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Volumn 7, Issue 5, 2012, Pages

K65r in subtype C HIV-1 isolates from patients failing on a first-line regimen including d4t or azt: Comparison of sanger and UDP sequencing data

Author keywords

[No Author keywords available]

Indexed keywords

EFAVIRENZ; LAMIVUDINE; NEVIRAPINE; NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR; RECEPTOR SUBTYPE; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; STAVUDINE; ZIDOVUDINE;

EID: 84861205409     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0036549     Document Type: Article
Times cited : (11)

References (18)
  • 1
    • 77950197798 scopus 로고    scopus 로고
    • Analysis of RT sequences of subtype C HIV-type 1 isolates from indian patients at failure of a first-line treatment according to clinical and/or immunological WHO guidelines
    • Deshpande A, Jeannot AC, Schrive MH, Wittkop L, Pinson P, et al. (2010) Analysis of RT sequences of subtype C HIV-type 1 isolates from indian patients at failure of a first-line treatment according to clinical and/or immunological WHO guidelines. AIDS Res Hum Retroviruses 3: 343-350.
    • (2010) AIDS Res Hum Retroviruses , vol.3 , pp. 343-350
    • Deshpande, A.1    Jeannot, A.C.2    Schrive, M.H.3    Wittkop, L.4    Pinson, P.5
  • 2
    • 67651083232 scopus 로고    scopus 로고
    • High frequency of clinically significant mutations after first-line generic highly active antiretroviral therapy failure: implications for second-line options in resource-limited settings
    • Kumarasamy N, Madhavan K, Venkatesh K, Saravanan S, Kantor R, et al. (2009) High frequency of clinically significant mutations after first-line generic highly active antiretroviral therapy failure: implications for second-line options in resource-limited settings. Clin Infect Dis 49: 306-309.
    • (2009) Clin Infect Dis , vol.49 , pp. 306-309
    • Kumarasamy, N.1    Madhavan, K.2    Venkatesh, K.3    Saravanan, S.4    Kantor, R.5
  • 3
    • 70849120990 scopus 로고    scopus 로고
    • The K65R mutation in HIV-1 reverse transcriptase: genetic barriers, resistance profile and clinical implications
    • Brenner BG, Coutsinos D, (2009) The K65R mutation in HIV-1 reverse transcriptase: genetic barriers, resistance profile and clinical implications. HIV Ther 3: 583-594.
    • (2009) HIV Ther , vol.3 , pp. 583-594
    • Brenner, B.G.1    Coutsinos, D.2
  • 4
    • 80051589041 scopus 로고    scopus 로고
    • Antiretroviral resistance patterns and factors associated with resistance in adult patients failing NNRTI-based regimens in the Western Cape, South Africa
    • van Zyl GU, van der Merwe L, Claassen M, Zeier M, Preiser W, (2011) Antiretroviral resistance patterns and factors associated with resistance in adult patients failing NNRTI-based regimens in the Western Cape, South Africa. J Med Virol 83: 1764-1769.
    • (2011) J Med Virol , vol.83 , pp. 1764-1769
    • van Zyl, G.U.1    van der Merwe, L.2    Claassen, M.3    Zeier, M.4    Preiser, W.5
  • 5
    • 70349656911 scopus 로고    scopus 로고
    • Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria
    • Hawkins CA, Chaplin B, Idoko J, Ekong E, Adewole I, et al. (2009) Clinical and genotypic findings in HIV-infected patients with the K65R mutation failing first-line antiretroviral therapy in Nigeria. J Acquir Immune Defic Syndr 52: 228-234.
    • (2009) J Acquir Immune Defic Syndr , vol.52 , pp. 228-234
    • Hawkins, C.A.1    Chaplin, B.2    Idoko, J.3    Ekong, E.4    Adewole, I.5
  • 6
    • 57049168210 scopus 로고    scopus 로고
    • HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy
