Predicting torsade de pointes in acquired long QT syndrome: Optimal identification of critical QT interval prolongation

Cardiology (Switzerland)

Volumn 122, Issue 1, 2012, Pages 3-11

  Chiladakis, John ^a   Kalogeropoulos, Andreas ^a   Zagkli, Fani ^a   Koutsogiannis, Nikolaos ^a   Chouchoulis, Konstantinos ^a   Alexopoulos, Dimitrios ^a  

^a UNIVERSITY HOSPITAL OF PATRAS   (Greece)

Author keywords

Acquired long QT syndrome; QT interval prolongation; Torsade de pointes

Indexed keywords

AMIODARONE; AMPHOTERICIN B; IBUTILIDE; INDAPAMIDE; PROPAFENONE; QUINIDINE; QUINOLONE; SOTALOL; VENLAFAXINE;

ADULT; AGED; ARTICLE; ATRIOVENTRICULAR BLOCK; BRADYCARDIA; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG USE; FEMALE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART PACING; HEART RATE; HEART REPOLARIZATION; HEART RHYTHM; HEART RIGHT BUNDLE BRANCH BLOCK; HUMAN; HYPOKALEMIA; LONG QT SYNDROME; MALE; PRIORITY JOURNAL; QRS COMPLEX; QT PROLONGATION; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; SEX DIFFERENCE; SYNCOPE; TORSADE DES POINTES;

ADULT; AGED; CASE-CONTROL STUDIES; ELECTROCARDIOGRAPHY; FEMALE; HEART CONDUCTION SYSTEM; HUMANS; LONG QT SYNDROME; MALE; MIDDLE AGED; NOMOGRAMS; RETROSPECTIVE STUDIES; SEX FACTORS; TORSADES DE POINTES;

EID: 84861333164     PISSN: 00086312     EISSN: 14219751     Source Type: Journal    
DOI: 10.1159/000338345     Document Type: Article

References (26)

