메뉴 건너뛰기




Volumn 5, Issue , 2011, Pages 369-374

Management of oropharyngeal candidiasis with localized oral miconazole therapy: Efficacy, safety, and patient acceptability

Author keywords

Antifungal agents; Esophageal candidiasis; Miconazole

Indexed keywords

CLOTRIMAZOLE; FLUCONAZOLE; KETOCONAZOLE; LAURIAD; LORAMYC; MICONAZOLE; PLACEBO; UNCLASSIFIED DRUG; WARFARIN;

EID: 84861305377     PISSN: None     EISSN: 1177889X     Source Type: Journal    
DOI: 10.2147/PPA.S14047     Document Type: Review
Times cited : (26)

References (28)
  • 1
    • 84964959524 scopus 로고    scopus 로고
    • Candidiasis (oropharyngeal)
    • Epub 2009 Mar 18
    • Pankhurst CL. Candidiasis (oropharyngeal). Clin Evid (Online). 2009;2009:1304. Epub 2009 Mar 18.
    • (2009) Clin Evid (Online). , vol.2009 , pp. 1304
    • Pankhurst, C.L.1
  • 2
    • 0032135510 scopus 로고    scopus 로고
    • Candida-associated denture stomatitis. Aetiology and management: A review. Part 3. Treatment of oral candidosis
    • Webb BC, Thomas CJ, Willcox MD, Harty DW, Knox KW. Candida-associated denture stomatitis. Aetiology and management: a review. Part 3. Treatment of oral candidosis. Aust Dent J. 1998;43(4):244-249.
    • (1998) Aust Dent J. , vol.43 , Issue.4 , pp. 244-249
    • Webb, B.C.1    Thomas, C.J.2    Willcox, M.D.3    Harty, D.W.4    Knox, K.W.5
  • 5
    • 77956458554 scopus 로고    scopus 로고
    • A systematic review of oral fungal infections in patients receiving cancer therapy
    • Lalla RV, Latortue MC, Hong CH, et al. A systematic review of oral fungal infections in patients receiving cancer therapy. Support Care Cancer. 2010;18(8):985-992.
    • (2010) Support Care Cancer. , vol.18 , Issue.8 , pp. 985-992
    • Lalla, R.V.1    Latortue, M.C.2    Hong, C.H.3
  • 6
    • 84866509102 scopus 로고    scopus 로고
    • Summary Review: Application 22404Orig1s000; NDA22-404
    • Center for Drug Evaluation and Research, US Food and Drug Administration (FDA), US Center for Drug Evaluation and Research; 2010. Available at:, Accessed May 12,
    • Center for Drug Evaluation and Research, US Food and Drug Administration (FDA). Summary Review: application 22404Orig1s000; NDA22-404, Oravig (miconazole) for oropharyngeal candidiasis. US Center for Drug Evaluation and Research; 2010. Available at: http://www. accessdata.fda.gov/drugsatfda_docs/nda/2010/022404Orig1s000SumR. pdf. Accessed May 12, 2011.
    • (2011) Oravig (miconazole) for oropharyngeal candidiasis
  • 7
    • 84866509097 scopus 로고    scopus 로고
    • Woodcliff Lake, NJ: Strativa Pharmaceuticals, a division of Par Pharmaceutical, Inc; 2010. Oravig [prescribing information], Available at, Accessed May 12,
    • Oravig [prescribing information]. Woodcliff Lake, NJ: Strativa Pharmaceuticals, a division of Par Pharmaceutical, Inc; 2010. Available at: www.oravig.com/oral-thrush-once-daily/hcp-faqs.html. Accessed May 12, 2011.
    • (2011)
  • 8
    • 33645767664 scopus 로고    scopus 로고
    • In vitro antifungal susceptibility to six antifungal agents of 229 Candida isolates from patients with diabetes mellitus
    • Manfredi M, McCullough MJ, Polonelli L, et al. In vitro antifungal susceptibility to six antifungal agents of 229 Candida isolates from patients with diabetes mellitus. Oral Microbiol Immunol. 2006;21(3):177-182.
