Natural coniferous resin salve used to treat complicated surgical wounds: Pilot clinical trial on healing and costs

International Journal of Dermatology

Volumn 51, Issue 6, 2012, Pages 726-732

  Sipponen, Arno ^a   Kuokkanen, Opri ^b   Tiihonen, Raine ^a   Kauppinen, Harri ^c   Jokinen, Janne J ^d  

^a PÄIJÄT HÄME CENTRAL HOSPITAL   (Finland)

^b JORVI HOSPITAL   (Finland)

^c KYMENLAAKSO CENTRAL HOSPITAL   (Finland)

^d HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

ABILAR; ANTIINFECTIVE AGENT; CORTICOSTEROID; IMMUNOSUPPRESSIVE AGENT; METHOTREXATE; RESIN SALVE; UNCLASSIFIED DRUG;

ACINETOBACTER; ADOLESCENT; ADULT; ALLERGIC REACTION; ARTICLE; BACTERIUM CULTURE; CLINICAL ARTICLE; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; DRUG COST; EPITHELIZATION; FEMALE; HEALTH CARE COST; HUMAN; IMMOBILIZATION; MALE; NORWAY SPRUCE; PASTEURELLA MULTOCIDA; PATIENT COMPLIANCE; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; STREPTOCOCCUS; STREPTOCOCCUS AGALACTIAE; SURGICAL INFECTION; TREATMENT DURATION; WOUND CARE; WOUND HEALING; WOUND HEALING IMPAIRMENT;

ADOLESCENT; ADRENAL CORTEX HORMONES; ADULT; AGED; AGED, 80 AND OVER; FEMALE; HUMANS; IMMOBILIZATION; IMMUNOSUPPRESSIVE AGENTS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; OINTMENTS; PHYTOTHERAPY; PICEA; PILOT PROJECTS; POSTOPERATIVE COMPLICATIONS; RESINS, PLANT; WOUND HEALING; YOUNG ADULT;

EID: 84861305192     PISSN: 00119059     EISSN: 13654632     Source Type: Journal    
DOI: 10.1111/j.1365-4632.2011.05397.x     Document Type: Article

References (23)

1. Perret L. [Benedictus Olai: a useful book of medicine, 1578. A quadricentennial. Some aspects of sixteenth-century healing arts.] Nord Medicinhist Arsb 1980; 6: 118-121.
2. Sipponen A, Lohi J. [Lappish resin salve treatment -"new" therapy for pressure sores? Ideal folk medicine.] Finnish Med J 2003; 38: 3775-3776.
3. Sipponen A, Jokinen JJ, Lohi J. Resin salve from the Norwegian spruce tree: a "novel" method for the treatment of chronic wounds. J Wound Care 2007; 16: 72-74.
4. Sipponen A, Rautio M, Jokinen JJ, et al. Resin salve from Norway spruce - a potential method to treat infected chronic skin ulcers? Drug Metab Lett 2007; 1: 143-145.
5. Raikin SM, Kane J, Ciminiello ME. Risk factors for incision-healing complications following total ankle arthroplasty. J Bone Joint Surg Am 2010; 92: 2150-2155.
6. Park H, Copeland C, Henry S, Barbul A. Complex wounds and their management. Surg Clin North Am 2010; 90: 1181-1194.
7. Fabiano G, Pezzolla A, Filograna MA, Ferrarese F. Risk factors of surgical wound infection. Ann Ital Chir 2004; 75: 11-16.
8. Anderson DJ. Surgical site infections. Infect Dis Clin North Am 2011; 25: 135-153.
9. Kirby JP, Mazuski JE. Prevention of surgical site infection. Surg Clin North Am 2009; 89: 365-389.
10. Rautio M, Sipponen A, Peltola R, et al. Antibacterial effects of home-made resin salve from Norway spruce (Picea abies). APMIS 2007; 115: 335-340.
11. Sipponen A, Jokinen JJ, Sipponen P, et al. Beneficial effect of resin salve in treatment of severe pressure ulcer - a prospective, randomized and controlled multicenter trial. Br J Dermatol 2008; 124: 1364-1369.
12. Sipponen A, Peltola R, Jokinen JJ, et al. Effects of Norway spruce (Picea abies) resin on cell wall and cell membrane of Staphylococcus aureus. Ultrastruct Pathol 2009; 33: 128-135.
13. von Elm E, Altman DG, Egger M, et al. STROBE Initiative. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. J Clin Epidemiol 2008; 61: 344-349.
14. Adlercreutz H. Lignans and human health. Crit Rev Clin Lab Sci 2007; 44: 483-525.
15. Shealy FG, DeLoach ED. Experience with the use of apligraft to heal complicated surgical and non-surgical wounds in a private practice setting. Adv Skin Wound Care 2006; 19: 310-322.
16. Ubbink DT, Vermeulen H, Goossens A, et al. Occlusive vs. gauze dressings for local wound care in surgical patients: a randomized clinical trial. Arch Surg 2008; 143: 950-955.
17. Abbott RD, Carroll RJ. Interpreting multiple logistic regression coefficients in prospective observational studies. Am J Epidemiol 1984; 5: 830-836.
18. Vermeulen H, Ubbink D, Goossens A, et al. Dressings and topical agents for surgical wounds healing by secondary intention. Cochrane Database Syst Rev 2004; 2: CD003554.
19. Lewis R, Whiting P, ter Riet G, et al. A rapid and systematic review of the clinical effectiveness and cost-effectiveness of debriding agents in treating surgical wounds healing by secondary intention. Health Technol Assess 2001; 5: 1-131.
20. Bruce J, Russell EM, Mollison J, Krukowski ZH. The measurement and monitoring of surgical adverse events. Health Technol Assess 2001; 5: 1-194.
21. Färm G. Contact allergy to colophony. Clinical and experimental studies with emphasis on clinical relevance. Acta Derm Venereol Suppl (Stockh) 1998; 201: 1-42.
22. Estlander T, Jolanki R, Alanko K, Kanerva L. Occupational allergic contact dermatitis caused by wood dusts. Contact Dermatitis 2001; 44: 213-217.
23. Hausen BM, Börries M, Budianto E, Krohn K. Contact allergy due to colophony. Sensitization studies with further products isolated after oxidative degradation of resin acids and colophony. Contact Dermatitis 1993; 29: 234-240.