메뉴 건너뛰기




Volumn 40, Issue 9, 2012, Pages

An on-bead tailing/ligation approach for sequencing resin-bound RNA libraries

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; DNA ADAPTER; NUCLEIC ACID BASE; NUCLEOSIDE; NUCLEOTIDE; OLIGONUCLEOTIDE; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; POLYNUCLEOTIDE ADENYLYLTRANSFERASE; POLYSTYRENE; RESIN; RNA; UNCLASSIFIED DRUG;

EID: 84861392530     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gks004     Document Type: Article
Times cited : (2)

References (52)
  • 1
    • 35148840942 scopus 로고    scopus 로고
    • Functional aptamers and aptazymes in biotechnology, diagnostics, and therapy
    • DOI 10.1021/cr0306743
    • Famulok, M., Hartig, J.S. and Mayer, G. (2007) Functional aptamers and aptazymes in biotechnology, diagnostics, and therapy. Chem. Rev., 107, 3715-3743. (Pubitemid 47534316)
    • (2007) Chemical Reviews , vol.107 , Issue.9 , pp. 3715-3743
    • Famulok, M.1    Hartig, J.S.2    Mayer, G.3
  • 2
    • 34548311711 scopus 로고    scopus 로고
    • Forty years of in vitro evolution
    • DOI 10.1002/anie.200701369
    • Joyce, G.F. (2007) Forty years of in vitro evolution. Angew. Chem. Int. Ed., 46, 6420-6436. (Pubitemid 47340165)
    • (2007) Angewandte Chemie - International Edition , vol.46 , Issue.34 , pp. 6420-6436
    • Joyce, G.F.1
  • 4
    • 0025074907 scopus 로고
    • In vitro selection of RNA molecules that bind specific ligands
    • Ellington, A.D. and Szostak, J.W. (1990) In vitro selection of RNA molecules that bind specific ligands. Nature, 346, 818-822.
    • (1990) Nature , vol.346 , pp. 818-822
    • Ellington, A.D.1    Szostak, J.W.2
  • 5
    • 0025194307 scopus 로고
    • Systematic evolution of ligands by exponential enrichment-RNA ligands to bacteriophage-T4 DNA-polymerase
    • Tuerk, C. and Gold, L. (1990) Systematic evolution of ligands by exponential enrichment-RNA ligands to bacteriophage-T4 DNA-polymerase. Science, 249, 505-510.
    • (1990) Science , vol.249 , pp. 505-510
    • Tuerk, C.1    Gold, L.2
  • 6
    • 0025332385 scopus 로고
    • Selection in vitro of an RNA enzyme that specifically cleaves single-stranded DNA
    • Robertson, D.L. and Joyce, G.F. (1990) Selection in vitro of an RNA enzyme that specifically cleaves single-stranded DNA. Nature, 344, 467-468.
    • (1990) Nature , vol.344 , pp. 467-468
    • Robertson, D.L.1    Joyce, G.F.2
  • 7
    • 0035844150 scopus 로고    scopus 로고
    • Systematic evolution of a DNA aptamer binding to rat brain tumor microvessels-selective targeting of endothelial regulatory protein pigpen
    • Blank, M., Weinschenk, T., Priemer, M. and Schluesener, H. (2001) Systematic evolution of a DNA aptamer binding to rat brain tumor microvessels-selective targeting of endothelial regulatory protein pigpen. J. Biol. Chem., 276, 16464-16468.
