Quantitative determination of BAF312, a S1P-R modulator, in human urine by LC-MS/MS: Prevention and recovery of lost analyte due to container surface adsorption

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 878, Issue 5-6, 2010, Pages 583-589

  Li, Wenkui ^a   Luo, Suyi ^a   Smith, Harold T ^a   Tse, Francis L S ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

cyclodextrin; BAF312; Bovine Serum Albumin (BSA); CHAPS; Container Surface Absorption; LC MS MS; Tween 80; Urine assay

Indexed keywords

BAF312; BOVINE SERUM ALBUMINS; LC-MS/MS; SURFACE ABSORPTION; TWEEN 80;

ABSORPTION; ADSORPTION; CONTAINERS; IONIZATION OF LIQUIDS; LIQUIDS; LOSS PREVENTION; QUANTUM THEORY; SOLVENT EXTRACTION; SURFACE ACTIVE AGENTS;

BODY FLUIDS;

BAF 312; BETA CYCLODEXTRIN; IMMUNOSUPPRESSIVE AGENT; POLYSORBATE 80; SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATOR; UNCLASSIFIED DRUG;

ADSORPTION; ARTICLE; CONTAINER; DRUG IDENTIFICATION; DRUG URINE LEVEL; HUMAN; HUMAN EXPERIMENT; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NORMAL HUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; URINALYSIS;

ADSORPTION; CHROMATOGRAPHY, LIQUID; HUMANS; RECEPTORS, LYSOSPHINGOLIPID; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

BOVINAE;

EID: 75349107582     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2009.12.031     Document Type: Article

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