    • Pillay V, Pillay C, Kantor R, Venter F, Levin L, et al. (2008) HIV type 1 subtype C drug resistance among pediatric and adult South African patients failing antiretroviral therapy. AIDS Res Hum Retroviruses 11: 1449-1454.
    • (2008) AIDS Res Hum Retroviruses , vol.11 , pp. 1449-1454
    • Pillay, V.1    Pillay, C.2    Kantor, R.3    Venter, F.4    Levin, L.5
  • 7
    • 67650395240 scopus 로고    scopus 로고
    • The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy
    • Hosseinipour MC, van Oosterhout JJ, Weigel R, Phiri S, et al. (2009) The public health approach to identify antiretroviral therapy failure: high-level nucleoside reverse transcriptase inhibitor resistance among Malawians failing first-line antiretroviral therapy. J AIDS Jun 1;23 (9): 1127-34.
    • (2009) J AIDS Jun 1 , vol.23 , Issue.9 , pp. 1127-1134
    • Hosseinipour, M.C.1    van Oosterhout, J.J.2    Weigel, R.3    Phiri, S.4
  • 8
    • 33845242455 scopus 로고    scopus 로고
    • High prevalence of the K65R mutation in human immunodeficiency virus type 1 subtype C isolates from infected patients in Botswana treated with didanosine-based regimens
    • Avalos A, Brenner B, Gaolathe T, Mine M, Gaseitsiwe S, et al. (2006) High prevalence of the K65R mutation in human immunodeficiency virus type 1 subtype C isolates from infected patients in Botswana treated with didanosine-based regimens. Antimicrob Agents Chemother 50: 4182-4185.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 4182-4185
    • Avalos, A.1    Brenner, B.2    Gaolathe, T.3    Mine, M.4    Gaseitsiwe, S.5
  • 9
    • 59649120492 scopus 로고    scopus 로고
    • Template usage is responsible for the preferential acquisition of the K65R reverse transcriptase mutation in subtype C variants of human immunodeficiency virus type 1
    • Coutsinos D, Invernizzi CF, Xu H, Moisi D, Oliveira M, et al. (2009) Template usage is responsible for the preferential acquisition of the K65R reverse transcriptase mutation in subtype C variants of human immunodeficiency virus type 1. J Virol 83: 2029-2033.
    • (2009) J Virol , vol.83 , pp. 2029-2033
    • Coutsinos, D.1    Invernizzi, C.F.2    Xu, H.3    Moisi, D.4    Oliveira, M.5
  • 10
    • 77649215613 scopus 로고    scopus 로고
    • Factors affecting template usage in the development of K65R resistance in subtype C variants of HIV type-1
    • Coutsinos D, Invernizzi CF, Xu H, Brenner BG, Wainberg MA, (2010) Factors affecting template usage in the development of K65R resistance in subtype C variants of HIV type-1. Antivir Chem Chemother 20: 117-131.
    • (2010) Antivir Chem Chemother , vol.20 , pp. 117-131
    • Coutsinos, D.1    Invernizzi, C.F.2    Xu, H.3    Brenner, B.G.4    Wainberg, M.A.5
  • 11
    • 79957805294 scopus 로고    scopus 로고
    • A template-dependent dislocation mechanism potentiates K65R reverse transcriptase mutation development in subtype C variants of HIV-1
    • Coutsinos D, Invernizzi CF, Moisi D, Oliveira M, Martinez-Cajas JL, et al. (2011) A template-dependent dislocation mechanism potentiates K65R reverse transcriptase mutation development in subtype C variants of HIV-1. PLoS One 6: e20208.
    • (2011) PLoS One , vol.6
    • Coutsinos, D.1    Invernizzi, C.F.2    Moisi, D.3    Oliveira, M.4    Martinez-Cajas, J.L.5
  • 12
    • 70349428513 scopus 로고    scopus 로고
    • Signature nucleotide polymorphisms at positions 64 and 65 in reverse transcriptase favor the selection of the K65R resistance mutation in HIV-1 subtype C