    • (2001) J. Biol. Chem. , vol.276 , pp. 16464-16468
    • Blank, M.1    Weinschenk, T.2    Priemer, M.3    Schluesener, H.4
  • 8
    • 21244434234 scopus 로고    scopus 로고
    • Selection of RNA aptamers against human influenza virus hemagglutinin using surface plasmon resonance
    • DOI 10.1016/j.ab.2005.04.013, PII S000326970500309X
    • Misono, T.S. and Kumar, P.K.R. (2005) Selection of RNA aptamers against human influenza virus hemagglutinin using surface plasmon resonance. Anal. Biochem., 342, 312-317. (Pubitemid 40884581)
    • (2005) Analytical Biochemistry , vol.342 , Issue.2 , pp. 312-317
    • Misono, T.S.1    Kumar, P.K.R.2
  • 9
    • 0347760143 scopus 로고    scopus 로고
    • In vitro evolution of functional DNA using capillary electrophoresis
    • Mendonsa, S.D. and Bowser, M.T. (2004) In vitro evolution of functional DNA using capillary electrophoresis. J. Am. Chem. Soc., 126, 20-21. (Pubitemid 38090319)
    • (2004) Journal of the American Chemical Society , vol.126 , Issue.1 , pp. 20-21
    • Mendonsa, S.D.1    Bowser, M.T.2
  • 11
    • 0026419328 scopus 로고
    • A new type of synthetic peptide library for identifying ligand-binding activity
    • Lam, K.S., Salmon, S.E., Hersh, E.M., Hruby, V.J., Kazmierski, W.M. and Knapp, R.J. (1991) A new type of synthetic peptide library for identifying ligand-binding activity. Nature, 354, 82-84. (Pubitemid 21896787)
    • (1991) Nature , vol.354 , Issue.6348 , pp. 82-84
    • Lam, K.S.1    Salmon, S.E.2    Hersh, E.M.3    Hruby, V.J.4    Kazmierskit, W.M.5    Knappt, R.J.6
  • 12
    • 9144222282 scopus 로고    scopus 로고
    • Construction and selection of bead-bound combinatorial oligonucleoside phosphorothioate and phosphorodithioate aptamer libraries designed for rapid PCR-based sequencing
    • Yang, X., Bassett, S.E., Li, X., Luxon, B.A., Herzog, N.K., Shope, R.E., Aronson, J., Prow, T.W., Leary, J.F., Kirby, R. et al. (2002) Construction and selection of bead-bound combinatorial oligonucleoside phosphorothioate and phosphorodithioate aptamer libraries designed for rapid PCR-based sequencing. Nucleic Acids Res., 30, e132/131-e132/138.
    • (2002) Nucleic Acids Res. , vol.30
    • Yang, X.1    Bassett, S.E.2    Li, X.3    Luxon, B.A.4    Herzog, N.K.5    Shope, R.E.6    Aronson, J.7    Prow, T.W.8    Leary, J.F.9    Kirby, R.10
  • 13
    • 79551489562 scopus 로고    scopus 로고
    • Isolation and characterization of fluorescence-enhancing RNA tags
    • Wiesmayr, A. and Jäschke, A. (2011) Isolation and characterization of fluorescence-enhancing RNA tags. Bioorg. Med. Chem., 19, 1041-1047.
    • (2011) Bioorg. Med. Chem. , vol.19 , pp. 1041-1047
    • Wiesmayr, A.1    Jäschke, A.2
  • 14
    • 39749203611 scopus 로고    scopus 로고
    • Gas chromatographic high-throughput screening techniques in catalysis
    • DOI 10.1016/j.chroma.2007.10.086, PII S0021967307018675
    • Trapp, O. (2008) Gas chromatographic high-throughput screening techniques in catalysis. J. Chromatogr. A, 1184, 160-190. (Pubitemid 351296223)
    • (2008) Journal of Chromatography A , vol.1184 , Issue.1-2 , pp. 160-190
    • Trapp, O.1
  • 15
    • 0035910597 scopus 로고    scopus 로고
    • Combinatorial and evolution-based methods in the creation of enantioselective catalysts
    • DOI 10.1002/1521-3773(20010119)40:2<284::AID-ANIE284>3.0.CO;2-N
    • Reetz, M.T. (2001) Combinatorial and evolution-based methods in the creation of enantioselective catalysts. Angew. Chem. Int. Ed., 40, 284-310. (Pubitemid 32117656)
    • (2001) Angewandte Chemie - International Edition , vol.40 , Issue.2 , pp. 284-310
    • Reetz, M.T.1
  • 16
    • 27144444307 scopus 로고    scopus 로고
    • Size, constant sequences, and optimal selection
    • DOI 10.1261/rna.2161305
    • Legiewicz, M., Lozupone, C., Knight, R. and Yarus, M. (2005) Size, constant sequences, and optimal selection. RNA, 11, 1701-1709. (Pubitemid 41505544)
    • (2005) RNA , vol.11 , Issue.11 , pp. 1701-1709
    • Legiewicz, M.1    Lozupone, C.2    Knight, R.3    Yarus, M.4
  • 17
    • 0033102314 scopus 로고    scopus 로고
    • A small catalytic RNA motif with Diels-Alderase activity
    • DOI 10.1016/S1074-5521(99)89008-5
    • Seelig, B. and Jäschke, A. (1999) A small catalytic RNA motif with Diels-Alderase activity. Chem. Biol., 6, 167-176. (Pubitemid 29363152)
    • (1999) Chemistry and Biology , vol.6 , Issue.3 , pp. 167-176
    • Seelig, B.1    Jaschke, A.2
  • 19
    • 33746819264 scopus 로고    scopus 로고
    • In vitro selection using a dual RNA library that allows primerless selection
    • Jarosch, F., Buchner, K. and Klussmann, S. (2006) In vitro selection using a dual RNA library that allows primerless selection. Nucleic Acids Res., 34, e86.
