Long-term effects of autologous bone marrow stem cell treatment in acute myocardial infarction: Factors that may influence outcomes

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Clifford, David M ^a,b,e   Fisher, Sheila A ^a   Brunskill, Susan J ^a   Doree, Carolyn ^a   Mathur, Anthony ^c   Clarke, Mike J ^d   Watt, Suzanne M ^a,b   Martin Rendon, Enca ^a,b  

^a JOHN RADCLIFFE HOSPITAL   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^d QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^e UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE HEART INFARCTION; ARTICLE; AUTOLOGOUS BONE MARROW TRANSPLANTATION; CELL HETEROGENEITY; DISEASE SEVERITY; EFFECT SIZE; FOLLOW UP; HEART DISEASE; HEART LEFT VENTRICLE EJECTION FRACTION; HUMAN; LONG TERM CARE; META ANALYSIS; MORBIDITY; MORTALITY; OUTCOME ASSESSMENT; PATIENT SELECTION; QUALITY CONTROL; RISK ASSESSMENT; SYSTEMATIC REVIEW; TREATMENT DURATION; TREATMENT RESPONSE; ACUTE DISEASE; AUTOTRANSPLANTATION; HEART INFARCTION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; TIME; TREATMENT OUTCOME;

ACUTE DISEASE; FOLLOW-UP STUDIES; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; MYOCARDIAL INFARCTION; TIME; TRANSPLANTATION, AUTOLOGOUS; TREATMENT OUTCOME;

EID: 84861362004     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0037373     Document Type: Article

References (50)

