Standardized diaper care regimen: A prospective, randomized pilot study on skin barrier function and epidermal IL-1α in newborns

Pediatric Dermatology

Volumn 29, Issue 3, 2012, Pages 270-276

  Garcia Bartels, Natalie ^a   Massoudy, Lida ^a   Scheufele, Ramona ^a   Dietz, Ekkehart ^a   Proquitté, Hans ^a   Wauer, Roland ^a   Bertin, Christiane ^b   Serrano, José ^b   Blume Peytavi, Ulrike ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b JOHNSON AND JOHNSON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1ALPHA;

ARTICLE; BUTTOCK; CLINICAL ARTICLE; CLOTHING; CONTROLLED STUDY; DIAPER; DIAPER DERMATITIS; FEMALE; HUMAN; HYDRATION; MALE; MICROBIAL COLONIZATION; MOISTURE; NEWBORN; PERMEABILITY BARRIER; PH; PILOT STUDY; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SKIN CARE; SKIN WATER LOSS;

BUTTOCKS; DIAPERS, INFANT; EPIDERMIS; FEMALE; HUMANS; HYDROGEN-ION CONCENTRATION; INFANT CARE; INFANT, NEWBORN; INTERLEUKIN-1ALPHA; MALE; PILOT PROJECTS; SKIN CARE; WATER LOSS, INSENSIBLE;

EID: 84861342688     PISSN: 07368046     EISSN: 15251470     Source Type: Journal    
DOI: 10.1111/j.1525-1470.2011.01590.x     Document Type: Article

References (26)

1. Priestley GC, McVittie E, Aldridge RD,. Changes in skin pH after the use of baby wipes. Pediatr Dermatol 1996; 13: 14-17.
2. Andersen PH, Bucher AP, Saeed I, et al., Faecal enzymes: in vivo human skin irritation. Contact Dermatitis 1994; 30: 152-158.
3. Gelmetti C,. Skin cleansing in children. J Eur Acad Dermatol Venereol 2001; 15 (Suppl 1): 12-15.
4. Visscher M, Odio M, Taylor T, et al., Skin care in the NICU patient: effects of wipes versus cloth and water on stratum corneum integrity. Neonatol 2009; 96: 226-234.
5. Nikolovski J, Stamatas GN, Kollias N, et al., Barrier function and water-holding and transport properties of infant stratum corneum are different from adult and continue to develop through the first year of life. J Invest Dermatol 2008; 128: 1728-1736.
6. Garcia Bartels N, Scheufele R, Prosch F, et al., Effect of standardized skin care regimens on neonatal skin barrier function in different body areas. Pediatr Dermatol 2010; 27: 1-8.
7. Garcia Bartels N, Mleczko A, Schink T, et al., Influence of bathing or washing on skin barrier function in newborns during the first four weeks of life. Skin Pharmacol Physiol 2009; 22: 248-257.
8. Hoeger PH, Enzmann CC,. Skin physiology of the neonate and young infant: a prospective study of functional skin parameters during early infancy. Pediatr Dermatol 2002; 19: 256-262.
9. Visscher MO, Chatterjee R, Munson KA, et al., Changes in diapered and nondiapered infant skin over the first month of life. Pediatr Dermatol 2000; 17: 45-51.
10. Yosipovitch G, Maayan-Metzger A, Merlob P, et al., Skin barrier properties in different body areas in neonates. Pediatr 2000; 1: 105-108.
11. Halgunset J, Johnsen H, Kjollesdal AM, et al., Cytokine levels in amniotic fluid and inflammatory changes in the placenta from normal deliveries at term. Eur J Obstet Gynecol Reprod Biol 1994; 56: 153-160.
12. Jiang YJ, Lu B, Crumrine D, et al., IL-1alpha accelerates stratum corneum formation and improves permeability barrier homeostasis during murine fetal development. J Dermatol Sci 2009; 54: 88-98.
13. Perkins MA, Osterhues MA, Farage MA, et al., A noninvasive method to assess skin irritation and compromised skin conditions using simple tape adsorption of molecular markers of inflammation. Skin Res Technol 2001; 7: 227-237.
14. Schatz H, Kligman AM, Manning S, et al., Quantification of dry (xerotic) skin by image-analysis of scales removed by adhesive disks (D-Squames). J Soc Cosmet Chem 1993; 44: 53-63.
15. Lund CH, Osborne JW,. Validity and reliability of the neonatal skin condition score. J Obstet Gynecol Neonatal Nurs 2004; 33: 320-327.
16. R Development Core Team. R: A language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing, editor, 2008.
17. Brunner E, Domhof S, Langer F,. Nonparametric analysis of longitudinal data in factorial experiments. New York: Wiley Interscience, 2002.
18. Visscher MO, Chatterjee R, Munson KA, et al., Development of diaper rash in the newborn. Pediatr Dermatol 2000; 17: 52-57.
19. Pinnagoda J, Tupker RA, Agner T, et al., Guidelines for transepidermal water loss (TEWL) measurement. A report from the Standardization Group of the European Society of Contact Dermatitis. Contact Dermatitis 1990; 22: 164-178.
20. Chiou YB, Blume-Peytavi U,. Stratum corneum maturation. A review of neonatal skin function. Skin Pharmacol Physiol 2004; 17: 57-66.
21. Sato J, Yanai M, Hirao T, et al., Water content and thickness of the stratum corneum contribute to skin surface morphology. Arch Dermatol Res 2000; 292: 412-417.
22. Behne MJ, Barry NP, Hanson KM, et al., Neonatal development of the stratum corneum pH gradient: localization and mechanisms leading to emergence of optimal barrier function. J Invest Dermatol 2003; 120: 998-1006.
23. Fluhr JW, Darlenski R, Angelova-Fischer I, et al., Skin irritation and sensitization: mechanisms and new approaches for risk assessment. 1. Skin irritation. Skin Pharmacol Physiol 2008; 21: 124-135.
24. Fields KS, Nelson T, Powell D,. Contact dermatitis caused by baby wipes. J Am Acad Dermatol 2006; 54 (Suppl 5): 230-232.
25. Walker L, Downe S, Gomez L,. Skin care in the well term newborn: two systematic reviews. Birth 2005; 32: 224-228.
26. Blume-Peytavi U, Cork MJ, Faergemann J, et al., Bathing and cleansing in newborns from day 1 to first year of life: recommendations from a European round table meeting. J Eur Acad Dermatol Venereol 2009; 23: 751-759.