    • (2006) Nucleic Acids Res. , vol.34
    • Jarosch, F.1    Buchner, K.2    Klussmann, S.3
  • 20
    • 16544373958 scopus 로고    scopus 로고
    • Selection of genomic sequences that bind tightly to Ff gene 5 protein: Primer-free genomic SELEX
    • Wen, J.-D. and Gray, D.M. (2004) Selection of genomic sequences that bind tightly to Ff gene 5 protein: primer-free genomic SELEX. Nucleic Acids Res., 32, e182.
    • (2004) Nucleic Acids Res. , vol.32
    • Wen, J.-D.1    Gray, D.M.2
  • 21
    • 41849128549 scopus 로고    scopus 로고
    • Minimal primer and primer-free SELEX protocols for selection of aptamers from random DNA libraries
    • DOI 10.2144/000112689
    • Pan, W., Xin, P. and Clawson, G.A. (2008) Minimal primer and primer-free SELEX protocols for selection of aptamers from random DNA libraries. Biotechniques, 44, 351-360. (Pubitemid 351498188)
    • (2008) BioTechniques , vol.44 , Issue.3 , pp. 351-360
    • Pan, W.1    Xin, P.2    Clawson, G.A.3
  • 22
    • 0038204473 scopus 로고    scopus 로고
    • Stereospecific syntheses of 3'-deuterated pyrimidine nucleosides and their site-specific incorporation into DNA
    • DOI 10.1021/ol034102g
    • Chirakul, P. and Sigurdsson, S.T. (2003) Stereospecific syntheses of 30-deuterated pyrimidine nucleosides and their site-specific incorporation into DNA. Org. Lett., 5, 917-919. (Pubitemid 37130649)
    • (2003) Organic Letters , vol.5 , Issue.6 , pp. 917-919
    • Chirakul, P.1    Sigurdsson, S.Th.2
  • 23
    • 0037123284 scopus 로고    scopus 로고
    • Low-temperature photosensitized oxidation of a guanosine derivative and formation of an imidazole ring-opened product
    • DOI 10.1021/ja011696e
    • Sheu, C., Kang, P., Khan, S. and Foote, C.S. (2002) Low-temperature photosensitized oxidation of a guanosine derivative and formation of an imidazole ring-opened product. J. Am. Chem. Soc., 124, 3905-3913. (Pubitemid 34310905)
    • (2002) Journal of the American Chemical Society , vol.124 , Issue.15 , pp. 3905-3913
    • Sheu, C.1    Kang, P.2    Khan, S.3    Foote, C.S.4
  • 24
    • 37049104506 scopus 로고
    • The protection of thymine and guanine residues in oligodeoxyribonucleotide synthesis
    • Reese, C.B. and Skone, P.A. (1984) The protection of thymine and guanine residues in oligodeoxyribonucleotide synthesis. J. Chem. Soc., Perkin Trans, 1, 1263-1271.
    • (1984) J. Chem. Soc. Perkin Trans , vol.1 , pp. 1263-1271
    • Reese, C.B.1    Skone, P.A.2
  • 25
    • 0001599016 scopus 로고
    • Synthesis of DNA containing modified bases by post-synthetic substitution. Synthesis of oligomers containing 4-substituted thymine: O4-alkylthymine, 5-methylcytosine, N4-dimethylamino-5-methylcytosine, and 4-thiothymine
    • Xu, Y.Z., Zheng, Q. and Swann, P.F. (1992) Synthesis of DNA containing modified bases by post-synthetic substitution. Synthesis of oligomers containing 4-substituted thymine: O4-alkylthymine, 5-methylcytosine, N4-dimethylamino-5- methylcytosine, and 4-thiothymine. J. Org. Chem., 57, 3839-3845.