1. Velagaleti RS, Pencina MJ, Murabito JM, Wang TJ, Parikh NI, et al. (2008) Long-term trends in the incidence of heart failure after myocardial infarction. Circulation 118: 2057-2062.
2. McMurray JJ, Pfeffer MA, (2005) Heart failure. Lancet 365: 1877-1889.
3. Wollert KC, Drexler H, (2010) Cell therapy for the treatment of coronary heart disease: a critical appraisal. Nat Rev Cardiol 7: 204-215.
4. Clifford DM, Fisher SA, Brunskill SJ, Doree C, Mathur A, et al. (2012) Stem cell treatment for acute myocardial infarction. Cochrane Database Syst Rev 2: CD006536.
5. Wollert KC, Meyer GP, Lotz J, Ringes-Lichtenberg S, Lippolt P, et al. (2004) Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial. Lancet 364: 141-148.
6. Chen SL, Fang WW, Ye F, Liu YH, Qian J, et al. (2004) Effect on left ventricular function of intracoronary transplantation of autologous bone marrow mesenchymal stem cell in patients with acute myocardial infarction. Am J Cardiol 94: 92-95.
7. Janssens S, Dubois C, Bogaert J, Theunissen K, Deroose C, et al. (2006) Autologous bone marrow-derived stem-cell transfer in patients with ST-segment elevation myocardial infarction: double-blind, randomised controlled trial. Lancet 367: 113-121.
8. Lunde K, Solheim S, Aakhus S, Arnesen H, Abdelnoor M, et al. (2006) Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction. N Engl J Med 355: 1199-1209.
9. Schachinger V, Erbs S, Elsasser A, Haberbosch W, Hambrecht R, et al. (2006) Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction. N Engl J Med 355: 1210-1221.
10. Martin-Rendon E, Brunskill SJ, Hyde CJ, Stanworth SJ, Mathur A, et al. (2008) Autologous bone marrow stem cells to treat acute myocardial infarction: a systematic review. Eur Heart J 29: 1807-1818.
11. Janssens SP, (2011) Cardiac bone marrow cell therapy: the proof of the pudding remains in the eating. Eur Heart J 32: 1697-1700.
12. Abdel-Latif A, Bolli R, Tleyjeh IM, Montori VM, Perin EC, et al. (2007) Adult bone marrow-derived cells for cardiac repair: a systematic review and meta-analysis. Arch Intern Med 167: 989-997.
13. Lipinski MJ, Biondi-Zoccai GG, Abbate A, Khianey R, Sheiban I, et al. (2007) Impact of intracoronary cell therapy on left ventricular function in the setting of acute myocardial infarction: a collaborative systematic review and meta-analysis of controlled clinical trials. J Am Coll Cardiol 50: 1761-1767.
14. Ioannidis JP, Trikalinos TA, (2005) Early extreme contradictory estimates may appear in published research: the Proteus phenomenon in molecular genetics research and randomized trials. J Clin Epidemiol 58: 543-549.
15. Hopewell S, Clarke M, Stewart L, Tierney J, (2007) Time to publication for results of clinical trials. Cochrane Database Syst Rev.
16. Trikalinos TA, Churchill R, Ferri M, Leucht S, Tuunainen A, et al. (2004) Effect sizes in cumulative meta-analyses of mental health randomized trials evolved over time. J Clin Epidemiol 57: 1124-1130.
17. Robinson KA, Dickersin K, (2002) Development of a highly sensitive search strategy for the retrieval of reports of controlled trials using PubMed. Int J Epidemiol 31: 150-153.
18. Higgins J, Green S, (2008) Cochrane Handbook for Systematic Reviews of Interventions 5.0.0; Higgins J, Green S, editors. Chichester, UK John Wiley & Sons Ltd.
19. Higgins JP, Thompson SG, (2002) Quantifying heterogeneity in a meta-analysis. Stat Med 21: 1539-1558.
20. Hopewell S, Loudon K, Clarke MJ, Oxman AD, Dickersin K, (2009) Publication bias in clinical trials due to statistical significance or direction of trial results. Cochrane Database Syst Rev.
21. Fernandez-Pereira C, Vigo C, Bataglia S, De la Hoz R, Vetulli H, et al. (2006) Autologous bone marrow stem cell transplant after myocardial infarction. In-hospital and long-term follow-up results of the randomised argentina trial (STAR AMI). Eur Heart J August.
22. Zhukova NS, Staroverov, II, Stukalova OV, Samoleinko LE, Romanov Iu A, et al. (2009) An experience of the use of stem cells in the treatment of patients with myocardial infarction and low ejection fraction. Kardiologiia 49: 19-24.
23. Meyer GP, Wollert KC, Lotz J, Steffens J, Lippolt P, et al. (2006) Intracoronary bone marrow cell transfer after myocardial infarction: eighteen months' follow-up data from the randomized, controlled BOOST (BOne marrOw transfer to enhance ST-elevation infarct regeneration) trial. Circulation 113: 1287-1294.
24. Nogueira FB, Silva SA, Haddad AF, Peixoto CM, Carvalho RM, et al. (2009) Systolic function of patients with myocardial infarction undergoing autologous bone marrow transplantation. Arq Bras Cardiol 93: 374-379, 367-372.
25. Hirsch A, Nijveldt R, van der Vleuten PA, Tijssen JG, van der Giessen WJ, et al. (2011) Intracoronary infusion of mononuclear cells from bone marrow or peripheral blood compared with standard therapy in patients after acute myocardial infarction treated by primary percutaneous coronary intervention: results of the randomized controlled HEBE trial. Eur Heart J 32: 1736-1747.
26. Roncalli J, Mouquet F, Piot C, Trochu JN, Le Corvoisier P, et al. (2011) Intracoronary autologous mononucleated bone marrow cell infusion for acute myocardial infarction: results of the randomized multicenter BONAMI trial. Eur Heart J 32: 1748-1757.
27. Tendera M, Wojakowski W, Ruzyllo W, Chojnowska L, Kepka C, et al. (2009) Intracoronary infusion of bone marrow-derived selected CD34+CXCR4+ cells and non-selected mononuclear cells in patients with acute STEMI and reduced left ventricular ejection fraction: results of randomized, multicentre Myocardial Regeneration by Intracoronary Infusion of Selected Population of Stem Cells in Acute Myocardial Infarction (REGENT) Trial. Eur Heart J 30: 1313-1321.
