SOX2 hypomorphism disrupts development of the prechordal floor and optic cup

Mechanisms of Development

Volumn 129, Issue 1-4, 2012, Pages 1-12

  Langer, Lee ^a   Taranova, Olena ^a,b   Sulik, Kathleen ^a,b   Pevny, Larysa ^a,b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Optic cup; Optic stalk; Patterning; Prechordal floor; Shh; Sox2

Indexed keywords

TRANSCRIPTION FACTOR SOX2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLOBOMA; CONTROLLED STUDY; DIENCEPHALON; EMBRYO; EMBRYO PATTERN FORMATION; ENZYME ACTIVITY; ENZYME REGULATION; EYE; FEMALE; GERM LINE; GROWTH RETARDATION; HAPLOINSUFFICIENCY; HYPOTHALAMUS; MALE; MOUSE; NONHUMAN; OPTIC DISK CUP; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION;

ANIMALS; DIENCEPHALON; DISEASE MODELS, ANIMAL; EMBRYO, MAMMALIAN; EYE ABNORMALITIES; HAPLOINSUFFICIENCY; HUMANS; HYPOTHALAMUS; MICE; MICE, TRANSGENIC; MICROSCOPY, ELECTRON, SCANNING; ORGAN SPECIFICITY; SOXB1 TRANSCRIPTION FACTORS;

MUS;

EID: 84861345792     PISSN: 09254773     EISSN: 18726356     Source Type: Journal    
DOI: 10.1016/j.mod.2012.04.001     Document Type: Article

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