    • (1992) J. Org. Chem. , vol.57 , pp. 3839-3845
    • Xu, Y.Z.1    Zheng, Q.2    Swann, P.F.3
  • 26
    • 0025650326 scopus 로고
    • Synthesis of functionally tethered oligodeoxynucleotides by the convertible nucleoside approach
    • MacMillan, A.M. and Verdine, G.L. (1990) Synthesis of functionally tethered oligodeoxynucleotides by the convertible nucleoside approach. J. Org. Chem., 55, 5931-5933.
    • (1990) J. Org. Chem. , vol.55 , pp. 5931-5933
    • MacMillan, A.M.1    Verdine, G.L.2
  • 27
    • 46549100152 scopus 로고
    • Synthèse d'oligonucléotides liés de facon covalente àun support solide
    • Pochet, S., Huynh-Dinh, T. and Igolen, J. (1985) Synthèse d'oligonucléotides liés de facon covalente àun support solide. Tetrahedron Lett., 26, 627-630.
    • (1985) Tetrahedron Lett. , vol.26 , pp. 627-630
    • Pochet, S.1    Huynh-Dinh, T.2    Igolen, J.3
  • 29
    • 70349975681 scopus 로고    scopus 로고
    • Allylic amination by a DNA-diene-iridium(I) hybrid catalyst. Angew
    • Fournier, P., Fiammengo, R. and Jäschke, A. (2009) Allylic amination by a DNA-diene-iridium(I) hybrid catalyst. Angew. Chem. Int. Ed., 48, 4426-4429.
    • (2009) Chem. Int. Ed. , vol.48 , pp. 4426-4429
    • Fournier, P.1    Fiammengo, R.2    Jäschke, A.3
  • 30
    • 0000577984 scopus 로고    scopus 로고
    • The "one-bead-onecompound" combinatorial library method
    • Lam, K.S., Lebl, M. and Krchnak, V. (1997) The "one-bead- onecompound" combinatorial library method. Chem. Rev., 97, 411-448.
    • (1997) Chem. Rev. , vol.97 , pp. 411-448
    • Lam, K.S.1    Lebl, M.2    Krchnak, V.3
  • 32
    • 67650654679 scopus 로고    scopus 로고
    • On-bead screening of combinatorial libraries: Reduction of nonspecific binding by decreasing surface ligand density
    • Chen, X., Tan, P.H., Zhang, Y. and Pei, D. (2009) On-bead screening of combinatorial libraries: reduction of nonspecific binding by decreasing surface ligand density. J. Comb. Chem., 11, 604-611.
    • (2009) J. Comb. Chem. , vol.11 , pp. 604-611
    • Chen, X.1    Tan, P.H.2    Zhang, Y.3    Pei, D.4
  • 33
    • 0001809323 scopus 로고    scopus 로고
    • Single-bead fluorescence microspectroscopy: Detection of self-quenching in fluorescence-labeled resin beads
    • Yan, B., Martin, P.C. and Lee, J. (1998) Single-bead fluorescence microspectroscopy: detection of self-quenching in fluorescence-labeled resin beads. J. Comb. Chem., 1, 78-81.