28. Grajek S, Popiel M, Gil L, Breborowicz P, Lesiak M, et al. (2010) Influence of bone marrow stem cells on left ventricle perfusion and ejection fraction in patients with acute myocardial infarction of anterior wall: randomized clinical trial: Impact of bone marrow stem cell intracoronary infusion on improvement of microcirculation. Eur Heart J 31: 691-702.
29. Karpov RS, Popov SV, Markov VA, Suslova TE, Ryabov VV, et al. (2005) Autologous mononuclear bone marrow cells during reparative regeneratrion after acute myocardial infarction. Bull Exp Biol Med 140: 640-643.
30. Piepoli MF, Vallisa D, Arbasi M, Cavanna L, Cerri L, et al. (2010) Bone marrow cell transplantation improves cardiac, autonomic, and functional indexes in acute anterior myocardial infarction patients (Cardiac Study). Eur J Heart Fail 12: 172-180.
31. Li ZQ, Zhang M, Jing YZ, Zhang WW, Liu Y, et al. (2007) The clinical study of autologous peripheral blood stem cell transplantation by intracoronary infusion in patients with acute myocardial infarction (AMI). Int J Cardiol 115: 52-56.
32. Arnesen H, Lunde K, Aakhus S, Forfang K, (2007) Cell therapy in myocardial infarction. Lancet 369: 2142-2143.
33. Kumar A, Galeb S, Djulbegovic B Treatment of patients with multiple myeloma: an overview of systematic reviews. Acta Haematol 125: 8-22.
34. Montalescot G, Barragan P, Wittenberg O, Ecollan P, Elhadad S, et al. (2001) Platelet glycoprotein IIb/IIIa inhibition with coronary stenting for acute myocardial infarction. N Engl J Med 344: 1895-1903.
35. Stone GW, Grines CL, Cox DA, Garcia E, Tcheng JE, et al. (2002) Comparison of angioplasty with stenting, with or without abciximab, in acute myocardial infarction. N Engl J Med 346: 957-966.
36. Halkin A, Singh M, Nikolsky E, Grines CL, Tcheng JE, et al. (2005) Prediction of mortality after primary percutaneous coronary intervention for acute myocardial infarction: the CADILLAC risk score. J Am Coll Cardiol 45: 1397-1405.
37. Simoons ML, Vos J, Tijssen JG, Vermeer F, Verheugt FW, et al. (1989) Long-term benefit of early thrombolytic therapy in patients with acute myocardial infarction: 5 year follow-up of a trial conducted by the Interuniversity Cardiology Institute of The Netherlands. J Am Coll Cardiol 14: 1609-1615.
38. Assmus B, Rolf A, Erbs S, Elsasser A, Haberbosch W, et al. (2010) Clinical outcome 2 years after intracoronary administration of bone marrow-derived progenitor cells in acute myocardial infarction. Circ Heart Fail 3: 89-96.
39. Brunskill SJ, Hyde CJ, Doree CJ, Watt SM, Martin-Rendon E, (2009) Route of delivery and baseline left ventricular ejection fraction, key factors of bone-marrow-derived cell therapy for ischaemic heart disease. Eur J Heart Fail 11: 887-896.
40. Schachinger V, Aicher A, Dobert N, Rover R, Diener J, et al. (2008) Pilot trial on determinants of progenitor cell recruitment to the infarcted human myocardium. Circulation 118: 1425-1432.
41. Gnecchi M, Zhang Z, Ni A, Dzau VJ, (2008) Paracrine mechanisms in adult stem cell signaling and therapy. Circ Res 103: 1204-1219.
42. Traverse JH, Henry TD, Vaughan DE, Ellis SG, Pepine CJ, et al. (2009) Rationale and design for TIME: A phase II, randomized, double-blind, placebo-controlled pilot trial evaluating the safety and effect of timing of administration of bone marrow mononuclear cells after acute myocardial infarction. Am Heart J 158: 356-363.
43. Traverse JH, Henry TD, Vaughan DE, Ellis SG, Pepine CJ, et al. (2010) LateTIME: a phase-II, randomized, double-blinded, placebo-controlled, pilot trial evaluating the safety and effect of administration of bone marrow mononuclear cells 2 to 3 weeks after acute myocardial infarction. Tex Heart Inst J 37: 412-420.
44. Meluzin J, Janousek S, Mayer J, Groch L, Hornacek I, et al. (2008) Three-, 6-, and 12-month results of autologous transplantation of mononuclear bone marrow cells in patients with acute myocardial infarction. Int J Cardiol 128: 185-192.
45. Yao K, Huang R, Sun A, Qian J, Liu X, et al. (2009) Repeated autologous bone marrow mononuclear cell therapy in patients with large myocardial infarction. Eur J Heart Fail 11: 691-698.
46. Quyyumi AA, Waller EK, Murrow J, Esteves F, Galt J, et al. (2011) CD34(+) cell infusion after ST elevation myocardial infarction is associated with improved perfusion and is dose dependent. Am Heart J 161: 98-105.
47. Cao F, Sun D, Li C, Narsinh K, Zhao L, et al. (2009) Long-term myocardial functional improvement after autologous bone marrow mononuclear cells transplantation in patients with ST-segment elevation myocardial infarction: 4 years follow-up. Eur Heart J 30: 1986-1994.
48. Jin B, Yang Y, Shi H, Luo X, Li Y, et al. (2008) Autologous intracoronary mononuclear bone marrow cell transplantation for acute anterior myocardial infarction: Outcomes after 12-month follow-up. Journal of Clinical Rehabilitative Tissue Engineering Research 12: 2267-2271.
49. Suarez de Lezo J, Herrera CP, M, Romero M, Pavlovic D, Segura J, et al. (2007) Tratamiento regenerativo en pacientes con infarto agudo anterior revascularizado y funcion ventricular deprimida. Rev Esp Cardiol 60: 357-365.
50. Penicka M, Horak J, Kobylka P, Pytlik R, Kozak T, et al. (2007) Intracoronary injection of autologous bone marrow-derived mononuclear cells in patients with large anterior acute myocardial infarction: a prematurely terminated randomized study. J Am Coll Cardiol 49: 2373-2374.