    • (2006) Oral Microbiol Immunol. , vol.21 , Issue.3 , pp. 177-182
    • Manfredi, M.1    McCullough, M.J.2    Polonelli, L.3
  • 9
    • 0042320831 scopus 로고    scopus 로고
    • Susceptibility to 5-fluorocytosine, miconazole and amphotericin B of Candida albicans strains isolated from the throat of non-AIDS patients
    • Luz Paniagua GC, Monroy EP, Negrete EA, Vaca SP. Susceptibility to 5-fluorocytosine, miconazole and amphotericin B of Candida albicans strains isolated from the throat of non-AIDS patients. Rev Latinoam Microbiol. 2002;44(2):65-68.
    • (2002) Rev Latinoam Microbiol. , vol.44 , Issue.2 , pp. 65-68
    • Luz Paniagua, G.C.1    Monroy, E.P.2    Negrete, E.A.3    Vaca, S.P.4
  • 10
    • 0032580438 scopus 로고    scopus 로고
    • Induced expression of Candida albicans multidrug resistance gene CDR1 in response to fluconazole and other antifungals
    • Hernáez ML, Gil C, Pla J, Nombela C. Induced expression of Candida albicans multidrug resistance gene CDR1 in response to fluconazole and other antifungals. Yeast. 1998;14(6):517-526.
    • (1998) Yeast. , vol.14 , Issue.6 , pp. 517-526
    • Hernáez, M.L.1    Gil, C.2    Pla, J.3    Nombela, C.4
  • 11
    • 77955781558 scopus 로고    scopus 로고
    • Antifungal activity of miconazole against recent Candida strains
    • Isham N, Ghannoum MA. Antifungal activity of miconazole against recent Candida strains. Mycoses. 2010;53(5):434-437.
    • (2010) Mycoses. , vol.53 , Issue.5 , pp. 434-437
    • Isham, N.1    Ghannoum, M.A.2
  • 12
    • 84866489327 scopus 로고    scopus 로고
    • Repeated exposure of Candida spp. to miconazole demonstrates no development of resistance
    • Mar 4. [Epub ahead of print]
    • Ghannoum MA, Herbert J, Isham N. Repeated exposure of Candida spp. to miconazole demonstrates no development of resistance. Mycoses. 2010 Mar 4. [Epub ahead of print]
    • (2010) Mycoses
    • Ghannoum, M.A.1    Herbert, J.2    Isham, N.3
  • 13
    • 4744370804 scopus 로고    scopus 로고
    • Comparison of the pharmacokinetics of miconazole after administration via a bioadhesive slow release tablet and an oral gel to healthy male and female subjects
    • Cardot JM, Chaumont C, Dubray C, Constantini D, Aiache JM. Comparison of the pharmacokinetics of miconazole after administration via a bioadhesive slow release tablet and an oral gel to healthy male and female subjects. Br J Clin Pharmacol. 2004;58(4): 345-351.
    • (2004) Br J Clin Pharmacol. , vol.58 , Issue.4 , pp. 345-351
    • Cardot, J.M.1    Chaumont, C.2    Dubray, C.3    Constantini, D.4    Aiache, J.M.5
  • 14
    • 0037356695 scopus 로고    scopus 로고
    • Safety, acceptability, and adhesion of novel bioadhesive slow release tablet of miconazole in a phase I study
    • Chaumont C, Cardot JM, Dubray C, Constantini D, Aiache JM. Safety, acceptability, and adhesion of novel bioadhesive slow release tablet of miconazole in a phase I study. Journal de mycologie médicale. 2003; 13:13-18.
    • (2003) Journal de mycologie médicale. , vol.13 , pp. 13-18
    • Chaumont, C.1    Cardot, J.M.2    Dubray, C.3    Constantini, D.4    Aiache, J.M.5
  • 15
    • 1642499252 scopus 로고    scopus 로고