    • (1998) J. Comb. Chem. , vol.1 , pp. 78-81
    • Yan, B.1    Martin, P.C.2    Lee, J.3
  • 34
    • 31144435547 scopus 로고    scopus 로고
    • Identification of a 14mer RNA that recognizes and binds flavin mononucleotide with high affinity
    • DOI 10.1093/nar/gki992
    • Anderson, P.C. and Mecozzi, S. (2005) Identification of a 14mer RNA that recognizes and binds flavin mononucleotide with high affinity. Nucleic Acids Res., 33, 6992-6999. (Pubitemid 43125068)
    • (2005) Nucleic Acids Research , vol.33 , Issue.22 , pp. 6992-6999
    • Anderson, P.C.1    Mecozzi, S.2
  • 35
    • 17644381209 scopus 로고    scopus 로고
    • Unusually short RNA sequences: Design of a 13-mer RNA that selectively binds and recognizes theophylline
    • DOI 10.1021/ja0432463
    • Anderson, P.C. and Mecozzi, S. (2005) Unusually short RNA sequences: design of a 13-mer RNA that selectively binds and recognizes theophylline. J. Am. Chem. Soc., 127, 5290-5291. (Pubitemid 40569819)
    • (2005) Journal of the American Chemical Society , vol.127 , Issue.15 , pp. 5290-5291
    • Anderson, P.C.1    Mecozzi, S.2
  • 36
    • 77949497062 scopus 로고    scopus 로고
    • Multiple translational products from a five-nucleotide ribozyme
    • Turk, R.M., Chumachenko, N.V. and Yarus, M. (2010) Multiple translational products from a five-nucleotide ribozyme. Proc. Natl. Acad. Sci., 107, 4585-4589.
    • (2010) Proc. Natl Acad. Sci. , vol.107 , pp. 4585-4589
    • Turk, R.M.1    Chumachenko, N.V.2    Yarus, M.3
  • 39
    • 37349130959 scopus 로고    scopus 로고
    • Identification of microRNAs and other small regulatory RNAs using cDNA library sequencing
    • DOI 10.1016/j.ymeth.2007.09.009, PII S1046202307001752, MicroRNAs: Part B
    • Hafner, M., Landgraf, P., Ludwig, J., Rice, A., Ojo, T., Lin, C., Holoch, D., Lim, C. and Tuschl, T. (2008) Identification of microRNAs and other small regulatory RNAs using cDNA library sequencing. Methods, 44, 3-12. (Pubitemid 350297985)
    • (2008) Methods , vol.44 , Issue.1 , pp. 3-12
    • Hafner, M.1    Landgraf, P.2    Ludwig, J.3    Rice, A.4    Ojo, T.5    Lin, C.6    Holoch, D.7    Lim, C.8    Tuschl, T.9
  • 40
    • 0035955361 scopus 로고    scopus 로고
    • An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
    • DOI 10.1126/science.1065062
    • Lau, N.C., Lim, L.P., Weinstein, E.G. and Bartel, D.P. (2001) An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science, 294, 858-862. (Pubitemid 33032104)
    • (2001) Science , vol.294 , Issue.5543 , pp. 858-862
    • Lau, N.C.1    Lim, L.P.2    Weinstein, E.G.3    Bartel, D.P.4
  • 41
    • 0036899930 scopus 로고    scopus 로고
    • RNomics: Identification and function of small, non-messenger RNAs
    • DOI 10.1016/S1367-5931(02)00397-6
    • Hüttenhofer, A., Brosius, J. and Bachellerie, J.-P. (2002) RNomics: identification and function of small, non-messenger RNAs. Curr. Opin. Chem. Biol., 6, 835-843. (Pubitemid 35449345)
    • (2002) Current Opinion in Chemical Biology , vol.6 , Issue.6 , pp. 835-843
    • Huttenhofer, A.1    Brosius, J.2    Bachellerie, J.-P.3
  • 42
    • 0037119284 scopus 로고    scopus 로고
    • Enzyme accessibility and solid supports: Which molecular weight enzymes can be used on solid supports? An investigation using confocal raman microscopy
    • DOI 10.1002/1521-3765(20020816)8:16<3769::AID-CHEM3769>3.0.CO;2-V
    • Kress, J., Zanaletti, R., Amour, A., Ladlow, M., Frey, J.G. and Bradley, M. (2002) Enzyme accessibility and solid supports: Which molecular weight enzymes can be used on solid supports? An investigation using confocal Raman microscopy. Chem. Eur. J., 8, 3769-3772. (Pubitemid 34951462)
    • (2002) Chemistry - A European Journal , vol.8 , Issue.16 , pp. 3769-3772
    • Kress, J.1    Zanaletti, R.2    Amour, A.3    Ladlow, M.4    Frey, J.G.5    Bradley, M.6
  • 43
    • 0026059558 scopus 로고
    • Nonradioactive labeling of oligonucleotides in vitro with the hapten digoxigenin by tailing with terminal transferase
    • Schmitz, G.G., Walter, T., Seibl, R. and Kessler, C. (1991) Nonradioactive labeling of oligonucleotides in vitro with the hapten digoxigenin by tailing with terminal transferase. Anal. Biochem., 192, 222-231.
