Current smoking differentially affects blood mononuclear cells from patients with crohn's disease and ulcerative colitis: Relevance to its adverse role in the disease

Inflammatory Bowel Diseases

Volumn 18, Issue 6, 2012, Pages 1101-1111

  Bergeron, Vivianne ^a,b   Grondin, Virginie ^a   Rajca, Sylvie ^a   Maubert, Marie Anne ^a   Pigneur, Benedicte ^a   Thomas, Ginette ^a   Trugnan, Germain ^a   Beaugerie, Laurent ^a,b   Cosnes, Jacques ^a,b   Masliah, Joelle ^a   Sokol, Harry ^a,b   Seksik, Philippe ^a,b   Bachelet, Maria ^a  

^a Centre National de la Recherche Scientifique   (France)

^b HÔPITAL SAINT ANTOINE   (France)

Author keywords

blood mononuclear cells; chemokines; cigarette smoke; cytokines; inflammatory bowel disease; oxidative injury

Indexed keywords

CIGARETTE SMOKE; HEAT SHOCK PROTEIN 70; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 23; INTERLEUKIN 8; PROSTAGLANDIN E2;

ADULT; ARTICLE; CELL PROTECTION; CELL VIABILITY; CIGARETTE SMOKING; CONTROLLED STUDY; CROHN DISEASE; CYTOKINE RELEASE; DISEASE EXACERBATION; ENZYME IMMUNOASSAY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MAJOR CLINICAL STUDY; MALE; OXIDATIVE STRESS; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SMOKING; ULCERATIVE COLITIS;

ADULT; BLOOD CELLS; CASE-CONTROL STUDIES; CELL SURVIVAL; CHEMOKINES; COLITIS, ULCERATIVE; CROHN DISEASE; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HSP70 HEAT-SHOCK PROTEINS; HUMANS; LEUKOCYTES, MONONUCLEAR; MALE; SMOKING;

EID: 84861336981     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1002/ibd.21889     Document Type: Article

References (31)