    • Comparative efficacy of topical therapy with a slow-release mucoadhesive buccal tablet containing miconazole nitrate versus systemic therapy with ketoconazole in HIV-positive patients with oropharyngeal candidiasis
    • Van Roey J, Haxaire M, Kamya M, Lwanga I, Katabira I. Comparative efficacy of topical therapy with a slow-release mucoadhesive buccal tablet containing miconazole nitrate versus systemic therapy with ketoconazole in HIV-positive patients with oropharyngeal candidiasis. J Acquir Immune Defic Syndr. 2004;35(2): 144-150.
    • (2004) J Acquir Immune Defic Syndr. , vol.35 , Issue.2 , pp. 144-150
    • Van Roey, J.1    Haxaire, M.2    Kamya, M.3    Lwanga, I.4    Katabira, I.5
  • 16
    • 37449017575 scopus 로고    scopus 로고
    • Comparison of the efficacy and safety of miconazole 50 mg mucoadhesive buccal tablets with miconazole 500 mg gel in the treatment of oropharyngeal candidiasis: A prospective, randomized, single-blind, multicenter, comparative, phase III trial in patients treated with radiotherapy for head and neck cancer
    • Bensadoun RJ, Daoud J, El Gueddari B, et al. Comparison of the efficacy and safety of miconazole 50 mg mucoadhesive buccal tablets with miconazole 500 mg gel in the treatment of oropharyngeal candidiasis: a prospective, randomized, single-blind, multicenter, comparative, phase III trial in patients treated with radiotherapy for head and neck cancer. Cancer. 2008;112(1):204-211.
    • (2008) Cancer. , vol.112 , Issue.1 , pp. 204-211
    • Bensadoun, R.J.1    Daoud, J.2    El Gueddari, B.3
  • 17
    • 78049426668 scopus 로고    scopus 로고
    • Randomized, comparative, doubleblind, double-dummy, multicenter trial of miconazole buccal tablet and clotrimazole troches for the treatment of oropharyngeal candidiasis: Study of miconazole Lauriad® efficacy and safety (SMiLES)
    • Vazquez JA, Patton LL, Joel B, et al. Randomized, comparative, doubleblind, double-dummy, multicenter trial of miconazole buccal tablet and clotrimazole troches for the treatment of oropharyngeal candidiasis: study of miconazole Lauriad® efficacy and safety (SMiLES). HIV clinical trials. 2010;11(4):186-196.
    • (2010) HIV clinical trials. , vol.11 , Issue.4 , pp. 186-196
    • Vazquez, J.A.1    Patton, L.L.2    Joel, B.3
  • 18
    • 54249128253 scopus 로고    scopus 로고
    • Single-dose fluconazole versus standard 2-week therapy for oropharyngeal candidiasis in HIVinfected patients: A randomized, double-blind, double-dummy trial
    • Hamza OJ, Matee MI, Bruggemann RJ, et al. Single-dose fluconazole versus standard 2-week therapy for oropharyngeal candidiasis in HIVinfected patients: a randomized, double-blind, double-dummy trial. Clin Infect Dis. 2008;47(10):1270-1276.
    • (2008) Clin Infect Dis. , vol.47 , Issue.10 , pp. 1270-1276
    • Hamza, O.J.1    Matee, M.I.2    Bruggemann, R.J.3
  • 19
    • 33645782259 scopus 로고    scopus 로고
    • A multicenter randomized trial evaluating posaconazole versus fluconazole for the treatment of oropharyngeal candidiasis in subjects with HIV/AIDS
    • Vazquez JA, Skiest DJ, Nieto L, et al. A multicenter randomized trial evaluating posaconazole versus fluconazole for the treatment of oropharyngeal candidiasis in subjects with HIV/AIDS. Clin Infect Dis. 2006;42(8):1179-1186.
    • (2006) Clin Infect Dis. , vol.42 , Issue.8 , pp. 1179-1186
    • Vazquez, J.A.1    Skiest, D.J.2    Nieto, L.3
