Reduced metal ion concentrations in atherosclerotic plaques from subjects with Type 2 diabetes mellitus

Atherosclerosis

Volumn 222, Issue 2, 2012, Pages 512-518

  Stadler, Nadina ^a,b   Heeneman, Sylvia ^b   Vöö, Stefan ^b   Stanley, Naomi ^a   Giles, Gregory I ^c   Gang, Bevan P ^c   Croft, Kevin D ^d   Mori, Trevor A ^d   Vacata, Vladimir ^e   Daemen, Mat J A P ^b,f   Waltenberger, Johannes ^b,g   Davies, Michael J ^a,h  

^a HEART RESEARCH INSTITUTE   (Australia)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c UNIVERSITY OF OTAGO   (New Zealand)

^d UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^e Medizinisches Versorgungszentrum   (Germany)

^f ACADEMIC MEDICAL CENTER   (Netherlands)

^g UNIVERSITY OF MÜNSTER   (Germany)

^h University of Sydney   (Australia)

Author keywords

Calcium; Iron; Lipid oxidation; Metal ions; Oxidation; Protein oxidation; Type 2 diabetes; Zinc

Indexed keywords

CALCIUM; COPPER; GLUCOSE; IRON; ISOPROSTANE DERIVATIVE; TYROSINE; ZINC;

ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CALCIUM BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; COPPER BLOOD LEVEL; DIABETIC PATIENT; DIET RESTRICTION; DISEASE EXACERBATION; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; HUMAN TISSUE; HYPERGLYCEMIA; IRON BLOOD LEVEL; LIPID OXIDATION; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OXIDATIVE STRESS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RISK ASSESSMENT; SEX DIFFERENCE; X RAY FLUORESCENCE; ZINC BLOOD LEVEL;

AUTOPSY; CALCIUM; CAROTID ARTERIES; CAROTID ARTERY DISEASES; COPPER; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; DOWN-REGULATION; ELECTRON SPIN RESONANCE SPECTROSCOPY; F2-ISOPROSTANES; FEMALE; HUMANS; IRON; LIPIDS; MALE; MASS SPECTROMETRY; METALS; MICROSCOPY, FLUORESCENCE; NETHERLANDS; OXIDATION-REDUCTION; PLAQUE, ATHEROSCLEROTIC; ZINC;

EID: 84861343587     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2012.03.015     Document Type: Article

References (34)

