Endophthalmitis following intravitreal injection versus endophthalmitis following cataract surgery: Clinical features, causative organisms and post-treatment outcomes

British Journal of Ophthalmology

Volumn 96, Issue 6, 2012, Pages 862-866

  Simunovic, Matthew P ^a,b   Rush, Ryan B ^a   Hunyor, Alex P ^a,b   Chang, Andrew A ^a,b  

^a SYDNEY EYE HOSPITAL   (Australia)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BEVACIZUMAB; RANIBIZUMAB; TRIAMCINOLONE;

ACUTE ENDOPHTHALMITIS; AGED; ARTICLE; CASE STUDY; CATARACT EXTRACTION; CLINICAL FEATURE; CONTROLLED STUDY; ENDOPHTHALMITIS; ENUCLEATION; HUMAN; MAJOR CLINICAL STUDY; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RETROSPECTIVE STUDY; STREPTOCOCCUS; TERTIARY HEALTH CARE; TREATMENT OUTCOME; VISUAL ACUITY;

AGED; ANGIOGENESIS INHIBITORS; ANTI-BACTERIAL AGENTS; BACTERIA; CATARACT EXTRACTION; ENDOPHTHALMITIS; EYE ENUCLEATION; EYE INFECTIONS, BACTERIAL; FEMALE; GLUCOCORTICOIDS; HUMANS; INCIDENCE; INTRAVITREAL INJECTIONS; MALE; RETROSPECTIVE STUDIES; TIME FACTORS; VISUAL ACUITY; VITRECTOMY; VITREOUS BODY;

EID: 84861332315     PISSN: 00071161     EISSN: 14682079     Source Type: Journal    
DOI: 10.1136/bjophthalmol-2011-301439     Document Type: Article

References (29)

1. Miller JJ, Scott IU, Flynn HW Jr, et al. Acute-onset endophthalmitis after cataract surgery (2000-2004): incidence, clinical settings, and visual acuity outcomes after treatment. Am J Ophthalmol 2005;139:983-7.
2. Barry P, Seal DV, Gettinby G, et al. ESCRS study of prophylaxis of postoperative endophthalmitis after cataract surgery: preliminary report of principal results from a European multicenter study. J Cataract Refract Surg 2006;32:407-10. (Pubitemid 44313820)
3. Aaberg TM Jr, Flynn HW Jr, Schiffman J, et al. Nosocomial acute-onset postoperative endophthalmitis survey. A 10-year review of incidence and outcomes. Ophthalmology 1998;105:1004-10. (Pubitemid 28268323)
4. Eifrig CW, Flynn HW Jr, Scott IU, et al. Acute-onset postoperative endophthalmitis: review of incidence and visual outcomes (1995-2001). Ophthalmic Surg Lasers 2002;33:373-8. (Pubitemid 44714242)
5. Wykoff CC, Parrott MB, Flynn HW Jr, et al. Nosocomial acute-onset postoperative endophthalmitis at a university teaching hospital (2002-2009). Am J Ophthalmol 2010;150:392-8.e2.
6. Mason JO 3rd, White MF, Feist RM, et al. Incidence of acute onset endophthalmitis following intravitreal bevacizumab (Avastin) injection. Retina 2008;28:564-7. (Pubitemid 351589565)
7. Scott IU, Edwards AR, Beck RW, et al. A phase II randomized clinical trial of intravitreal bevacizumab for diabetic macular edema. Ophthalmology 2007;114:1860-7.
8. McCannel CA. Meta-analysis of endophthalmitis after intravitreal injection of anti-vascular endothelial growth factor agents: causative organisms and possible prevention strategies. Retina 2011;31:654-61.
9. Miller JJ, Scott IU, Flynn HW Jr, et al. Endophthalmitis caused by Streptococcus pneumoniae. Am J Ophthalmol 2004;138:231-6. (Pubitemid 39037427)
10. Moshfeghi AA, Rosenfeld PJ, Flynn HW Jr, et al. Endophthalmitis after intravitreal anti-vascular endothelial growth factor antagonists: a six-year experience at a University Referral Center. Retina 2011;31:662-8.
11. Gordon DF, Jong BB. Indigenous flora from human saliva. Appl Microbiol 1968;16:428-9.
12. Chen E, Lin MY, Cox J, et al. Endophthalmitis after intravitreal injection: the importance of viridans streptococci. Retina 2011;31:1525-33.
13. Irigoyen C, Ziahosseini K, Morphis G, et al. Endophthalmitis following intravitreal injections. Graefes Arch Clin Exp Ophthalmol. Published Online First: 3 November 2011. doi:10.1007/s00417-011-1851-1
14. Ferris FL 3rd, Kassoff A, Bresnick GH, et al. New visual acuity charts for clinical research. Am J Ophthalmol 1982;94:91-6. (Pubitemid 12080556)
15. Holladay JT. Proper method for calculating average visual acuity. J Refract Surg 1997;13:388-91. (Pubitemid 27369067)
16. Lowry R. VassarStats. http://faculty.vassar.edu/lowry/VassarStats.html (accessed Nov 2011).
17. Radua J, Mataix-Cols D. SDM Project. http://sdmproject.com/utilities/? show=FDR (accessed Nov 2011).
18. Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc B 1995;57:289-300.
19. Moss JM, Sanislo SR, Ta CN. A prospective randomized evaluation of topical gatifloxacin on conjunctival flora in patients undergoing intravitreal injections. Ophthalmology 2009;116:1498-501.
20. Aas JA, Paster BJ, Stokes LN, et al. Defining the normal bacterial flora of the oral cavity. J Clin Microbiol 2005;43:5721-32. (Pubitemid 41612354)
21. Veringa E, van Belkum A, Schellekens H. Iatrogenic meningitis by Streptococcus salivarius following lumbar puncture. J Hosp Infect 1995;29:316-18.
22. O'Kelly SW, Marsh D. Face masks and spinal anaesthesia. Br J Anaesth 1993;70:239.
23. McLure HA, Talboys CA, Yentis SM, et al. Surgical face masks and downward dispersal of bacteria. Anaesthesia 1998;53:624-6. (Pubitemid 28342392)
24. Trautmann M, Lepper PM, Schmitz FJ. Three cases of bacterial meningitis after spinal and epidural anesthesia. Eur J Clin Microbiol Infect Dis 2002;21:43-5. (Pubitemid 34158505)
25. Reeves KD, Horvat RT. Aerosolized alpha-hemolytic Streptococcus as a cause of knee sepsis after intra-articular injection: predisposing factors. Am J Phys Med Rehabil 2010;89:77-82.
26. Philips BJ, Fergusson S, Armstrong P, et al. Surgical face masks are effective in reducing bacterial contamination caused by dispersal from the upper airway. Br J Anaesth 1992;69:407-8.
27. Alwitry A, Jackson E, Chen H, et al. The use of surgical facemasks during cataract surgery: is it necessary? Br J Ophthalmol 2002;86:975-7. (Pubitemid 34953607)
28. Leyland M, Bacon A, Watson SL. Risk factors for endophthalmitis: does non-wearing of face-masks increase relative risk? Eye (Lond) 2007;21:1441; author reply 1441-2.
29. Maylath FR, Leopold IH. Study of experimental intraocular infection. Am J Ophthalmol 1955;40:86-101.