Influenza HA DNA induces Th1 cells and protection despite limited antibody responses

International Congress Series

Volumn 1219, Issue C, 2001, Pages 911-915

  Johnson, Patricia A ^a   Conway, Margaret ^a   Daly, Janet ^b   Nicolson, Carolyn ^b   Robertson, James S ^b   Mills, Kingston H G ^a  

^a NATIONAL UNIVERSITY OF IRELAND   (Ireland)

^b NATIONAL INSTITUTE FOR BIOLOGICAL STANDARDS AND CONTROL   (United Kingdom)

Author keywords

DNA vaccine; Haemagglutinin; Influenza virus; Th1 cells

Indexed keywords

EID: 84861190411     PISSN: 05315131     EISSN: None     Source Type: Book Series    
DOI: 10.1016/S0531-5131(01)00367-3     Document Type: Article

References (5)

1. Liu, M.A., Overview of DNA vaccines. Ann. N. Y. Acad. Sci. 772 (1995), 15–20.
2. Bot, A., Immunoglobulin deficient mice generated by gene targeting as models for studying the immune response. Int. Rev. Immunol. 13 (1996), 327–340.
3. Topham, D.J., Tripp, R.A., Hamilton-Easton, A.M., Sara, S.R., Doherty, P.C., Quantitative analysis of the influenza virus-specific CD4+ T cell memory in the absence of B cells and Ig. J. Immunol. 157 (1996), 2947–2952.
4. Donnelly, J.J., DNA vaccines. Annu. Rev. Immunol. 15 (1997), 617–648.
5. Johnson, P.A., Conway, M.A., Daly, J., Nicolson, C., Robertson, J., Mills, K.H.G., Plasmid DNA encoding influenza virus haemagglutinin induces Th1 cells and protection against respiratory infection despite its limited ability to generate antibody responses. J. Gen. Virol. 81 (2000), 1737–1745.