintenance of hair follicles. Curr. Biol. 2006, 16:1041-1049.
14. Yang W.J., Yang D.D., Na S., Sandusky G.E., Zhang Q., Zhao G. Dicer is required for embryonic angiogenesis during mouse development. J. Biol. Chem. 2005, 280:9330-9335.
15. Muljo S.A., Ansel K.M., Kanellopoulou C., Livingston D.M., Rao A., Rajewsky K. Aberrant T cell differentiation in the absence of Dicer. J. Exp. Med. 2005, 202:261-269.
16. Luense L.J., Carletti M.Z., Christenson L.K. Role of Dicer in female fertility. Trends Endocrinol. Metab. 2009, 20:265-272.
17. K. Hayashi, S.M. Chuva de Sousa Lopes, M. Kaneda, F. Tang, P. Hajkova, K. Lao, D. O'Carroll, P.P. Das, A. Tarakhovsky, E.A. Miska, M.A. Surani, MicroRNA biogenesis is required for mouse primordial germ cell development and spermatogenesis, PLoS One 3 (2008) e1738.
18. Yu Z., Raabe T., Hecht N.B. MicroRNA Mirn122a reduces expression of the posttranscriptionally regulated germ cell transition protein 2 (Tnp2) messenger RNA (mRNA) by mRNA cleavage. Biol. Reprod. 2005, 73:427-433.
19. Ro S., Park C., Sanders K.M., McCarrey J.R., Yan W. Cloning and expression profiling of testis-expressed microRNAs. Dev. Biol. 2007, 311:592-602.
20. Denli A.M., Tops B.B., Plasterk R.H., Ketting R.F., Hannon G.J. Processing of primary microRNAs by the microprocessor complex. Nature 2004, 432:231-235.
21. Bernstein E., Kim S.Y., Carmell M.A., Murchison E.P., Alcorn H., Li M.Z., Mills A.A., Elledge S.J., Anderson K.V., Hannon G.J. Dicer is essential for mouse development. Nat. Genet. 2003, 35:215-217.
22. Maatouk D.M., Loveland K.L., McManus M.T., Moore K., Harfe B.D. Dicer1 is required for differentiation of the mouse male germline. Biol. Reprod. 2008, 79:696-703.
23. Lomeli H., Ramos-Mejia V., Gertsenstein M., Lobe C.G., Nagy A. Targeted insertion of Cre recombinase into the TNAP gene: excision in primordial germ cells. Genesis 2000, 26:116-117.
24. Harfe B.D., McManus M.T., Mansfield J.H., Hornstein E., Tabin C.J. The RNaseIII enzyme Dicer is required for morphogenesis but not patterning of the vertebrate limb. Proc. Natl. Acad. Sci. USA 2005, 102:10898-10903.
25. Gallardo T., Shirley L., John G.B., Castrillon D.H. Generation of a germ cell-specific mouse transgenic Cre line. Vasa-Cre. Genesis 2007, 45:413-417.
26. Chen J.F., Murchison E.P., Tang R., Callis T.E., Tatsuguchi M., Deng Z., Rojas M., Hammond S.M., Schneider M.D., Selzman C.H., Meissner G., Patterson C., Hannon G.J., Wang D.Z. Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc. Natl. Acad. Sci. USA 2008, 105:2111-2116.
27. Sadate-Ngatchou P.I., Payne C.J., Dearth A.T., Braun R.E. Cre recombinase activity specific to postnatal, premeiotic male germ cells in transgenic mice. Genesis 2008, 46:738-742.
28. Kido T., Arata S., Suzuki R., Hosono T., Nakanishi Y., Miyazaki J., Saito I., Kuroki T., Shioda S. The testicular fatty acid binding protein PERF15 regulates the fate of germ cells in PERF15 transgenic mice. Dev. Growth Differ. 2005, 47:15-24.
29. Buchold G.M., Coarfa C., Kim J., Milosavljevic A., Gunaratne P.H., Matzuk M.M. Analysis of microRNA expression in the prepubertal testis. PLoS. 2010, 5:e15317.
30. Chiosea S., Jelezcova E., Chandran U., Luo J., Mantha G., Sobol R.W., Dacic S. Overexpression of Dicer in precursor lesions of lung adenocarcinoma. Cancer Res. 2007, 67:2345-2350.
31. Jakymiw A., Patel R.S., Deming N., Bhattacharyya I., Shah P., Lamont R.J., Stewart C.M., Cohen D.M., Chan E.K. Overexpression of dicer as a result of reduced let-7 MicroRNA levels contributes to increased cell proliferation of oral cancer cells. Genes Chromosomes Cancer 2010, 49:549-559.
32. Chiosea S., Jelezcova E., Chandran U., Acquafondata M., McHale T., Sobol R.W., Dhir R. Up-regulation of dicer, a component of the MicroRNA machinery, in prostate adenocarcinoma. Am. J. Pathol. 2006, 169:1812-1820.
33. Kotaja N., Bhattacharyya S.N., Jaskiewicz L., Kimmins S., Parvinen M., Filipowicz W., Sassone-Corsi P. The chromatoid body of male germ cells: similarity with processing bodies and presence of Dicer and microRNA pathway components. Proc. Natl. Acad. Sci. USA 2006, 103:2647-2652.
34. Shang P., Baarends W.M., Hoogerbrugge J., Ooms M.P., van Cappellen W.A., de Jong A.A., Dohle G.R., van Eenennaam H., Gossen J.A., Grootegoed J.A. Functional transformation of the chromatoid body in mouse spermatids requires testis-specific serine/threonine kinases. J. Cell Sci. 2010, 123:331-339.