    • (1991) Anal. Biochem. , vol.192 , pp. 222-231
    • Schmitz, G.G.1    Walter, T.2    Seibl, R.3    Kessler, C.4
  • 44
    • 0029773520 scopus 로고    scopus 로고
    • Substrate properties of fluorescent ribonucleotides in the terminal transferase-catalyzed labeling of DNA sequencing primers
    • Igloi, G.L. (1996) Substrate properties of fluorescent ribonucleotides in the terminal transferase-catalyzed labeling of DNA sequencing primers. Biotechniques, 21, 1084-1092. (Pubitemid 26422016)
    • (1996) BioTechniques , vol.21 , Issue.6 , pp. 1084-1092
    • Igloi, G.L.1
  • 45
    • 0031915525 scopus 로고    scopus 로고
    • Tailing and 3'-end labeling of RNA with yeast poly(A) polymerase and various nucleotides
    • Martin, G. and Keller, W. (1998) Tailing and 30-end labeling of RNA with yeast poly(A) polymerase and various nucleotides. RNA, 4, 226-230. (Pubitemid 28082296)
    • (1998) RNA , vol.4 , Issue.2 , pp. 226-230
    • Martin, G.1    Keller, W.2
  • 46
    • 78650694123 scopus 로고    scopus 로고
    • Click chemistry for rapid labeling and ligation of RNA
    • Paredes, E. and Das, S.R. (2011) Click chemistry for rapid labeling and ligation of RNA. Chembiochem, 12, 125-131.
    • (2011) Chembiochem , vol.12 , pp. 125-131
    • Paredes, E.1    Das, S.R.2
  • 47
    • 1642618120 scopus 로고    scopus 로고
    • Arrayed primer extension: Solid-phase four-color DNA resequencing and mutation detection technology
    • DOI 10.1089/109065700316408
    • Kurg, A., Tonisson, N., Georgiou, I., Shumaker, J., Tollett, J. and Metspalu, A. (2000) Arrayed primer extension: Solid-phase four-color DNA resequencing and mutation detection technology. Genet. Test., 4, 1-7. (Pubitemid 30217734)
    • (2000) Genetic Testing , vol.4 , Issue.1 , pp. 1-7
    • Kurg, A.1    Tonisson, N.2    Georgiou, I.3    Shumaker, J.4    Tollett, J.5    Metspalu, A.6
  • 48
    • 56649086655 scopus 로고    scopus 로고
    • Arrayed primer extension on in situ synthesized 50-> 30 oligonucleotides in microchannels
    • Pullat, J., Kusnezow, W., Jaakson, K., Beier, M., Hoheisel, J.D. and Metspalu, A. (2008) Arrayed primer extension on in situ synthesized 50-> 30 oligonucleotides in microchannels. New Biotechnol., 25, 133-141.
    • (2008) New Biotechnol. , vol.25 , pp. 133-141
    • Pullat, J.1    Kusnezow, W.2    Jaakson, K.3    Beier, M.4    Hoheisel, J.D.5    Metspalu, A.6
  • 49
    • 31344476038 scopus 로고    scopus 로고
    • Whole-genome genotyping with the single-base extension assay
    • DOI 10.1038/nmeth842, PII N842
    • Steemers, F.J., Chang, W., Lee, G., Barker, D.L., Shen, R. and Gunderson, K.L. (2006) Whole-genome genotyping with the single-base extension assay. Nat. Methods, 3, 31-33. (Pubitemid 43135346)
    • (2006) Nature Methods , vol.3 , Issue.1 , pp. 31-33
    • Steemers, F.J.1    Chang, W.2    Lee, G.3    Barker, D.L.4    Shen, R.5    Gunderson, K.L.6
  • 51
    • 53649106195 scopus 로고    scopus 로고
    • Next-generation DNA sequencing
    • Shendure, J. and Ji, H. (2008) Next-generation DNA sequencing. Nat. Biotechnol., 26, 1135-1145.
    • (2008) Nat. Biotechnol. , vol.26 , pp. 1135-1145
    • Shendure, J.1    Ji, H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.