1. Cosnes J, Carbonnel J, Beaugerie L, et al. Effects of cigarette smoking on the long-term course of Crohn's disease. Gastroenterology. 1996; 110: 424-431.
2. Cosnes J,. Tobacco and IBD: relevance in the understanding of diseases mechanisms and clinical practice. Best Practice Res Clin Gastroenterol. 2004; 18: 481-496.
3. Stohs SJ, Bagchi D, Bagchi M,. Toxicity of trace elements in tobacco smoke. Inhalation Toxicol. 1997; 9: 867-890.
4. Zang L, Stone K, Pryor WA,. Detection of free radicals in aqueous extracts of cigarette tar by electron spin resonance. Free Radic Biol Med. 1995; 19: 161-167.
5. Tyndale RF, Sellers EM. Variable cyp2a6-mediated nicotine metabolismn alters smoking behaviour and risk. Drug Metab Dispos. 2001; 29: 548-552.
6. Chen H, Cowan MJ, Hasday JD, et al. Tobacco smoking inhibits expression of proinflammatory cytokines and activation of IL-1R-associated kinase, p38, and NFκB in alveolar macrophages stimulated with TLR2 and TLR4 agonists. J Immunol. 2007; 179: 6097-6106.
7. Sopori M,. Effects of cigarette smoke on the immune system. Nat Rev Immunol. 2002; 2: 372-377.
8. Laan M, Bozinovski S, Anderson GP,. Cigarette smoke inhibits lipopolysaccharide-induced production of inflammatory cytokines by suppressing the activation of activator protein-1 in bronchial epithelial cells. J Immunol. 2004; 173: 4164-4170.
9. Seksik P, Sokol H, Grondin V, et al. Sera from patients with Crohn's disease break bacterial lipopolysaccharide tolerance of human intestinal epithelial cells via MD-2 activity. Innate Immun. 2010; 16: 381-390.
10. Savoye G, Lerebours E,. Toll-like receptor-4 signaling: a possible candidate pathway to support tobacco smoking effects in ulcerative colitis. A J Gastroenterol. 2008; 103: 2947-2948.
11. McGovern D, Powrie F,. The IL23 axis plays a key role in the pathogenesis of IBD. Gut. 2007; 56: 1333-1336.
12. Shale M, Ghosh S,. Beyond TNF, Th1 and Th2 in inflammatory bowel disease. Gut. 2008; 57: 1349-1351.
13. Stolina M, Sharma S, Lin Y, et al. Specific inhibition of cyclooxygenase 2 restores antitumor reactivity by altering the balance of IL-10 and IL-12 synthesis. J Immunol. 2000; 164: 361-370.
14. Polla BS, Kantengwa S, Francois D, et al. Mitochondria are selective targets for the protective effects of heat shock against oxidative injury. Proc Natl Acad Sci U S A. 1996; 93: 6458-6463.
15. Thomas G, Souil E, Richard M-J, et al. Hyperthermia assists survival of astrocytes from oxidative-mediated necrotic cell death. Cell Mol Biol. 2002; 48: 191-198.
16. Lennard-Jones JE,. Classification of inflammatory bowel disease. Scand J Gastroenterol. 1989; 170: 2-6.
17. Silverberg MS, Satsangi J, Ahmad T, et al. Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a Working Party of the 2005 Montreal World Congress of Gastroenterology. Can J Gastroenterol. 2005; 19: 45-43.
18. Pryor WA,. Biological effects of cigarette smoke, wood smoke, and the smoke from plastics: the use of electron spin resonance. Free Radic Biol Med. 1992; 13: 659-676.
19. Grondin V, Seksik P, Dumont S, et al. Regulation of colon cancer cell proliferation by MD-2 activity. Innate Immun. 2011; 17: 414-422.
20. Hurt RD, Dale LC, Fredrickson PA, et al. Nicotine patch therapy for smoking cessation combined with physician advice and nurse follow up: one year outcome and percentage of nicotine replacement. JAMA. 1994; 71: 595-600.
21. Vassallo R, Tamada K, Lau JS, et al. Cigarette smoke extract suppresses human dendritic cell function leading to preferential induction of Th-2 priming. J Immunol. 2005; 175: 2684-2691.
22. McMaster SK, Paul-Clark MJ, Walters M, et al. Cigarette smoke inhibits macrophage sensing of Gram-negative bacteria and lipopolysaccharide: relative roles of nicotine and oxidative stress. Br J Pharmacol. 2008; 153: 536-543.
23. Bouma G, Strober W,. The immunological and genetic basis of inflammatory bowel disease. Nat Rev Immunol. 2003; 3: 521-533.
24. Mahida YR, Wu K, Jewell DP,. 1989. Enhanced production of interleukin-1-beta by mononuclear cells isolated from mucosa with active ulcerative colitis or Crohn's disease. Gut. 1989; 30: 835-838.
25. Nam SY, Kim N, Kim JS, et al. Heat shock protein gene 70-2 polymorphism is differentially associated with the clinical phenotypes of ulcerative colitis and Crohn's disease. J Gastroenterol Hepatol. 2007; 22: 1032-1038.
26. De Zoeten EF, Wang L, Sai H, et al. Expression of HDAC9 by T regulatory cells prevents colitis in mice. Gastroenterology. 2010; 138: 538-594.
27. Polla BS, Bachelet M, Dall'Ava J, et al. Heat shock proteins in inflammation and asthma: Dr Jekill or Mr Hyde? Clin Exp Allergy. 1998; 29: 527-529.
28. Choi SR, Lee SA, Kim YJ, et al. Role of heat shock proteins in gastric inflammation and ulcer healing. J Physiol Pharmacol. 2009; 7: 5-17.
29. Bausero MA, Gastpar R, Multhoff G, et al. Alternative mechanism by which IFN-gamma enhances tumor recognition: active release of heat shock protein 72. J Immunol. 2005; 175: 2900-2912.
30. Tsan M, Gao B,. Heat shock proteins and the immune system. J Leuk Biol. 2009; 85: 905-910.
31. Marks DJB, Harbord MWN, MacAllister R, et al. Defective acute inflammation in Crohn's disease: a clinical investigation. Lancet. 2006; 367: 668-678.