  • 20
    • 33846902613 scopus 로고    scopus 로고
    • Posaconazole for the treatment of azole-refractory oropharyngeal and esophageal candidiasis in subjects with HIV infection
    • Skiest DJ, Vazquez JA, Anstead GM, et al. Posaconazole for the treatment of azole-refractory oropharyngeal and esophageal candidiasis in subjects with HIV infection. Clin Infect Dis. 2007;44(4): 607-614.
    • (2007) Clin Infect Dis. , vol.44 , Issue.4 , pp. 607-614
    • Skiest, D.J.1    Vazquez, J.A.2    Anstead, G.M.3
  • 21
    • 60549098868 scopus 로고    scopus 로고
    • Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America
    • Pappas PG, Kauffman CA, Andes D, et al. Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America. Clin Infect Dis. 2009;48(5): 503-535.
    • (2009) Clin Infect Dis. , vol.48 , Issue.5 , pp. 503-535
    • Pappas, P.G.1    Kauffman, C.A.2    Andes, D.3
  • 22
    • 0035503456 scopus 로고    scopus 로고
    • A randomized double-blind study of caspofungin versus amphotericin for the treatment of candidal esophagitis
    • Villanueva, Arathoon EG, Gotuzzo E, Berman RS, DiNubile MJ, Sable CA. A randomized double-blind study of caspofungin versus amphotericin for the treatment of candidal esophagitis. Clin Infect Dis. 2001; 33(9):1529-1535.
    • (2001) Clin Infect Dis. , vol.33 , Issue.9 , pp. 1529-1535
    • Villanueva1    Arathoon, E.G.2    Gotuzzo, E.3    Berman, R.S.4    DiNubile, M.J.5    Sable, C.A.6
  • 23
    • 70449464972 scopus 로고    scopus 로고
    • Is there a role for therapeutic drug monitoring of antifungal agents?
    • Smith JA. Is there a role for therapeutic drug monitoring of antifungal agents? Curr Infect Dis Rep. 2009;11(6):439-446.
    • (2009) Curr Infect Dis Rep. , vol.11 , Issue.6 , pp. 439-446
    • Smith, J.A.1
  • 24
    • 33645790503 scopus 로고    scopus 로고
    • Oropharyngeal candidiasis: A new treatment option
    • Klotz SA. Oropharyngeal candidiasis: a new treatment option. Clin Infect Dis. 2006;42(8):1187-1188.
    • (2006) Clin Infect Dis. , vol.42 , Issue.8 , pp. 1187-1188
    • Klotz, S.A.1
  • 25
    • 33947408476 scopus 로고    scopus 로고
    • Who Technical Report Series, No 920
    • Available at, Js4881e.4.1.5. Accessed April 11,
    • Who Technical Report Series, No. 920. The selection and use of essential medicines. Available at: http://apps.who.int/medicinedocs/en/d/Js 4881e/4.1.5.html#Js4881e.4.1.5. Accessed April 11, 2011.
    • (2011) The selection and use of essential medicines
  • 26
    • 77952693197 scopus 로고    scopus 로고
    • Oral candidiasis and angular cheilitis
    • Sharon V, Fazel N. Oral candidiasis and angular cheilitis. Dermatol Ther. 2010;23(3):230-242.
    • (2010) Dermatol Ther. , vol.23 , Issue.3 , pp. 230-242
    • Sharon, V.1    Fazel, N.2
  • 27
    • 79952112498 scopus 로고    scopus 로고
    • Miconazole (Oravig) for oropharyngeal candidiasis
    • Miconazole (Oravig) for oropharyngeal candidiasis. Med Lett Drugs Ther. 2010;29;52(1352):95-96.
    • (2010) Med Lett Drugs Ther , vol.29-52 , Issue.1352 , pp. 95-96
  • 28
    • 84866509104 scopus 로고    scopus 로고
    • Montvale, NJ: Thomson Healthcare
    • 2010 Redbook. Montvale, NJ: Thomson Healthcare; 2010.
    • (2010) 2010 Redbook


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.