1. Jackman WM, Friday KJ, Anderson JL, Aliot EM, Clark M, Lazzara R: The long QT syndromes: a critical review, new clinical observations and a unifying hypothesis. Prog Cardiovasc Dis 1988; 31: 115-172.
2. Lin C, Ke X, Ranade V, Somberg J: Extracellular acidification and hyperkalemia induce changes in HERG inhibition by ibutilide. Cardiology 2008; 110: 209-216. (Pubitemid 351799059)
3. Hondeghem LM: Thorough QT/QTc not so thorough: removes torsadogenic predictors from the T-wave, incriminates safe drugs, and misses profibrillatory drugs. J Cardiovasc Electrophysiol 2006; 17: 337-340. (Pubitemid 43344952)
4. Heist EK, Ruskin JN: Drug-induced proarrhythmia and use of QTc-prolonging agents: clues for clinicians. Heart Rhythm 2005; 2:S1-S8. (Pubitemid 41600825)
5. Shah RR: Drugs, QTc interval prolongation and final ICH E14 guideline: an important milestone with challenges ahead. Drug Saf 2005; 28: 1009-1028. (Pubitemid 41483706)
6. Strasberg B, Kusniec J, Erdman S, Lewin RF, Arditti A, Sclarovsky S, Agmon J: Polymorphous ventricular tachycardia and atrioventricular block. Pacing Clin Electrophysiol 1986; 9: 522-526. (Pubitemid 16100198)
7. Díaz-Castro O, Puchol A, Almendral J, Torrecilla EG, Arenal A, Martínez-Selles M: Predictors of in-hospital ventricular fibrillation or torsades de pointes in patients with acute symptomatic bradycardia. J Electrocardiol 2004; 37: 55-60. (Pubitemid 38168830)
8. Habbab MA, El-Sherif N: TU alternans, long QTU, and torsade de pointes: clinical and experimental observations. Pacing Clin Electrophysiol 1992; 15: 916-931.
9. Rautaharju PM, Surawicz B, Gettes LS, Bailey JJ, Childers R, Deal BJ, Gorgels A, Hancock EW, Josephson M, Kligfield P, Kors JA, Macfarlane P, Mason JW, Mirvis DM, Okin P, Pahlm O, van Herpen G, Wagner GS, Wellens H; American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; American College of Cardiology Foundation; Heart Rhythm Society: AHA/ACCF/HRS recommendations for the standardization and interpretation of the electrocardiogram: part IV: the ST segment, T and U waves, and the QT interval: a scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society: endorsed by the International Society for Computerized Electrocardiology. Circulation 2009; 119:e241-e250.
10. E14 Clinical Evaluation of QT/QTc Interval Prolongation and Proarrhythmic Potential of Non-Antiarrhythmic Drugs. Rockville, US Department of Health and Human Services, Food and Drug Administration, 2005.
11. Rautaharju PM, Warren JW, Calhoun HP: Estimation of QT prolongation. A persistent, avoidable error in computer electrocardiography. J Electrocardiol 1990; 23: 111-117.
12. Malik M: Problems of heart rate correction in assessment of drug-induced QT interval prolongation. J Cardiovasc Electrophysiol 2001; 12: 411-420. (Pubitemid 32324653)
13. Bai R, Yan GX: Accurate interpretation of the QT interval: a vital task that remains unaccomplished. Heart Rhythm 2005; 2: 575-577. (Pubitemid 40724121)
14. Aytemir K, Maarouf N, Gallagher MM, Yap YG, Waktare JEP, Malik M: Comparison of formulae for heart rate correction of QT interval in exercise electrocardiograms. Pacing Clin Electrophysiol 1999; 22: 1397-1401. (Pubitemid 29485042)
15. Chiladakis J, Kalogeropoulos A, Arvanitis P, Koutsogiannis N, Zagli F, Alexopoulos D: Preferred QT correction formula for the assessment of drug-induced QT interval prolongation. J Cardiovasc Electrophysiol 2010; 21: 905-913.
16. Bazett JC: An analysis of time relations of electrocardiograms. Heart 1920; 7: 353-767.
17. Sagie A, Larson MG, Goldberg RJ, Bengtson JR, Levy D: An improved method for adjusting the QT interval for heart rate (the Framingham Heart Study). Am J Cardiol 1992; 70: 797-801.
18. Luo S, Michler K, Johnston P, Macfarlane PW: A comparison of commonly used QT correction formulae: the effect of heart rate on the QTc of normal ECGs. J Electrocardiol 2004; 37: 81-90. (Pubitemid 39452873)
19. Karjalainen J, Viitasalo M, Manttari M, Manninen V: Relation between QT intervals and heart rates from 40 to 120 beats per minute in rest electrocardiograms of men and a simple method to adjust QT interval values. J Am Coll Cardiol 1994; 23: 1547-1553. (Pubitemid 24182117)
20. Fridericia LS: Die Systolendauer im Elektrokardiogramm bei normalen Menschen und bei Herzkranken. Acta Med Scand 1920; 53: 469-486.
21. Rautaharju PM, Zhang ZM, Prineas R, Heiss G: Assessment of prolonged QT and JT intervals in ventricular conduction defects. Am J Cardiol 2004; 93: 1017-1021. (Pubitemid 38479457)
22. Moss AJ, Zareba W, Benhorin J, Locati EH, Hall WJ, Robinson JL, Schwartz PJ, Towbin JA, Vincent GM, Lehmann MH: ECG Twave patterns in genetically distinct forms of the hereditary long QT syndrome. Circulation 1995; 92: 2929-2934.
23. Couderc JP, Xia J, Xu X, Kaab S, Hinteeser M, Zareba W: Static and dynamic electrocardiographic patterns preceding torsades de pointes in the acquired and congenital long QT syndrome. Comput Cardiol 2010; 37: 357-360.
24. Haraoka K, Morita H, Saito Y, Toh N, Miyoshi T, Nishii N, Nagase S, Nakamura K, Kohno K, Kusano K, Kawaguchi K, Ohe T, Ito H: Fragmented QRS is associated with torsades de pointes in patients with acquired long QT syndrome. Heart Rhythm 2010; 7: 1808-1814.
25. Surawicz B, Childers R, Deal BJ, Gettes LS, Bailey JJ, Gorgels A, Hancock EW, Josephson M, Kligfield P, Kors JA, Macfarlane P, Mason JW, Mirvis DM, Okin P, Pahlm O, Rautaharju PM, van Herpen G, Wagner GS, Wellens H; American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; American College of Cardiology Foundation; Heart Rhythm Society: AHA/ACCF/HRS recommendations for the standardization and interpretation of the electrocardiogram: part III: intraventricular conduction disturbances: a scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society. Endorsed by the International Society for Computerized Electrocardiology. J Am Coll Cardiol 2009; 53: 976-981.
26. Crow RS, Hannan PJ, Folsom AR: Prognostic significance of corrected QT and corrected JT interval for incident coronary heart disease in a general population sample stratified by presence or absence of wide QRS complex: the ARIC Study with 13 years of follow-up. Circulation 2003; 108: 1985-1989. (Pubitemid 37296543)