1. Halliwell B., Gutteridge J.M.C. Free radicals in biology and medicine 2007, Oxford University Press, Oxford, p. 1-704.
2. Stocker R., Keaney J.F. Role of oxidative modifications in atherosclerosis. Physiol Rev 2004, 84:1381-1478.
3. Stadler N., Lindner R.A., Davies M.J. Direct detection and quantification of transition metal ions in human atherosclerotic plaques: evidence for the presence of elevated levels of iron and copper. Arterioscler Thromb Vasc Biol 2004, 24:949-954.
4. Stanley N., Stadler N., Woods A.A., et al. Concentrations of iron correlate with the extent of protein, but not lipid, oxidation in advanced human atherosclerotic lesions. Free Radic Biol Med 2006, 40:1636-1643.
5. Raman S.V., Winner M.W., Tran T., et al. In vivo atherosclerotic plaque characterization using magnetic susceptibility distinguishes symptom-producing plaques. JACC Cardiovasc Imaging 2008, 1:49-57.
6. Yuan X.M., Li W. Iron involvement in multiple signaling pathways of atherosclerosis: a revisited hypothesis. Curr Med Chem 2008, 15:2157-2172.
7. Sullivan J.L. Iron and the sex difference in heart disease risk. Lancet 1981, 1:1293-1294.
8. Danesh J., Appleby P. Coronary heart disease and iron status: meta-analyses of prospective studies. Circulation 1999, 99:852-854.
9. Swaminathan S., Fonseca V.A., Alam M.G., et al. The role of iron in diabetes and its complications. Diabetes Care 2007, 30:1926-1933.
10. Sullivan J.L. Iron in arterial plaque: modifiable risk factor for atherosclerosis. Biochim Biophys Acta 2009, 1790:718-723.
11. Rajpathak S.N., Crandall J.P., Wylie-Rosett J., et al. The role of iron in type 2 diabetes in humans. Biochim Biophys Acta 2009, 1790:671-681.
12. Pennathur S., Heinecke J.W. Mechanisms for oxidative stress in diabetic cardiovascular disease. Antioxid Redox Signal 2007, 9:955-969.
13. Hayden M.R., Tyagi S.C. Is type 2 diabetes mellitus a vascular disease (atheroscleropathy) with hyperglycemia a late manifestation? The role of NOS, NO, and redox stress. Cardiovasc Diabetol 2003, 2:2.
14. Zacharski L.R., Chow B.K., Howes P.S., et al. Implementation of an iron reduction protocol in patients with peripheral vascular disease: VA cooperative study no. 410: the Iron (Fe) and Atherosclerosis Study (FeAST). Am Heart J 2004, 148:386-392.
15. Eshed I., Elis A., Lishner M. Plasma ferritin and type 2 diabetes mellitus: a critical review. Endocr Res 2001, 27:91-97.
16. Freixenet N., Vilardell C., Llaurado G., et al. Men with hyperferritinemia and diabetes in the Mediterranean area do not have a higher iron overload than those without diabetes. Diabetes Res Clin Pract 2011, 91:e33-e36.
17. Hernandez C., Lecube A., Carrera A., et al. Soluble transferrin receptors and ferritin in Type 2 diabetic patients. Diabet Med 2005, 22:97-101.
18. Fernandez-Real J.M., Penarroja G., Castro A., et al. Blood letting in high-ferritin type 2 diabetes: effects on vascular reactivity. Diabetes Care 2002, 25:2249-2255.
19. Virmani R., Kolodgie F.D., Burke A.P., et al. Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions. Arterioscler Thromb Vasc Biol 2000, 20:1262-1275.
20. Stadler N., Stanley N., Heeneman S., et al. Accumulation of zinc in human atherosclerotic lesions correlates with calcium levels but does not protect against protein oxidation. Arterioscler Thromb Vasc Biol 2008, 28:1024-1030.
21. Mori T.A., Croft K.D., Puddey I.B., et al. An improved method for the measurement of urinary and plasma F2-isoprostanes using gas chromatography-mass spectrometry. Anal Biochem 1999, 268:117-125.
22. Vogt S. MAPS: a set of software tools for analysis and visualization of 3D X-ray fluorescence data sets. J Phys IV 2003, 104:635-638.
23. Easter R.N., Qilin C., Lai B., et al. Vascular metallomics: copper in the vasculature. Vasc Med 2010, 15:61-69.
24. Rowe P.A., Kavanagh K., Zhang L., et al. Short-term hyperglycemia increases arterial superoxide production and iron dysregulation in atherosclerotic monkeys. Metabolism 2011.
25. Konijn A.M., Hershko C. Ferritin synthesis in inflammation. I. Pathogenesis of impaired iron release. Br J Haematol 1977, 37:7-16.
26. Blazewicz A., Orlicz-Szczesna G., Prystupa A., et al. Use of ion chromatography for the determination of selected metals in blood serum of patients with type 2 diabetes. J Trace Elem Med Biol 2010, 24:14-19.
27. Liu Q., Sun L., Tan Y., et al. Role of iron deficiency and overload in the pathogenesis of diabetes and diabetic complications. Curr Med Chem 2009, 16:113-129.
28. Chait A., Bornfeldt K.E. Diabetes and atherosclerosis: is there a role for hyperglycemia?. J Lipid Res 2009, 50(Suppl.):S335-S339.
29. Ford E.S., Zhao G., Li C. Pre-diabetes and the risk for cardiovascular disease: a systematic review of the evidence. J Am Coll Cardiol 2010, 55:1310-1317.
30. Kolodgie F.D., Virmani R., Burke A.P., et al. Pathologic assessment of the vulnerable human coronary plaque. Heart 2004, 90:1385-1391.
31. Nicholls S.J., Tuzcu E.M., Kalidindi S., et al. Effect of diabetes on progression of coronary atherosclerosis and arterial remodeling: a pooled analysis of 5 intravascular ultrasound trials. J Am Coll Cardiol 2008, 52:255-262.
32. Lundby-Christensen L., Almdal T.P., Carstensen B., et al. Carotid intima-media thickness in individuals with and without type 2 diabetes: a reproducibility study. Cardiovasc Diabetol 2010, 9:40.
33. Mehta J.L., Rasouli N., Sinha A.K., et al. Oxidative stress in diabetes: a mechanistic overview of its effects on atherogenesis and myocardial dysfunction. Int J Biochem Cell Biol 2006, 38:794-803.
34. Colak E., Majkic-Singh N., Stankovic S., et al. Parameters of antioxidative defense in type 2 diabetic patients with cardiovascular complications. Ann Med 2005, 37:613-620.