    • Invernizzi CF, Coutsinos D, Oliveira M, Moisi D, Brenner BG, et al. (2009) Signature nucleotide polymorphisms at positions 64 and 65 in reverse transcriptase favor the selection of the K65R resistance mutation in HIV-1 subtype C. J Infect Dis 200: 1202-1206.
    • (2009) J Infect Dis , vol.200 , pp. 1202-1206
    • Invernizzi, C.F.1    Coutsinos, D.2    Oliveira, M.3    Moisi, D.4    Brenner, B.G.5
  • 13
    • 77956204474 scopus 로고    scopus 로고
    • Nucleic acid template and the risk of a PCR-Induced HIV-1 drug resistance mutation
    • Varghese V, Wang E, Babrzadeh F, Bachmann MH, Shahriar R, et al. (2010) Nucleic acid template and the risk of a PCR-Induced HIV-1 drug resistance mutation. PLoS One 5: e10992.
    • (2010) PLoS One , vol.5
    • Varghese, V.1    Wang, E.2    Babrzadeh, F.3    Bachmann, M.H.4    Shahriar, R.5
  • 14
    • 80052959048 scopus 로고    scopus 로고
    • Prevalence of low-level HIV-1 variants with reverse transcriptase mutation K65R and the effect of antiretroviral drug exposure on variant levels
    • Kozal MJ, Chiarella J, St John EP, Moreno EA, Simen BB, et al. (2011) Prevalence of low-level HIV-1 variants with reverse transcriptase mutation K65R and the effect of antiretroviral drug exposure on variant levels. Antivir Ther 16: 925-929.
    • (2011) Antivir Ther , vol.16 , pp. 925-929
    • Kozal, M.J.1    Chiarella, J.2    St John, E.P.3    Moreno, E.A.4    Simen, B.B.5
  • 15
    • 82455163687 scopus 로고    scopus 로고
    • Drug Resistance Mutations in HIV Type 1 Isolates from Naive Patients Eligible for First Line Antiretroviral Therapy in JJ Hospital, Mumbai, India. AIDS Res Hum Retroviruses
    • Deshpande A, Karki S, Recordon-Pinson P, Fleury HJ, (2011) Drug Resistance Mutations in HIV Type 1 Isolates from Naive Patients Eligible for First Line Antiretroviral Therapy in JJ Hospital, Mumbai, India. AIDS Res Hum Retroviruses. AIDS Res Hum Retroviruses 27: 1345-1347.
    • (2011) AIDS Res Hum Retroviruses , vol.27 , pp. 1345-1347
    • Deshpande, A.1    Karki, S.2    Recordon-Pinson, P.3    Fleury, H.J.4
  • 16
    • 61849160367 scopus 로고    scopus 로고
    • Low-abundance drug-resistant HIV-1 variants: finding significance in an era of abundant diagnostic and therapeutic options
    • Shafer RW, (2009) Low-abundance drug-resistant HIV-1 variants: finding significance in an era of abundant diagnostic and therapeutic options. J Infect Dis 199: 610-612.
    • (2009) J Infect Dis , vol.199 , pp. 610-612
    • Shafer, R.W.1
  • 17
    • 79952327973 scopus 로고    scopus 로고
    • Detection of low-level K65R variants in nucleoside reverse transcriptase inhibitor-naive chronic and acute HIV-1 subtype C infections
    • Li JF, Lipscomb JT, Wei X, Martinson NA, Morris L, et al. (2011) Detection of low-level K65R variants in nucleoside reverse transcriptase inhibitor-naive chronic and acute HIV-1 subtype C infections. J Infect Dis 203: 798-802.
    • (2011) J Infect Dis , vol.203 , pp. 798-802
    • Li, J.F.1    Lipscomb, J.T.2    Wei, X.3    Martinson, N.A.4    Morris, L.5
  • 18
    • 75749120998 scopus 로고    scopus 로고
    • Development of an allele-specific PCR for detection of the K65R resistance mutation in patients infected with subtype C human immunodeficiency virus type 1
    • Toni TA, Brenner BG, Asahchop EL, Ntemgwa M, Moisi D, et al. (2010) Development of an allele-specific PCR for detection of the K65R resistance mutation in patients infected with subtype C human immunodeficiency virus type 1. Antimicrob Agents Chemother 54: 907-911.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 907-911
    • Toni, T.A.1    Brenner, B.G.2    Asahchop, E.L.3    Ntemgwa, M.4    Moisi, D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.