Inhibitory Killer Immunoglobulin-like receptors to self HLA-B and HLA-C ligands contribute differentially to Natural Killer cell functional potential in HIV infected slow progressors

Clinical Immunology

Volumn 143, Issue 3, 2012, Pages 246-255

  Kamya, Philomena ^a,b   Tallon, Benjamin ^a,b   Melendez Pena, Carlos ^a,b   Parsons, Matthew S ^a,b   Migueles, Stephen A ^c   Connors, Mark ^c   Miconiatis, Sofia ^a,b   Song, Rujun ^a,b   Boulet, Salix ^d   Bruneau, Julie ^e   Tremblay, Cecile L ^e   Bernard, Nicole F ^a  

^a RESEARCH INSTITUTE OF THE MCGILL UNIVERSITY HEALTH CENTRE   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^d UNIVERSITY OF MONTREAL   (Canada)

^e CENTRE HOSPITALIER DE L UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

HLA ligands; Killer Immunoglobulin like Receptors; Natural Killer (NK) cells; NK function

Indexed keywords

GAMMA INTERFERON; HLA B ANTIGEN; HLA C ANTIGEN; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ALLELE; ARTICLE; CELL ACTIVATION; CELL FUNCTION; CELL INTERACTION; CELL STIMULATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE COURSE; FEMALE; GENE LOCUS; GENETIC CODE; HOMOZYGOTE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; MALE; NATURAL KILLER CELL; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADULT; AGED; CD4 LYMPHOCYTE COUNT; FEMALE; HIV INFECTIONS; HLA-B ANTIGENS; HLA-C ANTIGENS; HUMANS; K562 CELLS; KILLER CELLS, NATURAL; MIDDLE AGED; RECEPTORS, KIR; YOUNG ADULT;

EID: 84861226729     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2012.01.001     Document Type: Article

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