Determination of dalcetrapib by liquid chromatography-tandem mass spectrometry

Journal of Pharmaceutical and Biomedical Analysis

Volumn 66, Issue , 2012, Pages 314-324

  Heinig, Katja ^a   Bucheli, Franz ^a   Kuhlmann, Olaf ^a   Zell, Manfred ^a   Pähler, Axel ^a   Zwanziger, Elke ^a   Gross, Günter ^a   Tardio, Joseph ^a   Ishikawa, Tomohiro ^b   Yamashita, Tomoko ^b  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b JAPAN TOBACCO INC   (Japan)

Author keywords

Column switching; Dalcetrapib; Dithiothreitol; Liquid chromatography tandem mass spectrometry; N ethylmaleimide; Thioester

Indexed keywords

DALCETRAPIB; DITHIOTHREITOL; GLUCURONIDE; N ETHYLMALEIMIDE; PANCREATIN; POLYSORBATE 80; THIOL DERIVATIVE;

ARTICLE; BLOOD SAMPLING; DERIVATIZATION; DISULFIDE BOND; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG HYDROLYSIS; HUMAN; LIQUID CHROMATOGRAPHY; NONHUMAN; PRIORITY JOURNAL; STOMACH JUICE; STOMACH PH; TANDEM MASS SPECTROMETRY; URINALYSIS;

ANIMALS; ANTICHOLESTEREMIC AGENTS; CHROMATOGRAPHY, LIQUID; CRICETINAE; GLUCURONIDES; HUMANS; LIMIT OF DETECTION; MACACA FASCICULARIS; METHYLATION; MICE; POLYSORBATES; RABBITS; RATS; REPRODUCIBILITY OF RESULTS; SPECIES SPECIFICITY; SULFHYDRYL COMPOUNDS; SURFACE-ACTIVE AGENTS; TANDEM MASS SPECTROMETRY;

EID: 84861225705     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2012.03.056     Document Type: Article

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